Selectively permeable film and ion sensor

• US 4,563,263 A
• Filed: 01/15/1982
• Issued: 01/07/1986
• Est. Priority Date: 01/15/1982
• Status: Expired due to Term

• Current Assignee: Terumo Corporation
• Original Assignee: Terumo Corporation
• Inventors: Oyama, Noboru, Matsuda, Hiroaki, Tsuchida, Eishun, Shimomura, Takeshi, Ushizawa, Norihiko, Ohnuki, Yukio
• Primary Examiner(s): Niebling, John F.
• Assistant Examiner(s): Boggs, Jr., B. J.
• Application Number:
  US06/339,715
• Time in Patent Office: 1,453 Days
• Field of Search: 204/195 M, 204/1 H, 204/290 R, 204/56 R, 204/416, 204/433, 204/434, 204/418, 204/415, 428/458, 428/457
• US Class Current: 204/418
• CPC Class Codes: G01N 27/3335 the membrane containing at least one organic component G01N27/3271 takes precedence; aspects concerning the enzyme reagent in enzyme electrodes C12Q1/001

Abstract

A selectively permeable film directly applied to coat the surface of an electroconductive element, said electively permeable film comprising a polymer which is derived from at least one aromatic compound selected from the group of nitrogen-containing aromatic compounds or from the group of hydroxy aromatic compounds. The nitrogen-containing aromatic compounds are aniline, 2-aminobenzotrifluoride, 2-aminopyridine, 2,3-diaminopyridine, 4,4'"'"'-diaminodiphenyl ether, 4,4'"'"'-methylenedianiline, tyramine, N-(o-hydroxybenzyl)-aniline and pyrrole. The film coated on the electrode surfaces permits selective passage of ions and the electrode can be used as an ions sensor for measuring the concentration of ions in solutions.

Claims

1. A system for measuring the concentration of hydrogen ions in a test solution by electrode potential response or current response, comprising:

a hydrogen ion sensor adapted to contact said test solution; and

means coupled to said hydrogen ion sensor for measuring the electrical potential difference between said hydrogen ion sensor while contacting said test solution and a reference potential;

said hydrogen ion sensor consisting essentially of an electroconductive element having applied to a surface thereof a polymer film derived from at least one aromatic compound selected from the group consisting of nitrogen-containing aromatic compounds selected from the group consisting of aniline, 2-aminobenzotrifluoride, 2-aminopyridine, 2,3-diaminopyridine, 4,4'"'"'-diaminodiphenyl ether, 4,4'"'"'-methylenedianiline, tyramine, N-(o-hydroxybenzyl)aniline, and pyrrole and a hydroxy aromatic compound selected from compounds having the formula ##STR3## wherein Ar is an aromatic ring, R is selected from the group consisting of alkyl, aryl, alkylcarbonyl, arylcarbonyl hydroxyalkyl, carboxyl, aldehyde, and hydroxyl, and l is zero or the valency number of the Ar group.

2. The system of claim 1, wherein the polymer film is a film polymerized by electrochemical oxidation on the surface of the electroconductive element.

3. The system of claim 1, wherein the polymer film is a film obtained by applying to the surface of the electroconductive element a solution of the synthesized polymer.

4. The system of claim 1, wherein the polymer film is derived from said nitrogen-containing aromatic compound.

5. The system of claim 1, wherein said hydrogen ion sensor is a pH sensor.

6. The system of claim 1, wherein the polymer film is derived from said hydroxy aromatic compound.

7. The system of claim 1, wherein the hydroxy aromatic compound is at least one member selected from the group consisting of phenol, dimethyl phenol, hydroxypyridine, o- and m-benzyl alcohols, o-, m- and p-hydroxybenzaldehydes, o-, m- and p-hydroxyacetophenones, o-, m- and p-hydroxypropiophenones, o-, m- and p-benzophenols, o-, m- and p-hydroxybenzophenones, o-, m- and p-carboxyphenols, diphenyl phenol, 2-methyl-8-hydroquinoline, 5-hydroxy-1,4-naphthoquinone, 4-(p-hydroxyphenyl)-2-butanone, 1,5-dihydroxy-1,2,3,4-tetrahydronaphthalene and bis-phenol A.

8. A system for measuring the concentration of hydrogen ions in a test solution by electrode potential response or current response, comprising:

a hydrogen ion sensor adapted to contact said test solution; and

means coupled to said hydrogen ion sensor for measuring the electrical potential difference between said hydrogen ion sensor while contacting said test solution and a reference potential;

said hydrogen ion sensor comprising an electroconductive element having applied to a surface thereof a polymer film derived from at least one aromatic compound selected from the group consisting of nitrogen-containing aromatic compounds selected from the group consisting of aniline, 2-aminobenzotrifluoride, 2-aminopyridine, 2,3-diaminopyridine, 4,4'"'"'-diaminodiphenyl ether, 4,4'"'"'-methylenedianiline tyramine, N-(o-hydroxybenzyl)aniline, and pyrrole.