Bone implant member for prostheses and bone connecting elements and process for the production thereof

• US 4,599,085 A
• Filed: 02/01/1984
• Issued: 07/08/1986
• Est. Priority Date: 07/11/1979
• Status: Expired due to Fees

• Current Assignee: Neodontics, Inc.
• Original Assignee: Neodontics, Inc.
• Inventors: Geiger, Albert, Riess, Guido
• Primary Examiner(s): Frinks, Ronald L.
• Application Number:
  US06/575,696
• Time in Patent Office: 888 Days
• Field of Search: 3/1.9-1.913, 128/92 C, 128/92 CA, 128/92 B, 433/173-176, 433/201, 623/16-23
• US Class Current: 424/422
• CPC Class Codes: A61B 17/58 for osteosynthesis, e.g. bone plates, screws , setting implements or the like A61B17/14, A61B17/16 take precedence
• CPC Class Codes: A61C 8/0012 characterised by the material or composition, e.g. ceramics, surface layer, metal alloy use of specific materials A61K6/00
• CPC Class Codes: A61C 8/0013 with a surface layer, coating
• CPC Class Codes: A61F 2/30767 Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
• CPC Class Codes: A61F 2/3662 Femoral shafts
• CPC Class Codes: A61F 2002/30405 made by screwing complementary threads machined on the parts themselves
• CPC Class Codes: A61F 2002/3085 with a threaded, e.g. self-tapping, bone-engaging surface, e.g. external surface
• CPC Class Codes: A61F 2002/30929 having at least two superposed coatings
• CPC Class Codes: A61F 2002/30968 Sintering
• CPC Class Codes: A61F 2220/0025 Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
• CPC Class Codes: A61F 2310/00017 Iron- or Fe-based alloys, e.g. stainless steel
• CPC Class Codes: A61F 2310/00023 Titanium or titanium-based alloys, e.g. Ti-Ni alloys
• CPC Class Codes: A61F 2310/00149 Platinum or Pt-based alloys
• CPC Class Codes: A61F 2310/00155 Gold or Au-based alloys
• CPC Class Codes: A61F 2310/00796 Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
• CPC Class Codes: A61L 2430/02 for reconstruction of bones; weight-bearing implants
• CPC Class Codes: A61L 27/32 Phosphorus-containing materials, e.g. apatite
• CPC Class Codes: Y10T 428/12153 Interconnected void structure [e.g., permeable, etc.]

Abstract

A bone implant member for bone, joint, as well as dental prostheses, bone connecting elements such as bone screws and splints, which consists of a mechanically stable carrier material compatible (biocompatible) with bone tissue and of bioactive calcium phosphate ceramic, in particular tri- and tetracalcium phosphate, as well as a process for the production of such an implant member.

Claims

1. A bone implant member capable of being used for bones, joints, dental prosthesis, bone screws and splints, and other bone connecting elements, said bone implant member being fashioned at least in part of a compound consisting essentially of a substantially homogeneous sintered mixture of:

(a) a bioreactive, particulate calcium phosphate ceramic, said ceramic consisting essentially of a mixture of tricalcium phosphate and tetracalcium phosphate; and

(b) a biocompatible, mechanically stable, particulate metal;

wherein the bone implant member is formed by admixing the particulate calcium phosphate ceramic and the particulate metal and bonding the particulate calcium phosphate ceramic and the particulate metal by sintering under high pressure whereby the particulate metal is substantially homogenously distributed throughout the sintered bone implant member.

2. A bone implant member as defined in claim 1 further comprising:

a layer of substantially pure calcium phosphate formed on at least a portion of the outer surface of the bone implant member, said layer of calcium phosphate being anchored to the bone implant member by a bond formed between the calcium phosphate layer and the particulate calcium phosphate ceramic of the member.

3. A bone implant member as defined in claim 2 wherein the particulate calcium phosphate ceramic particles and the particulate metal particles are substantially equal in size and are mixed together in substantially equal volumetric portions.

4. A bone implant member as defined in claim 2 wherein the particulate metal is selected from the group consisting of titanium, platinum, gold, and stainless steel.

5. A bone implant member as defined in claim 2 wherein the particulate metal is selected from the group consisting of tantalum and niobium.