Parenteral agent dispensing equipment

• US 4,548,598 A
• Filed: 02/03/1984
• Issued: 10/22/1985
• Est. Priority Date: 10/09/1981
• Status: Expired due to Term

• Current Assignee: ALZA Corporation (Johnson & Johnson)
• Original Assignee: ALZA Corporation (Johnson & Johnson)
• Inventors: Theeuwes, Felix
• Primary Examiner(s): Truluck, Dalton L.
• Application Number:
  US06/577,241
• Time in Patent Office: 627 Days
• Field of Search: 604/56, 604/80-86, 604/251, 604/890, 604/892
• US Class Current: 604/85
• CPC Class Codes: A61M 5/1407 Infusion of two or more substances

Abstract

A parenteral delivery system and a formulation chamber are disclosed for administering a beneficial agent. The parenteral delivery system comprises a drip chamber and a formulation chamber. The formulation chamber comprises a wall surrounding an internal space and it has an inlet for admitting a liquid into the formulation chamber and an outlet for letting an agent formulation leave the formulation chamber The chamber houses an agent delivery system for releasing a beneficial agent into a liquid that enters the chamber.

Claims

1. A formulation chamber for use in a parenteral delivery system, comprising:

(a) a wall surrounding a lumen;

(b) an inlet for admitting a fluid into the chamber;

(c) an outlet for letting fluid leave the chamber; and

(d) a plurality of tiny pills in the chamber, the tiny pills comprising;

(1) a solid core of a beneficial parenterally administrable agent; and

,

(2) a wall surrounding the parenterally administrable agent, the wall formed of a parenterally acceptable material that releases the parenterally acceptable agent from the tiny pills into a parenterally acceptable fluid that enters the formulation chamber and contacts the tiny pills.

2. The formulation chamber for use in a parenteral delivery system according to claim 1, wherein the chamber comprises a film that aids in controlling the rate of release of agent formulation from the formulation chamber.

3. The formulation chamber for use in a parenteral delivery system according to claim 1, wherein the chamber comprises a porous film that aids in controlling the rate of release of agent formulation from the formulation chamber.

4. The formulation chamber for use in a parenteral delivery system according to claim 1, wherein the chamber comprises a perforated grid that supports the tiny pills in the chamber.

5. The formulation chamber for use in a parenteral delivery system according to claim 1, wherein the parenteral delivery system comprises a drip chamber in fluid communication with the formulation chamber.

6. An intravenous delivery system for administering a beneficial agent intravenously to a human, comprising:

(a) a container of a pharmaceutically acceptable intravenous fluid;

(b) a drip chamber in fluid communication with the container for determining the rate of fluid flow through the intravenous delivery system; and

,

(c) a formulation chamber comprising;

(1) a wall surrounding a lumen;

(2) a plurality of tiny pills containing agent in the lumen; and

,

(3) wherein the formulation chamber is in fluid communication with the drip chamber such that fluid flows into the formulation chamber and forms with agent released by the pills an agent formulation over time.