Biphasic cardiac pacer

• US 4,543,956 A
• Filed: 05/24/1984
• Issued: 10/01/1985
• Est. Priority Date: 05/24/1984
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Inventors: Herscovici, Harry
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US06/613,888
• Time in Patent Office: 495 Days
• Field of Search: 128/419 PG
• US Class Current: 607/13
• CPC Class Codes: A61N 1/371 Capture, i.e. successful stimulation

Abstract

A biphasic cardiac pacer is provided having a novel system for detecting the evoked response from the heart after a stimulating pulse is applied. A relatively short, high absolute amplitude stimulating pulse is applied to the heart. Thereafter, a compensating pulse having an absolute amplitude that is smaller than the absolute amplitude of the stimulating pulse, and having a duration that is longer than the duration of the stimulating pulse, is provided. The stimulating pulse and compensating pulse together comprise a biphasic waveform that provides rapid electrode charge neutralization and enhances subsequent capture detection. The biphasic waveform is automatically and dynamically balanced so that the electrical charge of the stimulating pulse portion is equal to the electrical charge of the compensating pulse portion. After the compensating pulse is provided, the evoked response is detected using the same electrodes that are used for providing the stimulating and compensating pulses.

Claims

1. A method of detecting evoked response from the heart, comprising the steps of:

providing a rectangular stimulating pulse;

determining the charge of the stimulation pulse;

thereafter generating a rectangular compensating pulse having an opposite polarity to the stimulating pulse and having an absolute amplitude that is less than the absolute amplitude of the stimulating pulse and having a duration that is continued during the generation of the compensating pulse until the charge of the compensating pulse is equal to the charge of the stimulating pulse; and

thereafter detecting the evoked response using the same electrodes that are used for providing the stimulating and compensating pulses.

2. A method as described in claim 1, wherein the charge of the stimulating pulse is determined by integrating the stimulating pulse and the charge of the compensating pulse is determined by integrating the compensating pulse and generating the compensating pulse until the integral of the compensating pulse equals the integral of the stimulating pulse.

3. A method as described in claim 1, in which the stimulating pulse is a negative pulse and has a duration that is substantially less than the duration of the compensating pulse.

4. A method as described in claim 1, in which the charge of the compensation pulse is equalized to the charge of the stimulation pulse by providing a stimulation pulse of preset duration, sampling the stimulation pulse, storing the stimulation pulse amplitude at each sample, constructing the compensating pulse by issuing n samples for each stimulation pulse sample at 1/n times its amplitude.

5. A method as described in claim 1, in which capture is detected by blanking the output of a capture detector for a predetermined time after the stimulating pulse is issued, and thereafter providing a time window for seeking an evoked response.

6. A method as described in claim 1, in which the stimulation pulse is provided by multiplying the pacer'"'"'s battery voltage using a voltage multiplier.

7. A method as described in claim 1, in which equal charges for any ratio between the amplitudes of the stimulating pulse and the compensating pulse are automatically provided.

8. A cardiac pacer in which stimulating pulses may be provided to a chamber of the heart via a stimulating electrode connected to the heart, which comprises:

means for providing a rectangular stimulating pulse to said electrode;

means for determining the charge of the stimulation pulse;

means for thereafter generating a rectangular compensating pulse to said electrode, said compensating pulse having an opposite polarity to the stimulating pulse and having an absolute amplitude that is less than the absolute amplitude of the stimulating pulse and having a duration that is continued during the generation of the compensating pulse until the charge of the compensating pulse is equal to the charge of the stimulating pulse; and

means for thereafter detecting the evoked response using the same electrodes that are used for providing the stimulating and compensating pulses.

9. A cardiac pacer as described in claim 8, in which the stimulating pulse is a negative pulse, and has a duration that is substantially less than the duration of the compensating pulse.

10. A cardiac pacer as described in claim 8, including means for integrating successively the stimulation pulse and the compensating pulse for equalizing the charge of the compensating pulse to the charge of the stimulation pulse.

11. A cardiac pacer as described in claim 8, including a capture detector, said capture detector having means for providing a time window for seeking an evoked response, said time window being set to commence subsequent to the trailing edge of the compensating pulse.

12. A cardiac detector as described in claim 8, in which the pacer includes a battery power source, and including a voltage multiplier for increasing the voltage applied to the stimulation pulse providing means.

13. A cardiac pacer as described in claim 8, including means for dynamically providing equal charges for any ratio between the amplitudes of the stimulating pulse and the compensating pulse.