Method of calibrating and linearizing the output of fluid measuring instruments

• US 4,581,714 A
• Filed: 09/09/1983
• Issued: 04/08/1986
• Est. Priority Date: 09/09/1983
• Status: Expired due to Fees

• Current Assignee: Sensormedics Corporation (Becton, Dickinson & Co)
• Original Assignee: Sensormedics Corporation (Becton, Dickinson & Co)
• Inventors: Reid, Howard J.
• Primary Examiner(s): NOT, DEFINED
• Application Number:
  US06/530,551
• Time in Patent Office: 942 Days
• Field of Search: 364/571, 364/573, 364/581, 364/582
• US Class Current: 702/86
• CPC Class Codes: G01N 21/274 Calibration, base line adjustment, drift correction
• CPC Class Codes: G01N 21/37 using pneumatic detection opto-acoustic detection G01N21/1702
• CPC Class Codes: G01N 33/0006 Calibrating gas analysers

Abstract

A method for calibrating and linearizing the output of an instrument that includes a transducer having an output that is a nonlinear function of a property of interest of a fluid. The results of measurements performed on a plurality of transducers of the type to be used in the instrument are used to produce first and second equations which give the direct and inverse responses of a typical transducer. The results of further measurements on the particular transducer to be used in the instrument are used with the first equation to define how the second equation may be used to give accurate results with the particular transducer. The instrument is then calibrated and the results used with the second equation to produce an accurate linearized value for display as the output of the instrument.

Claims

1. A method of calibrating and linearizing the output of an instrument that includes a particular transducer having an output that is a non-linear function of a concentration of a component of interest in a fluid, comprising:

(a) producing a first equation which is characteristic of the output of a typical transducer of the type to be used in the instrument as a function of the concentration of the component of interest,

(b) producing a second equation which gives the concentration of the component of interest as a function of the output of said typical transducer,

(c) applying a first fluid having a known non-zero concentration of the component of interest to the particular transducer to be used in the instrument and measuring the actual output thereof,

(d) substituting a value corresponding to said known concentration into the first equation and evaluating the first equation to determine the estimated output of said typical transducer,

(e) using said actual and estimated outputs to determine the relative sensitivity of the particular transducer,

(f) applying a second fluid having a known nonzero concentration of the component of interest to the particular transducer and measuring the actual output thereof,

(g) correcting the measured output of step (f) for said relative sensitivity and using the result and the second equation to produce the linearized concentration value corresponding to the concentration of said second fluid,

(h) applying a sample fluid having an unknown concentration of the component of interest to the particular transducer and measuring the actual output thereof,

(i) correcting the measured output of step (h) for said relative sensitivity and using the result and the second equation to produce the linearized concentration value corresponding to the concentration of said sample fluid, and

(j) referencing the concentration value of step (i) to that of step (g) and displaying the result as the concentration of the component of interest in the sample fluid.

2. The method of claim 1 in which step (j) is performed by multiplying the ratio of said linearized concentration values by the concentration of the component of interest in the second fluid.

3. The method of claim 1 in which the first and second linearized concentration values are produced by substituting the corrected measured outputs produced in steps (g) and (i) into the second equation and then evaluating that equation.

4. The method of claim 1 in which the first and second linearized concentration values are produced by utilizing the second equation to construct a look-up table and then addressing said look-up table with the corrected measured outputs produced in steps (g) and (i).

5. The method of claim 1 in which said first and second fluids have the same concentration of the component of interest.

6. The method of claim 1 in which step (e) comprises taking the ratio K of said estimated output to said measured output.

7. The method of claim 6 in which the correcting steps of steps (g) and (i) comprise the multiplication of the measured output by ratio K.

8. The method of claim 1 in which at least one of the first and second equations is produced by:

(i) performing a pluraity of measurements on each of a plurality of transducers of the type to be used in the instrument,

(ii) selecting an equation of the type that is to be used in representing the response of a typical one of said transducer, said equation including at least one term with an unknown coefficient, and

(iii) determining the values of said coefficients which most closely fit said equation to the results of said plurality of measurements.

9. A method of calibrating and linearizing the output of an instrument that includes a particular transducer having an output that is a non-linear function of the concentration of a gas of interest, comprising:

(a) producing a first polynomial equation which is characteristic of the output of a typical transducer of the type to be used in the measurement as a function of the concentration of the gas of interest,

(b) producing a second polynomial equation which gives the concentation of the gas of interest as a function of the output of said typical transducer,

(c) applying a gas having substantially none of the gas of interest to the particular transducer to be used in the instrument, measuring the resulting output thereof, and storing that output for use as a zero correction value,

(d) applying a first gas having a first known nonzero concentration of the gas of interest to the particular transducer and measuring the actual output thereof,

(e) substituting a value corresponding to said first concentration into said first equation and evaluating the first equation to determine the estimated output of the typical transducer,

(f) subtracting the zero correction value from the actual output of the particular transducer to produce a zerocorrected actual output,

(g) using said estimated output and the zerocorrected actual output to determine the relative sensitivity of the actual transducer,

(h) applying a second gas having a second known non-zero concentration of the gas of interest to the particular transducer and measuring the actual output thereof,

(i) correcting the measured output of step (h) for the zero correction value and said relative sensitivity, and using the result and the second equation to produce the linearized concentration value corresponding to said second concentration,

(j) applying a sample gas having an unknown concentration of the gas of interest to the particular transducer and measuring the actual output thereof,

(k) correcting the measured output of step (j) for the zero correction value and said relative sensitivity, and using the result and the second equation to produce the linearized concentration value corresponding to said unknown concentration, and

(l) producing an output signal that is indicative of the ratio of said linearized concentration values and said second concentration.

