Two-component syringe assembly

• US 4,599,082 A
• Filed: 08/13/1984
• Issued: 07/08/1986
• Est. Priority Date: 08/13/1984
• Status: Expired due to Term

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Grimard, Jean P.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Kaechele, Karen
• Application Number:
  US06/640,434
• Time in Patent Office: 694 Days
• Field of Search: 604/82, 604/89, 604/90, 604/191, 604/218, 604/236, 604/238, 604/187, 215/6, 215/355
• US Class Current: 604/90
• CPC Class Codes: A61M 2005/3104 Caps for syringes without needle
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/31513 Piston constructions to improve sealing or sliding
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing

Abstract

A two-component syringe includes a barrel having a chamber for retaining fluid and a distal end of the barrel having a passageway therethrough communicating with the chamber. A by-pass stopper is slidably positioned in fluid-tight engagement inside the barrel. The stopper has a distal rib contacting the barrel, a recess on the proximal side of the rib and a groove in the rib for allowing fluid communication between the recess and the chamber. This groove is positioned angularly with respect to the longitudinal access of the barrel so that liquid passing therethrough is directed angularly with respect to the longitudinal axis of the barrel. The barrel also includes a raised peripheral portion serving as a by-pass and defining a by-pass zone. The by-pass zone is shorter than the length of the stopper along the longitudinal axis of the barrel. The by-pass is sufficiently long and raised enough to allow liquid to flow around the stopper between the proximal end of the stopper and the recess when the proximal end of the stopper is positioned in the by-pass zone. Also included is a piston slidably positioned in fluid-tight engagement inside the barrel. This piston is adapted to engage a plunger rod to facilitate its operation.

Claims

1. A two-component mixing syringe comprising:

an elongate, hollow barrel having a chamber for retaining the components;

a tip extending from a distal end of said barrel having a passageway therethrough communicating with said chamber;

a by-pass stopper slidably positioned in fluid-tight engagement inside said barrel having a distal rib contacting said barrel, said stopper having a recess on the proximal side of said rib and a groove in said rib, said groove allowing fluid communication between said recess and said chamber and positioned angularly with respect to the longitudinal axis of said barrel so that fluid passing through said groove is directed angularly with respect to the longitudinal axis of said barrel;

a raised peripheral portion of said barrel serving as a by-pass and defining a by-pass zone, said by-pass zone being shorter than the length of said by-pass stopper along the longitudinal axis of said barrel, said by-pass being sufficiently long and raised to allow fluid to flow around said stopper between the proximal end of said stopper and said recess when the proximal end of said stopper is positioned in said by-pass zone; and

a piston slidably positioned in fluid-tight engagement inside said barrel adapted to engage a plunger rod to facilitate its operation, said piston capable of moving fluid from said chamber through said passageway upon its movement toward said distal end, said piston capable of facilitating the drawing of fluid into said chamber through said passageway upon its movement away from said distal end.

2. The syringe of claim 1 wherein said groove is oriented at an angle within the range of about 30°

to 80°

with respect to the longitudinal axis of said barrel.

3. The syringe of claim 1 wherein said recess forms a continuous channel around the periphery of said stopper.

4. The syringe of claim 3 wherein there is a plurality of grooves all being in fluid communication with said recess.

5. The syringe of claim 4 wherein said grooves are substantially equally spaced from each other along the periphery of said distal rib.

6. The syringe of claim 1 further including at least one proximal rib on the proximal side of said recess contacting said barrel.

7. The syringe of claim 1 wherein said by-pass is positioned so that when said recess is in fluid communication with said by-pass and said distal rib is positioned outside of said by-pass zone, the volume defined within said chamber between said stopper and said distal end of said barrel is approximately the volume of the combined components.

8. The syringe of claim 1 wherein said by-pass is raised in an outwardly direction from said barrel.

9. The syringe of claim 1 further including sealing means for releasably sealing said passageway.

10. The syringe of claim 9 wherein said sealing means includes a tip cap removably held by said tip.

11. The syringe of claim 9 further including a first component in said chamber between said by-pass stopper and said piston, a second component in said chamber between said by-pass stopper and said distal end of said barrel, said by-pass stopper being positioned outside of said by-pass zone adjacent to the proximal end of said by-pass.

12. The syringe of claim 11 wherein said second component is a material selected from the group of medications consisting of liquid, powder, solids or combinations thereof.

