Apparatus and method for stimulating micturition and certain muscles in paraplegic mammals

• US 4,569,351 A
• Filed: 12/20/1984
• Issued: 02/11/1986
• Est. Priority Date: 12/20/1984
• Status: Expired due to Fees

• Current Assignee: Herman M. Finch University of Health Sciences
• Original Assignee: University Of Health Sciences The Chicago Medical School
• Inventors: Tang, Pei C.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Shein, Mitchell J.
• Application Number:
  US06/684,351
• Time in Patent Office: 418 Days
• Field of Search: 128/419 E, 128/419 R, 128/421, 128/642, 128/783-785
• US Class Current: 607/27
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control

Abstract

There is disclosed a new, useful and simple apparatus, and surgical method, for implantation of same, for selective control of evacuating the urinary bladder in mammals by electrical stimulation of the motor innervations of the bladder'"'"'s detrusor urinae muscle. Contractions of this muscle occur by timed electrical pulses conducted by electrodes placed in the fluid of the sacral canal, to conduct electrical stimulus through the fluid in the sacral region of the spinal cord. Nerve roots located in this region of the sacral canal, and which innervate the bladder, are stimulated by the electricity conducted by the fluid, causing contraction of the bladder'"'"'s detrusor muscle, and results in micturition. In preferred form, the apparatus may be used on paraplegic or quadriplegic humans and could be selectively controllable by a paraplegic human. The apparatus may also be used to evacuate the bladder in paraplegic mammals such as dogs and cats. The apparatus can be used to stimulate nerves innervating muscles other than the detrusor in the body, and thereby to exercise the muscles that are paralyzed by a spinal cord injury.

Claims

1. In a method of stimulating the detrusor muscle of the bladder of a mammal that has innervating nerve fibers operatively associated therewith, so as to effect at least partial micturition by the mammal;

the improvement comprising the steps of;

obtaining access to the portion of the sacral canal that is bounded by the bone of the spinal column and is not occupied by the spinal cord, said access being obtained without piercing the dura mater;

emplacing at least two electrodes through the bone of the sacrum into the sacral canal with the free ends of the electrodes immersed in the fluid in the canal but spaced form the dura mater, the spinal cord and the adjacent nerve roots;

and applying timed electrical pulsed, alternating, voltage across the electrodes immersed in the spinal fluid, to effect electrical stimulation of the adjacent nerve roots of the nerve fibers that innervate the detrusor muscle.

2. A method as in claim 1 wherein the step of emplacing electrodes includes dividing one of the two electrodes into at least two equipotential electrodes, thereby providing a total of three electrodes immersed in the spinal fluid.

3. The method of claim 1 wherein said electrical pulse is applied for a duration of at least 0.1 but less than 0.5 seconds.

4. The method of claim 1 wherein said electrical pulse is a frequency of at least 20 Hz Alternating Current but not more than 60 Hz Alternating Current.

5. The method of claim 1 wherein said electrical pulse has an intensity of at least four (4) Volts but less than 8 Volts.

6. In an apparatus for stimulating nerves in the spinal column of an animal for inducing muscle contractions of the detrusor muscle which has innervating nerve fibers operatively associated therewith, the improvement comprising, in combination:

a mounting plate for attachment to the sacral bone;

a plurality of electrical contacts split into at least two equipotential contacts, supported by said mounting plate and projecting through bores in said sacral bone into the body fluid in the sacral canal and spaced from the nerves within the spinal column associated with the sacral bone; and

means holding the mounting plate in tight association with the sacral bone to prevent liquid loss from the sacral canal.

7. The apparatus of claim 6 having at least two but less than 6 electrodes.

8. The apparatus of claim 7 wherein said electrodes are of platinum.

9. The apparatus of claim 8 operatively associated with a source for supplying an electrical signal.