Measuring device for determining the O.sub.2 content of a sample

• US 4,587,101 A
• Filed: 11/18/1983
• Issued: 05/06/1986
• Est. Priority Date: 11/22/1982
• Status: Expired due to Term

• Current Assignee: AVL AG Grabenstrasse 11 Schaffhausen
• Original Assignee: AVL AG
• Inventors: Kroneis, Herbert, Marsoner, Hermann
• Primary Examiner(s): Lesmes, George F.
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US06/553,386
• Time in Patent Office: 900 Days
• Field of Search: 428/690, 250/462.1, 252/408.1, 422/52, 422/56, 436/136, 436/138, 436/172
• US Class Current: 422/421
• CPC Class Codes: C09K 11/02 Use of particular materials as binders, particle coatings or suspension media therefor
• CPC Class Codes: C09K 11/025 non-luminescent particle coatings or suspension media
• CPC Class Codes: C09K 11/06 containing organic luminescent materials
• CPC Class Codes: G01N 21/6428 Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" in vivo A61B5/00; immunoassay G01N33/53
• CPC Class Codes: G01N 21/643 non-biological material

Abstract

In a sensor element for determining the O₂ content of a sample, comprising a fluorescent indicator substance which is embedded in a polymer carrier and with which the sample may be brought into contact, a fluorescence extinction sufficiently high for yielding useful measurement results is achieved by the use of plasticizer-compatible polymers as carrier materials which contain plasticizers in addition to the indicator molecules.

Claims

1. A sensor element which, when placed in contact with a sample containing oxygen, is capable of indicating the oxygen content in said sample, said sensor element comprising a carrier which is composed of a linear and amorphous polymer which is compatible with plasticizers, said polymer carrier being permeable to oxygen molecules;

a plasticizer compound contained within said polymer carrier; and

an oxygen-sensitive fluorescent indicator substance selected from the group consisting of polycyclic aromatic molecules, homocyclic aromatic molecules and heterocyclic aromatic molecules contained within said polymer carrier, said oxygen-sensitive fluorescent indicator substance upon excitation emitting light of a certain wavelength and of varying intensity depending on the amount of oxygen from said sample in contact therewith.

2. A sensor element according to claim 1, wherein said carrrier is composed of hydrophilic polymers selected from the group consisting of cellulose acetate, cellulose acetate butyrate, cellulose nitrate and ethyl cellulose, and wherein said plasticizers are selected from the group consisting of glycol, glycerin and pentaerythrite.

3. A sensor element according to claim 1, wherein said carrier is composed of hydrophobic polymers selected from the group consisting of polyvinylchloride, polystrene, polyvinyllacetate, polyvinyl butyral, polyvinyl chloride acetate, polyethylene, polypropylene, polyurethane, polyester, natural rubber, isoprene rubber, chloroprene rubber and butyl rubber, and wherein said plasticizers are selected from the group consisting of high-boiling esters, mineral oils, chlorinated biphenyls, chlorinated polyphenyls, epoxidized oils, polymeric plasticizers, and polymerizable plasticizers.

4. A sensor element according to claim 3, wherein said high-boiling esters are selected from the group consisting of triarylphosphates, dialkylphthalates, dialkyladipates and dialkylsebacates.

5. A sensor element according to claim 3, wherein said polymeric plasticizers are selected from the group consisting of polyester, polyisobutane and nitride rubber.

6. A sensor element according to claim 3, wherein said polymerizable plasticizers are selected from the group consisting of alkyl ester, aryl ester and nitride ester.

7. A sensor element according to claim 1, wherein said fluorescent indicator substance comprises a polycyclic aromatic hydrocarbon which displays fluorescence decay times τ

_o greater than 5 ns.

8. A sensor element according to claim 1, wherein said polymer carrier defines a side which is intended to face the sample containing oxygen, and wherein said sensor element includes an additional layer of polymer of low transparency which is applied on said side of said polymer carrier.

9. A sensor element according to claim 8, wherein said additional layer has the same composition as said carrier and wherein it incorporates particles of ferrous oxide.

10. A sensor element according to claim 1, further including pigment particles in said polymer carrier.

11. A sensor element according to claim 10, wherein said pigment particles comprise ferrous oxide particles.

12. A sensor element according to claim 10, wherein said pigment particles are accumulated on the side of said polymer carrier facing said sample due to the influence of external fields of force, such as gravitational, electric or magnetic fields.

13. A sensor element according to claim 1, wherein said polymer carrier defines a side which is intended to face the sample containing oxygen, and wherein said sensor element includes a thin mesh screen embedded in said side of said polymer carrier.

14. A sensor element according to claim 1, wherein said fluorescent indicator substance includes hydrocarbon chains containing between 3 and 20 carbon atoms, such that the mobility of said fluorescent indicator substance in said polymer carrier is reduced.

15. A sensor element according to claim 1, wherein said fluorescent indicator substance is covalently bonded to said polymer carrier to immobilize it within said carrier.