Single-needle artificial kidney

• US 4,599,165 A
• Filed: 01/14/1985
• Issued: 07/08/1986
• Est. Priority Date: 01/18/1984
• Status: Expired due to Term

• Current Assignee: Hospal Industrie
• Original Assignee: Hospal Industrie
• Inventors: Chevallet, Jacques
• Primary Examiner(s): Sever, Frank
• Application Number:
  US06/691,492
• Time in Patent Office: 540 Days
• Field of Search: 210/321.3, 210/85, 210/87, 210/97
• US Class Current: 210/87
• CPC Class Codes: A61M 1/1649 with pulsatile dialysis fluid flow
• CPC Class Codes: A61M 1/30 Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/303 having a reservoir for treated blood to be returned
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 2230/06 Heartbeat rate only

Abstract

A single-needle artificial kidney comprising a haemodialyser divided by a semi-permeable membrane into first and second compartments, one of which forms part of an extracorporeal blood circuit including a blood circulation pump and a single needle for inserting into the patient and a dialysis liquid circuit including the second chamber and a dialysis liquid pump. The dialysis liquid circuit is provided with means for periodically modulating the flow rate of the dialysis liquid in the haemodialyser between minimum and maximum values, the flow rate of the dialysis liquid being produced by a sensing pulsations of the blood at frequencies less than one hertz and using these pulsations via a servo-control to effect changes in the dialysis liquid flow rate so that it reaches maximum and minimum values simultaneously with maximum and minimum of the blood flow rate.

Claims

1. An artificial kidney which includes a haemodialyser (13) a semi-permeable membrane (14) which can effect dialysis and ultrafiltration of the blood, said diaphragm dividing said haemodialyser into first and second compartments (28), (29) an extracorporeal blood circuit including said first compartment (28), a blood circulation pump (15, 16) and a single needle (12) for insertion into the patient (11), a dialysis liquid circuit including said second compartment (29) and a dialysis liquid pump (27), characterized in that said dialysis liquid circuit includes means for enabling simultaneous pulsing of both blood and dialysis liquid in the haemodialyser of said single-needle artificial kidney, sufficient to provide the high efficiencies otherwise obtained with conventional double-needle artificial kidneys, including means (27a, 27b,27c,27d,27e) for periodically modulating the flow rate of said dialysis liquid in the said haemodialyser (13) between minimum and maximum values, a sensor (17) sensitive to the pulsation of the blood in said extracorporeal blood circuit at a frequency below 1 hertz, and a servo-control (28a,28b, 28c,28d) operable in response to said sensor to control said means for periodically modulating the flow of dialysis liquid as a function of said pulsations of the blood at frequencies below 1 hertz.

2. An artificial kidney according to claim 1, characterized in that the said means for periodically modulating the flow (27a,27b,27c,27d,27e) of the dialysis liquid, are synchronized through the servo-control (28a,28b, 28c,28d) to a sensor (15, 16, 17) which is sensitive to the pulsations of the blood, whereby the flow rates of blood and dialysis liquid are simultaneously at the maximum and minimum values in the haemodialyser (13).

3. An artificial kidney according to claim 1 or 2, characterised in that said means for periodically modulating the flow rate of dialysis liquid act at a frequency which is substantially constant and between 0.1 and 1 hertz.

4. An artificial kidney according to any one of the preceding claims, characterised in that the flow rate of the dialysis liquid is modulated between 100 and 1000 ml per min.

5. An artificial kidney according to any one of the preceding claim, characterised in that said sensor is situated in the extracorporeal blood circuit at a point (17) close to said haemodialyser (13).

6. An artificial kidney according to any one of the preceding claim, characterized in that said means for modulating the flow rate of the dialysis liquid comprise a multi-speed volumetric circulation pump (27a) operated intermittently by the said servo-control (28a).

7. An artificial kidney according to any one of claims 1 to 4 characterized in that said sensor is a blood circulation pump (15, 16) in said extracorporeal blood circuit.

8. An artificial kidney according to any one of claims 1 to 7, characterized in that said means for periodically modulating the flow rate of the dialysis liquid comprise a by-pass duct (30b), (30c) arranged in parallel with respect to said dialysis liquid circuit, a valve (29b, 29c) provided with a closure member said valve being situated in said by-pass duct, the position of said closure member being operated intermittently by said servo-control (28b,28c).

9. An artificial kidney according to any one of claims 1 to 7, characterized in that said means for periodically modulating the flow rate of the dialysis liquid comprises two circulation pumps (27d,27e) arranged in parallel at least one of which is periodically operated by said servo-control (28d).