13. The syringe of claim 1 wherein said by-pass stopper and said piston are made from material selected from the group consisting of natural rubber, synthetic rubber and thermoplastic elastomers.

14. The syringe of claim 1 further including a plunger rod engaged to said piston and extending outwardly from the proximal end of said barrel.

15. A two-component syringe comprising:

a barrel having a chamber for retaining fluid;

a distal end of said barrel having a passageway therethrough communicating with said chamber;

a by-pass stopper slidably positioned in fluid-tight engagement inside said barrel having a distal rib, said stopper having a recess on the proximal side of said rib and fluid communication means in said rib for allowing fluid communication between said recess and said chamber, said fluid communication means being positioned so that fluid passing therethrough is directed angularly with respect to the longitudinal axis of said barrel;

by-pass means for allowing fluid to flow around said stopper between the proximal end of said stopper and said recess; and

piston means slidably positioned in fluid-tight engagement inside said barrel capable of engaging a plunger rod to facilitate its operation, said piston means capable of moving fluid from said chamber through said passageway upon its movement toward said distal end, said piston means capable of facilitating the drawing of fluid into said chamber through said passageway upon its movement away from said distal end.

16. The syringe of claim 15 wherein said fluid communication means is a groove.

17. A two-component medication syringe comprising:

an elongate substantially cylindrical barrel having a chamber for retaining fluid;

a tip extending from a distal end of said barrel having passageway therethrough communicating with said chamber, said tip having means for accepting a hypodermic needle;

releasable sealing means associated with said tip for sealing said passageway;

a by-pass stopper slidably positioned in fluid-tight engagement inside said barrel having a distal rib contacting said barrel, said stopper having a recess on the proximal side of said distal rib and a groove in said distal rib, said groove allowing fluid communication between said recess and said chamber, said groove positioned angularly with respect to the longitudinal axis of said barrel so that liquid passing through said groove is directed angularly with respect to the longitudinal axis of said barrel said stopper having at least one proximal rib on the proximal side of said recess contacting said barrel;

a raised peripheral portion of said barrel serving as a by-pass and defining a by-pass zone, said by-pass zone being shorter than the length of said by-pass stopper along the longitudinal axis of said barrel, said by-pass being sufficiently long and raised to allow liquid to flow around said by-pass stopper between the proximal end of said stopper and said recess when the proximal end of said stopper is positioned in said by-pass zone;

a piston slidably positioned in fluid-tight engagement inside said barrel adapted to engage a plunger rod to facilitate its operation, said piston capable of moving fluid from said chamber through said passageway upon its movement toward said distal end, said piston capable of facilitating the drawing of fluid into said chamber through said passageway upon its movement away from said distal end;

a first component of liquid medication contained within said chamber between said stopper and said piston, said stopper being positioned outside said by-pass zone adjacent to the proximal end of said by-pass; and

a second component of medication substantially within said chamber between said stopper and said distal end of said barrel.

18. The syringe of claim 17 wherein said groove is oriented at an angle within the range of about 30°

to 80°

with respect to the longitudinal axis of said barrel.

19. The syringe of claim 18 wherein said recess forms a continuous channel around the periphery of said stopper.

20. The syringe of claim 19 wherein there is a plurality of grooves all being in fluid communication with said recess.

21. The syringe of claim 20 wherein said grooves are substantially equally spaced from each other along the periphery of said distal rib.

22. The syringe of claim 17 wherein said bypass is positioned so that when said recess is in fluid communication with said by-pass and said distal rib is positioned outside of said by-pass zone, the volume defined within said chamber between said stopper and said distal end of said barrel is approximately the volume of the combined components of the medication.

23. The syringe of claim 17 wherein said second component of medication is selected from the group of medications consisting of liquid, solid and powder.

24. A by-pass stopper for use in a syringe having a substantially cylindrical barrel comprising:

a piston-like body for slidable fluid tight engagement inside the barrel of a syringe having a first end, a second end and a longitudinal axis therethrough;

an annular rib at said first end and an annular rib at said second end of said body, said body having an annular recess between said ribs with a diameter less than the diameter of each of said ribs; and

said rib at said first end having a plurality of grooves for allowing fluid communication therethrough, said grooves being positioned angularly with respect to said longitudinal axis.

25. The stopper of claim 24 further including a second rib adjacent to the rib on said second end of said body, said second rib having an outside diameter greater than the diameter of said recess.

26. The stopper of claim 24 wherein said grooves are oriented at an angle within the range of about 30°

to 80°

with respect to said longitudinal axis.