10. The method of claim 9 in which the first and second linearized concentration values of steps (i) and (k) are produced by substituting the zero-corrected measured output values into the second equation and then evaluating the same.

11. The method of claim 9 in which the linearized concentration values of steps (i) and (k) are produced with reference to a look-up table constructed by evaluating the second equation for a plurality of assumed output values.

12. The method of claim 9 in which the first and second gases are the same gas.

13. The method of claim 9 in which the second equation is multiplied by a scaling factor prior to its use in steps (i) and (k), said scaling factor being a number which assures that the signal processing capacity of the instrument is not exceeded when the transducer produces its maximum output.

14. A method of calibrating and linearizing the output of an instrument that includes a particular transducer having an output V that is a non-linear function of the magnitude C of a property of interest of a fluid, comprising:

(a) performing a series of measurements on each of a plurality of transducers of the type to be used in the instrument,

(b) selecting a first equation V=f₁ (C) of a type that is suitable for use in representing the response of a typical one of said transducers, where f₁ is a first function having at least one unknown coefficient,

(c) selecting a second equation C=f₂ (V) of a type that is suitable for use in representing the inverse response of the typical one of said transducers, where f₂ is a second function having at least one unknown coefficient,

(d) determining the values of the unknown coefficients of the first function to adapt said first equation to represent the response of the typical transducer,

(e) determining the values of the unknown coefficients of the second function to adapt said second equation to represent the inverse response of the typical transducer,

(f) applying to the particular transducer a fluid having substantially a zero magnitude of the property of interest and measuring the output V_o thereof,

(g) applying to the particular transducer a first fluid having a first known magnitude C_s1 of the property of interest and measuring the actual output V_sa thereof,

(h) substituting C_s1 into the first equation and evaluating the first equation to determine the estimated output V_se of said particular transducer,

(i) determining the ratio K of V_se to V_sa -V_o,

(j) applying to the particular transducer a second fluid having a second known magnitude C_s2 of the property of interest and measuring the actual output V_c thereof,

(k) using the second equation to determine the value of C_c, which corresponds to V=K (V_c -V_o),

(l) applying to the particular transducer a fluid having an unknown magnitude of the property of interest and measuring the actual output V_u thereof,

(m) using the second equation to determine the value C_u which corresponds to V=K (V_u -V_o) and

(n) producing as an output a signal indicative of the value C_out, where C_out =C_u (C_s2 /C_c).

15. The method of claim 14 in which the first fluid is

the same as the second fluid.

16. The method of claim 14 in which values C_c and C_u are determined with reference to a look-up table constructed by evaluating the second equation for a plurality of assumed values of V.

17. The method of claim 14 in which values C_c and C_u are determined by evaluating the second equation for the values V=K (V_c -V_o) and V=K (V_u -V_o), respectively.

18. The method of claim 14 in which the second equation is multiplied by a scaling factor K'"'"' prior to its use in steps (j) and (l), K'"'"' being a number which assures that the signal processing capacity of the instrument is not exceeded when the transducer produces its maximum output.

19. A method of calibrating and linearizing the output of an instrument that includes a particular transducer having an output V that is a non-linear function of the magnitude C of a property of interest of a fluid, comprising:

(a) performing a series of measurements on each of a plurality of transducers of the type to be used in the instrument,

(b) selecting a first equation V=f₁ (C) of a type that is suitable for use in representing the response of a typical one of said transducers, where f₁ is a first function having at least one term with an unknown coefficient,

(c) selecting a second equation C=f₂ (V) of a type that is suitable for use in representing the inverse response of the typical one of said transducers, where f₂ is a second function having at least one term with an unknown coefficient,

(d) determining the values of the unknown coefficients of the first function to adapt said first equation to represent the response of the typical transducer,

(e) determining the values of the unknown coefficients of the second function to adapt said second equation to represent the inverse response of the typical transducer,

(f) applying a fluid for which C is substantially equal to zero to the particular transducer and measuring and storing the resulting output V_o thereof,

(g) applying to the particular transducer a first fluid having a first known magnitude C_s1 of the property of interest and measuring the actual output V_sa thereof,

(h) substituting C_s1 into the first equation and evaluating the first equation to determine the estimated output V_se of said typical transducer,

(i) determining the ratio K=V_se /(V_sa -V_o),

(j) evaluating the second equation for C_max =f₂ (KV_max) where V_max is the maximum output of the typical transducer,

(k) determining the ratio

space="preserve" listing-type="equation">K'"'"'=0.95 (V.sub.cap)/C.sub.max

where V_cap is the maximum V value which can be handled by the instrument,

(l) reformulating the second equation as

space="preserve" listing-type="equation">C=K'"'"'f.sub.2 (K[V-V.sub.o ]),

(m) applying to said particular transducer a second fluid having a second known magnitude C_s2 of the property of interest and measuring the output V_c thereof,

(n) using the reformulated second equation to determine the linearized value C_c which corresponds to V=V_c,

(o) applying to the particular transducer a sample fluid having an unknown magnitude of the property of interest and measuring the output V_u thereof,

(p) using the reformulated second equation to determine the value C_u which corresponds to V=V_u, and

(q) producing as an output a signal indicative of the value C_out where C_out =C_u (C_s2 /C_c).

20. The method of claim 19 in which said first and second fluids have the same magnitude of the property of interest.

21. The method of claim 19 in which steps (n) and (p) are performed by substituting the measured outputs into the reformulated second equation and then evaluating the same.

22. The method of claim 19 in which steps (n) and (p) are performed by referencing a look-up table constructed by evaluating the reformulated second equation for a plurality of assumed values of V.