Method for dialysis

• US 4,601,830 A
• Filed: 10/28/1981
• Issued: 07/22/1986
• Est. Priority Date: 11/19/1979
• Status: Expired due to Fees

• Current Assignee: The United States of America As Represented By The Secretary of Agriculture
• Original Assignee: The United States of America As Represented By The Secretary of Agriculture
• Inventors: Chen, Wei-Tzuoh
• Primary Examiner(s): SPEAR JR, FRANK
• Application Number:
  US06/315,668
• Time in Patent Office: 1,728 Days
• Field of Search: 210/96.2, 210/321.3, 210/647
• US Class Current: 210/647
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates

Abstract

A method and apparatus for the hemodialysis of the blood of kidney failure patients. The concentration of the dialysis solution is initially selected so that the solution osmolality approximates the osmolality of the patient'"'"'s blood. The dialysis solution concentration is then reduced linearly as a function of time as the dialysis is carried out. The conductivity of the dialysis solution is measured and compared with high and low limit references. If the conductivity is outside the limits, an alarm is given and the concentration of the dialysis solution is held constant. A timer controls a proportional pumping means to reduce the concentration of the dialysis solution and concurrently reduces the conductivity reference limits for the alarm.

Claims

1. In the hemodialysis of blood by circulation of a dialysis solution in molecular exchange relation with blood to reduce the osmolality of the blood, the improvement comprising:

initiating the hemodialysis with a dialysis solution having an osmolality of the order of the osmolality of the patient'"'"'s blood; and

thereafter varying the osmolality of the dialysis solution as a function of time to achieve the desired osmolality for the patient'"'"'s condition.

2. The hemodialysis method of claim 1 in which the osmolality of the dialysis solution is reduced continuously with time.

3. The hemodialysis method of claim 1 including the steps:

establishing upper and lower conductivity limits for the dialysis solution;

varying both limits in accordance with the variation of the conductivity of the dialysis solution as the osmolality thereof is changed; and

initiating an alarm in the event the conductivity of the dialysis solution is outside said upper and lower conductivity limits.

4. The hemodialysis method of claim 3 in which the osmolality of the dialysis solution is reduced linearly with time and the upper and lower conductivity limits are reduced linearly with time.

5. In the hemodialysis of blood by circulation of a dialysis solution in molecular exchange relation with blood to reduce the osmolality of the blood, the improvement comprising:

mixing a concentrated dialysis solution with water for circulation of the dialysis solution mixture through a dialyzer;

establishing an initial concentration of said dialysis solution mixture having an osmolality of the order of the osmolality of the patient'"'"'s blood;

reducing the concentration of the dialysis solution mixture as a function of time;

measuring the conductivity of the dialysis solution mixture;

establishing initial upper and lower conductivity limits;

reducing said upper and lower conductivity limits as a function of time;

comparing the dialysis solution mixture conductivity with said upper and lower conductivity limits; and

initiating an alarm if the dialysis solution mixture conductivity is below the lower limit or above the upper limit.

6. The hemodialysis method of claim 5 in which the concentration of the dialysis solution mixture and the upper and lower conductivity limits are reduced continuously as a function of time.