Microtitration plate

• US 4,545,958 A
• Filed: 04/18/1983
• Issued: 10/08/1985
• Est. Priority Date: 04/19/1982
• Status: Expired due to Fees

• Current Assignee: Dade Behring Marburg GmbH (Siemens AG)
• Original Assignee: Behringwerke Aktiengesellschaft (Sanofi )
• Inventors: Dopatka, Hans-Detlef
• Primary Examiner(s): Richman, Barry S.
• Assistant Examiner(s): Gzybowski, Michael S.
• Application Number:
  US06/485,831
• Time in Patent Office: 904 Days
• Field of Search: 206/563, 211/74, 356/244, 220/21, 220/23.8, 422/99, 422/102, 422/104, 435/293, 435/300, 435/301, 436/809
• US Class Current: 422/553
• CPC Class Codes: B01L 3/50851 specially adapted for heating or cooling samples laboratory heating apparatus B01L7/00; incubators C12M
• CPC Class Codes: Y10S 436/809 Multifield plates or multicontainer arrays

Abstract

A microtitration plate wherein a frame and a central part are separated from one another via a continuous break and ridges are arranged at the lower face of the plate so that differences in temperature on heating between edge vessels and vessels in the central part are avoided, said differences in temperature causing the well-known "edge-effect".

Claims

1. A microtitration plate adapted to be heated, comprising:

a continuous frame part having sidewalls and an upper surface extending within said frame part and projecting inwardly a predetermined distance from said sidewalls, said upper surface having an inwardly directed facing edge;

a central well portion situated within said frame part interiorly of said facing edge and having a plurality of vessels mounted thereon, said vessels having a predetermined height and width, said facing edge and the outer surface of said well portion defining a gap between said frame part and said well portion; and

an arrangement of ridges, said ridges being transverse support members integrally connected to diametrically opposed points on said sidewalls, said ridges also being spaced longitudinally within said frame part, said ridges supporting said central well portion within said frame part.

2. A microtitration plate as recited in claim 1, wherein said plurality of vessels are arranged in rows and each one of said rows is disposed adjacent one of said ridges.

3. A microtitration plate as recited in claim 1, wherein said ridges have ends that are tapered at the regions of connection between said ridges and said sidewall.

4. A microtitration plate as recited in claim 1, wherein the height of said vessels is greater than the width of said vessels.

5. A microtitration plate as recited in claim 1, including means for heating said microtitration plate.

6. A microtitration plate as recited in claim 1, wherein said sidewalls include a base portion having a plurality of spaced indentations.

7. A microtitration plate as recited in claim 6, wherein said indentations are individually positioned between adjacent ones of said longitudinally spaced ridges to facilitate fluid movement through the sidewalls.