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Device for in vivo purification of blood

  • US 4,563,170 A
  • Filed: 07/29/1983
  • Issued: 01/07/1986
  • Est. Priority Date: 07/30/1982
  • Status: Expired due to Term
First Claim
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1. An in-vivo blood purification system for use in intra-arterial chemotherapy, said system comprising:

  • a substantially cylindrical double-lumen catheter insertable into the vena cava up to the vicinity of the heart and being formed to provide therein a first channel (B) and, generally parallel thereto, a second channel (A), each said channel being at least partially bounded by the wall of said catheter, and the catheter having a closed tip and a plurality of openings (11) which are laterally positioned in the vicinity of the catheter tip and communicate with said first channel (B), and said second channel (A) terminating with at least two openings (12) in said wall of the catheter, the distance between the lateral opening (11) farthest from the catheter tip and the closest opening (12) of the second channel (A) being not less than 40 mm and not more than 50 mm, and the opening (12) at the end of the second channel (A) having the same size as the inner cross-sectional area of said channel (A);

    means (8, etc.) connected to said second channel (A) for pumping large amounts of blood out of the vena cava through said channel;

    means (1, etc.) for sujecting said blood to ultrafiltration; and

    means (9, etc.) connected to said first channel (B) for returning, simultaneously with the withdrawal of blood from said second channel (A), the filtrate to the vena cava through said first channel (B) together with a requisite amount of substitute fluid.

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