Electronic control methods for puvapheresis apparatus
First Claim
1. In an extracorporeal patient treatment system for the photoactivation of a reagent in contact with the patient'"'"'s blood, said system including an anticoagulant infusion pump, a blood pump, a continuous centrifuge for obtaining various blood fractions, containers for receiving said fractions and for returning some fractions to the patient while other fractions are irradiated at an irradiation station, and sensors for generating signals in accordance with blood temperature, irradiation station cooling air flow and irradiation source current and voltage, a method for ensuring the safety of the patient undergoing treatment comprising:
- monitoring the temperature of the blood fraction to be irradiated as it enters and as it exits the irradiation station;
further monitoring the flow of cooling air supplied to said irradiation station;
additionally monitoring the current and voltage supplied to the radiation source associated with said irradiation station;
wherein said monitoring is performed on an analog basis whereby said analog signals are individually compared to preset thresholds so that said treatment system may be entirely halted if any of said thresholds is exceeded while, simultaneously, said monitoring is also performed on a digital basis, said sensor signals being converted to a digital basis by analog to digital converter means to enable digital monitoring by a microprocessor in accordance with preprogrammed software criteria communicated to said microprocessor.
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Accused Products
Abstract
Methods are provided for ensuring the safety of a patient undergoing extracorporeal treatment by irradiation of a photoactivatable reagent in contact with the patient'"'"'s blood including simultaneous digital and analog monitoring of temperature, voltage and current sensor signals. Also provided is a control system for controlling and regulating the various components of the photophoresis patient treatment system.
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Citations
4 Claims
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1. In an extracorporeal patient treatment system for the photoactivation of a reagent in contact with the patient'"'"'s blood, said system including an anticoagulant infusion pump, a blood pump, a continuous centrifuge for obtaining various blood fractions, containers for receiving said fractions and for returning some fractions to the patient while other fractions are irradiated at an irradiation station, and sensors for generating signals in accordance with blood temperature, irradiation station cooling air flow and irradiation source current and voltage, a method for ensuring the safety of the patient undergoing treatment comprising:
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monitoring the temperature of the blood fraction to be irradiated as it enters and as it exits the irradiation station; further monitoring the flow of cooling air supplied to said irradiation station; additionally monitoring the current and voltage supplied to the radiation source associated with said irradiation station; wherein said monitoring is performed on an analog basis whereby said analog signals are individually compared to preset thresholds so that said treatment system may be entirely halted if any of said thresholds is exceeded while, simultaneously, said monitoring is also performed on a digital basis, said sensor signals being converted to a digital basis by analog to digital converter means to enable digital monitoring by a microprocessor in accordance with preprogrammed software criteria communicated to said microprocessor.
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2. In an extracorporeal patient treatment system including means for withdrawing blood from said patient, adding an anticoagulation agent to said blood, pumping said blood to a continuous centrifuge for separating from said blood a leukocyte enriched portion having a predetermined volume, returning nonleukocyte enriched blood to the patient, irradiating the leukocyte enriched portion to a preset level of radiation whereby a photoactivatable reagent, in contact with said portion, is activated, and returning the thusly treated portion to said patient, a system for controlling the patient treatment system comprising:
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driver circuit means for controlling (1) valve servo motors for directing blood flow and (2) pump means for adding said anticoagulation agent; display circuit means for controlling status display and for receiving blood portion identification input; pump circuit means for controlling blood pump means for pumping blood through said patient treatment system; analog circuit means for controlling (1) power supply means for said centrifuge and (2) irradiation source and cooling power supply means, and for receiving signals generated by (1) irradiation cooling air flow sensor means, (2) blood temperature sensor means, and (3) centrifuge speed sensor means; alarm means for providing a warning if signals from said sensors fail to satisfy predetermined parameters; central control means electronically connected to said driver circuit means, said display circuit means, said pump circuit means, said analog circuit means, and said alarm means, said central control means further including memory means for storing programmed instructions and central processing means for regulating said various circuit means and alarm means in accordance with said instructions; and power supply means connected to said driver circuit means and said pump circuit means and said analog circuit means for supply power thereto, said power supply means including an isolation transformer for isolating said patient from power supplied to said patient treatment apparatus. - View Dependent Claims (3, 4)
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Specification