Detection and imaging of objects in scattering media by light irradiation

• US 4,555,179 A
• Filed: 11/08/1982
• Issued: 11/26/1985
• Est. Priority Date: 11/08/1982
• Status: Expired due to Term

• Current Assignee: Firma G. Rodenstock Instrumente GmbH
• Original Assignee: John Langerholc, Thorsteinn Halldorsson
• Inventors: Halldorsson, Thorsteinn, Langerholc, John
• Primary Examiner(s): Willis, Davis L.
• Assistant Examiner(s): Koren, Matthew W.
• Application Number:
  US06/439,867
• Time in Patent Office: 1,114 Days
• Field of Search: 356/52, 356/53, 356/66, 356/342, 356/237, 356/239, 356/446, 250/563, 250/572, 128/633, 128/665
• US Class Current: 356/342
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: G01N 2021/178 Methods for obtaining spatial resolution of the property being measured
• CPC Class Codes: G01N 2021/4709 Backscatter
• CPC Class Codes: G01N 21/314 with comparison of measurements at specific and non-specific wavelengths dual wavelength spectrometry G01J3/427
• CPC Class Codes: G01N 21/4795 spatially resolved investigating of object in scattering medium in vivo A61B
• CPC Class Codes: G01S 17/89 for mapping or imaging

Abstract

A method and system are described for the detection and imaging of objects and structures in scattering media using light radiation. The medium is scanned with a strongly collimated light beam (2). The light power (P_b) scattered backward from the medium is detected by a receiver (17) and plotted along the scanning path. Objects (4) buried in the medium (9) are detected by the differential variation of the received light power. Information as to the size, location and depth of the objects can be obtained. The illumination by strongly collimated laser light at one or several wavelengths is preferred.

Claims

1. A method for detecting and imaging objects surrounded by a scattering medium comprising:

illuminating the scattering medium with a collimated light beam incident upon and penetrating said medium;

scanning the collimated light beam through a region of the scattering medium and at successive positions along a scanning path across a selected scanning area;

detecting the back scattered light in the scattering zone around the locus of incidence of the collimated light beam on the scattering medium and measuring the intensity of the back scattered light from the scattering zone at successive positions along the scanning path across said scanning area;

registering the measured intensity of light from the scattering zone at said successive positions along the scanning path; and

associating differential measurements registered along the scanning path with the possible presence of an object.

2. The method of claim 1, further comprising the step of blocking or obscuring the back scattered light from the center of the scattering zone, thereby detecting and measuring only the back scattered light from the periphery of the scattering zone and thereby increasing the sensitivity to intensify differences between successive positions of the scanning path.

3. The method of claim 1, wherein the step of illuminating the scattering medium with a collimated light beam comprises illuminating the medium by light of at least two constituent wavelengths, and further comprising the steps of:

separating the backscattered light from said scattering zone into at least two light paths of said at least two constituent wavelengths;

detecting and measuring the intensity of the light at said at least two constituent wavelengths;

measuring the difference in intensity between said at least two constituent wavelengths at successive positions across the scanning paths;

registering said difference measurements for successive positions along the scanning path; and

associating differences in said difference measurements with the presence of possible objects in the scattering medium.

4. An apparatus for detecting and imaging objects in a scattering medium by light irradiation, comprising:

light source means delivering a collimated light beam incident upon and penetrating said scattering medium in a scattering zone;

optical scanning means operatively arranged relative to said light source means and said scattering medium for deflecting the light beam through a region of the scattering medium at successive positions along a scanning path across a specified scanning area;

photodetector means operatively arranged for receiving and detecting substantially the full angular distribution of backscattered light returning from said scattering zone around the locus of incidence of the light beam, said photodetector means further comprising means for measuring the intensity of said backscatter light received from the scattering zone; and

register means for registering the values of said intensity measurements at said successive positions along the scanning path, said apparatus further comprising first polarization filter means placed in the path of said collimated light beam incident on the scattering medium for linear polarization of said incident light beam, and second polarization filter means having a polarization direction perpendicular to the first polarization filter means, said second polarization filter means being interposed in the path of the backscattered light received from the scattering zone.

5. The apparatus of claim 4, wherein said optical scanning means comprises scanning mirror means constructed and arranged for deflection of the collimated light beam along the scanning path across said selected scanning area, said scanning mirror means being arranged for deflection of the backscattered light from said scattering zone to said photodetector means.

6. The apparatus of claim 4, wherein said photodetector means further comprise aperture means comprising a central insert, said aperture means being positioned in the light path of backscattered light from said scattering zone to obscure the central portion of said scattering zone and block the backscattered light from the center of said scattering zone.

7. The apparatus of claim 4, wherein said light source means is selected to deliver a collimated light beam characterized by light of a selected wavelength, and further comprising interference filter means interposed in the path of the backscattered light from said scattering zone, said interference filter means having a characteristic wavelength corresponding substantially to the wavelength of light of the incident collimated light beam thereby to suppress background radiation.

8. The apparatus of claim 4, further comprising light chopper means interposed in the path of the incident collimated light beam delivered by said light source means for modulating the incident light beam at a characteristic frequency, and frequency filter means tuned to said modulating frequency for selectively passing signals corresponding to light which has passed through said light chopper means, said frequency filter means being coupled to the output of said detector means.

9. The apparatus of claim 4, wherein said light source means comprises first and second light sources for delivering a collimated light beam composed of light of at least two different constituent wavelengths;

optical separator means interposed in the path of backscattered light from the scattering zone for separating the backscattered light beam into said at least two constituent wavelengths;

wherein said detector means comprises first and second detectors operatively arranged for respectively receiving the separated light of said at least two constituent wavelengths;

wherein said means for measuring the intensity of backscattered light comprises first and second measuring means for measuring the intensity of light at said at least two constituent wavelengths; and

further comprising means for measuring the difference between the intensity measurements of the light of said at least two constituent wavelengths at successive positions along the scanning path; and

wherein said register means is operatively arranged for registering said difference measurements at successive positions along the scanning path.

10. The apparatus of claim 9, wherein said first and second light source means are selected and operatively arranged to deliver the light of said at least two constituent wavelengths, at wavelengths selected with reference to the scattering medium containing the objects to be detected and imaged so that the scattering medium has approximately the same absorption properties at both said at least two constituent wavelengths.

11. The apparatus of claim 9, wherein said first and second light sources comprise lasers.

12. The apparatus of claim 9, wherein said optical separator means comprises a dichroitic mirror.

13. The apparatus of claim 4, wherein said register means comprises a raster image display means for plotting and displaying the intensity measurements for visual indication of the possible presence of objects in the scattering medium.

14. The apparatus of claim 4, wherein said light source means comprises at least one laser.

15. The apparatus of claim 4, wherein said detector means comprises a quandrant detector means for angular discrimination in the detection of backscattered light from the scattering zone.