Three phase irradiation treatment process
First Claim
Patent Images
1. In a system for altering cells including treating the cells with a photoactivatable reagent and irradiating said cells and reagent whereby said reagent is caused to be activated and to affect said cells, a three phase method for so treating the blood of a patient comprising the steps of:
- in a first phase,collecting with a collection tubing set, whole blood from a patient having previously been given a pharmaceutically effective amount of a photoactivatable agent;
passing said whole blood into a continuous centrifuge for obtaining plasma and a leukocyte enriched portion;
storing a predetermined volume of said plasma and said leukocyte enriched portion;
returning nonleukocyte enriched portions and any excess plasma to said patient through said collection tubing set;
disconnecting said patient from said collection tubing set;
in a second phase,passing said stored leukocyte enriched portion through an irradiation tubing set, including an irradiation chamber for photoactivating said reagent, until a predetermined level of photoactivation has been achieved; and
in a third phase,returning said irradiated leukocyte enriched portion to said patient through a return tubing set.
2 Assignments
0 Petitions
Accused Products
Abstract
In a system for altering cells such as by irradiating said cells when in contact with a photoactivatable reagent useful for the extracorporeal treatment of a patient'"'"'s blood, a three phase method for performing the operations in a safe and efficacious manner.
-
Citations
6 Claims
-
1. In a system for altering cells including treating the cells with a photoactivatable reagent and irradiating said cells and reagent whereby said reagent is caused to be activated and to affect said cells, a three phase method for so treating the blood of a patient comprising the steps of:
-
in a first phase, collecting with a collection tubing set, whole blood from a patient having previously been given a pharmaceutically effective amount of a photoactivatable agent; passing said whole blood into a continuous centrifuge for obtaining plasma and a leukocyte enriched portion; storing a predetermined volume of said plasma and said leukocyte enriched portion; returning nonleukocyte enriched portions and any excess plasma to said patient through said collection tubing set; disconnecting said patient from said collection tubing set; in a second phase, passing said stored leukocyte enriched portion through an irradiation tubing set, including an irradiation chamber for photoactivating said reagent, until a predetermined level of photoactivation has been achieved; and in a third phase, returning said irradiated leukocyte enriched portion to said patient through a return tubing set. - View Dependent Claims (2, 3, 4, 5, 6)
-
Specification