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Composite polymeric material for biological and medical application and the method for its preparation

  • US 4,563,490 A
  • Filed: 11/18/1983
  • Issued: 01/07/1986
  • Est. Priority Date: 07/21/1980
  • Status: Expired due to Fees
First Claim
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1. Composite polymeric material for biological and medical application comprising a matrix of at least the following components:

  • 1-99 weight percent of a substantially water insoluble hydrophilic polymer or copolymer based on methacrylate or acrylate, 1-99 weight percent of a fibrillar collagen, 0-2.5 weight percent of a crosslinking agent, related to both polymeric components, said material being prepared by dispersing the fibrillar collagen in a solution or in a high swollen dispersion of the synthetic hydrophilic polymer or copolymer in a lyotropic agent which maintains the mutual miscibility of said components and by the subsequent removal of the lyotropic agent forming a matrix of said synthetic polymer or copolymer interpregnated with collagen or a matrix of collagen interpregnated with said synthetic polymer or copolymer.

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