Fluid transfer system

• US 4,564,054 A
• Filed: 05/02/1984
• Issued: 01/14/1986
• Est. Priority Date: 05/20/1983
• Status: Expired due to Fees

• Current Assignee: Carmel Pharma AB (Becton, Dickinson & Co)
• Original Assignee: Bengt Gustavsson
• Inventors: Gustavsson, Bengt
• Primary Examiner(s): Bell, Jr., Houston S.
• Application Number:
  US06/606,184
• Time in Patent Office: 622 Days
• Field of Search: 141/19, 141/329, 141/330, 141/286, 141/382-386, 604/411, 604/414, 604/198, 604/192, 604/201, 604/253
• US Class Current: 141/329
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2072 for internal venting
• CPC Class Codes: A61J 1/2075 for external venting
• CPC Class Codes: A61J 1/2082 for gas filtration
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 5/3243 being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel devices for protecting guide needles in combination with catheters A61M25/0612

Abstract

A device is disclosed for preventing air contamination when transferring a substance from one vessel to a second vessel. The device is attached or connectible to the vessel and comprises a first member, in which a puncturing member e.g. a needle, provided with a passage is enclosed. The first member has a sealing member, e.g. a membrane, through which the needle can be passed. The device further comprises a second chamber, which is detachably connectable to the first member and which also has a sealing member, e.g. a membrane. When the first and second members are connected to each other the two sealing members are located in a position with respect to each other so that they can be penetrated by the puncturing member which is movable with respect to the sealing members.

Claims

1. A fluid transfer system for transferring a substance from a first vessel to a second vessel avoiding contamination, said system being attached or connectible to said first vessel or a cover enclosing the first vessel, comprising:

(1) a first member hermetically enclosing a puncturing member provided with a passageway, said first member having a first sealing member for being passed and retracted therethrough, at which the sealing effect of said sealing member is maintained after retraction of the puncturing member;

(2) a second member having a second sealing member;

mating connection means arranged on said first and second members for providing a releasable locking of said members with respect to each other, said sealing members in the connected position of the first and second members being located in a position with respect to each other so that they can be penetrated by the puncturing member, wherein after transfer of said substance the puncturing member is retractable to a position in which said puncturing member is hermetically enclosed in said first member and the first and second members are disconnectable from each other.

2. The device according to claim 1 wherein said sealing members in the connected position of the first and second members are brought to tight apposition against each other.

3. The device according to claim 2 wherein said first vessel has a closure means and said second member forms a unit with said closure means of the first vessel.

4. The device according to claim 3 wherein said first member is so designed that the distance between the first sealing member and the attachment for the puncturing member can be lengthened and shortened.

5. The device according to claim 4, wherein the first member has flexible side walls whereby through pressing the walls together in the axial direction of the puncturing member, said puncturing member passes through the sealing members.

6. The device according to claim 5, wherein the puncturing member is displaceably arranged in the first member and guided along the inside thereof.

7. The device according to claim 6, wherein the first member further comprises a cylinder and the puncturing member provided with a ventilated piston guide slidingly received within said cylinder, the puncturing member being attached to a connection piece arranged to firmly receive said second vessel and a seal is formed between the puncturing member and the interior of said cylinder.

8. The device according to claim 5, wherein the first member further comprises a pair of outer and inner telescoping parts the puncturing member being attached to one telescoping part and the first sealing member being attached to the other telescoping part.

9. The device according to claim 8, wherein the outer telescoping part comprises means for firmly receiving said second vessel, the puncturing member being attached to said outer part and said first sealing member being attached to the inner part, a seal being provided between the interior of the inner part and the outer part and air being admitted to pass between the inside of the outer part and the outside of the inner part, said inner and outer parts being undetachably and unrotatably connected to each other at least in the most extended position.

10. The device according to claim 5, wherein the first member further comprises a pair of parts threaded into each other, the puncturing member being attached to one part and the first sealing member being attached to the other part.

11. The device according to claim 5, wherein the puncturing member is displaceably arranged in the first member by a lever manouverable from the outside thereof.

12. The device according to claim 11, wherein said first sealing member is in the form of a sleeve through which the puncturing member is passed and which in one position is arranged to cover a radial opening in a needle communicating with the transmission channel thereof, the tip of the needle being closed and the needle being movable with respect to said sealing member to a position where the radial opening is exposed.

13. The device according to claim 12, wherein the puncturing member is provided with a radial opening so that the interior of the first vessel can communicate with the interior of the first member in a certain position of the puncturing member and that a sealing is provided for closing said radial opening in a second certain position of the puncturing member.

14. The device according to claim 13, wherein the passage of the puncturing member is arranged to communicate with the interior volume of said first member which makes said second vessel.

15. The fluid transfer system according to claim 1, wherein one end of the second member is attached or connectible to a cannula, a vein catheter, or an infusion device and the opposite end of said second member is connectible to the first member.

16. The device according to claim 15, wherein the device is provided with coupling means arranged to be connected to said first vessel about the bottle-neck thereof.

17. The device according to claim 16, wherein the device is provided with coupling means arranged to be connected to said first vessel in a cavity in a closure means thereof.

18. The device according to claim 17, wherein an expandable bladder is arranged to communicate with the interior of the first vessel for pressure equalization when transferring a substance.

19. The device according to claim 18, wherein said device is provided with a pointed member having a passage therethrough and which can be passed through the closure means of the first vessel, at which the puncturing member is arranged to be passed through said pointed member into the first vessel.

20. The device according to claim 19, wherein said pointed member has a passage communicating with the atmosphere via a liquid-rejecting filter or with an expandable bladder for ventilating the first vessel.

21. The device according to claim 20, wherein said pointed member makes the coupling means for connecting the device to said first vessel.

22. The device according to claim 21, wherein two substantially parallel puncturing members are arranged to pass through the first and second sealing members, one of said puncturing members being arranged to transfer the substance to said second vessel and the second being provided with a passage for ventilating the interior of the first vessel when said second puncturing member is passed through the second sealing member.

23. The device according to claim 22, wherein said passage of said second puncturing member is arranged to ventilate the interior of the first member.

24. The device according to claim 23, wherein the puncturing member over a portion near its free end is surrounded by a further puncturing member attached to the first puncturing member, at which there is a free space between the two puncturing members arranged to ventilate the interior of the first vessel.

25. The device according to claim 10, wherein the puncturing member has a helical end portion a second helical puncturing member being wound about said end portion, said second helical puncturing member having a passage therethrough arranged to ventilate the interior of the first vessel.

26. The device according to claim 25, wherein the pitch of said helical portion and helical puncturing member corresponds to the pitch of thread of the threaded portions of the first member.

27. The device according to claim 26, wherein the first sealing member has a convex sealing surface.