Microencapsulated astringent hemostatic agents and methods of use
First Claim
1. A granular composition for producing capillary hemostasis, comprising:
- a granular astringent hemostatic agent selected from the group consisting of ferric and aluminum inorganic salts encapsulated with a cellulose-based biocompatible polymer soluble in body fluids.
0 Assignments
0 Petitions
Accused Products
Abstract
An astringent hemostatic composition comprised of a micron-sized astringent hemostatic agent microencapsulated in a biocompatible and non-allergenic hemostatic polymer soluble in body fluids. The composition may be used intraorally or dermatologically. For intraoral purposes, the preferred composition is ferric sulfate microencapsulated in ethyl cellulose material. The composition of the invention may be used in a method for effecting gingival retraction. In the method, the microencapsulated astringent hemostatic composition is introduced into the gingival sulcus and is compacted by the patient biting onto bite registration material. A plurality of different microencapsulated astringent hemostatic agents having different time-release properties may be assembled in a kit form allowing a practitioner to formulate a specific formulation designed to treat a specific injury or condition.
An astringent hemostatic composition of the invention may be used in a bandage for covering a wound. In one bandage embodiment, the gauze or sponge pad is sprayed with a biocompatible adhesive onto which a dusting of astringent hemostatic composition of the invention is applied. In a second bandage embodiment, a layer or dusting of astringent hemostatic composition of the invention is sandwiched between an upper and lower gauze or sponge layer. In a third bandage embodiment, an astringent hemostatic composition of the invention is adhered to a transdermal bandage using a biocompatible adhesive.
-
Citations
12 Claims
-
1. A granular composition for producing capillary hemostasis, comprising:
a granular astringent hemostatic agent selected from the group consisting of ferric and aluminum inorganic salts encapsulated with a cellulose-based biocompatible polymer soluble in body fluids. - View Dependent Claims (2, 3, 4, 5)
-
6. A composition for producing capillary hemostasis comprised of a blend in the proportions as follows:
-
particles of astringent hemostatic agent selected from the group consisting of ferric sulfate, aluminum sulfate, and aluminum chloride encapsulated with cellulose-based materials selected from the group consisting of ethyl cellulose, methyl cellulose, oxycellulose, and oxidized cellulose 82-100% and; particles of epinephrine encapsulated with cellulose-base materials selected from the group consisting of ethyl cellulose, methyl cellulose, oxycellulose, and oxidized cellulose 0-18%.
-
-
7. A composition for producing capillary hemostasis comprised of a blend in the percentages as follows:
-
particles of astringent hemostatic agent selected from the group consisting of ferric sulfate, aluminum sulfate, and aluminum chloride encapsulated with cellulose-based materials selected from the group consisting of ethyl cellulose, methyl cellulose, oxycellulose, and oxidized cellulose about 92% and, particles of epinephrine encapsulated with cellulose-based materials selected from the group consisting of ethyl cellulose, methyl cellulose, oxycellulose, and oxidized cellulose remainder 8%.
-
-
8. A composition for producing capillary hemostasis, comprising:
-
particles of astringent hemostatic agents selected from the group consisting of ferric sulfate, aluminum sulfate, and aluminum chloride encapsulated with cellulose-base materials selected fom the group consisting of ethyl cellulose, methyl cellulose, oxycellulose and oxidized cellulose; said particles suspended in a liquid carrier which does not dissolve said encapsulation material.
-
-
9. A composition for producing capillary hemostasis, comprising:
a granular astringent hemostatic agent selected from the group consisting of ferric and aluminum inorganic salts encapsulated with a cellulose-based biocompatible hemostatic polymer soluble in body fluids.
-
10. A granular composition for producing capillary hemostasis, comprising:
a granular hemostatic agent selected from the group consisting of ferric and aluminum inorganic salts encapsulated with ethyl cellulose having hemostatic properties.
-
11. A granular composition for producing capillary hemostasis, comprising:
a granular astringent hemostatic agent selected from the group consisting of ferric and aluminum inorganic salts encapsulated with a cellulose-based biocompatible polymer absorbable in body fluids.
-
12. A composition for producing capillary hemostasis, comprising:
a granular astringent hemostatic agent selected from the group consisting of ferric and aluminum inorganic salts encapsulated with a cellulose-based biocompatible hemostatic polymer absorbable in body fluids.
Specification