Arterial graft prosthesis

• US 4,604,762 A
• Filed: 02/13/1981
• Issued: 08/12/1986
• Est. Priority Date: 02/13/1981
• Status: Expired due to Term

• Current Assignee: TC1 LLC (Abbott Laboratories Incorporated)
• Original Assignee: Thoratec Laboratories Corp. (Thoratec LLC)
• Inventors: Robinson, Thomas C.
• Primary Examiner(s): FRINKS, RONALD
• Application Number:
  US06/234,116
• Time in Patent Office: 2,006 Days
• Field of Search: 3/1.4, 3/1, 3/1.5, 128/334 R
• US Class Current: 623/1.44
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/826 more than one stent being applied sequentially
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/507 for artificial blood vessels apparatus for applying cells on a blood vessel prosthesis A61F2/062
• CPC Class Codes: C08L 75/00 Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers

Abstract

An arterial graft prosthesis comprises a first interior zone of a solid, segmented polyether-polyurethane material surrounded by a second zone of a porous, segmented, polyether-polyurethane and a third zone immediately surrounding said second zone and of a solid, segmented polyether-polyurethane. The interior zone may have a lining or blood interface of a microporous zone of segmented polyether-polyurethane, and the exterior, third zone may be surrounded by a tissue interface of a microporous zone of segmented polyether-polyurethane. In some instances the exterior may be confined by a tube of substantially non-stretchable netting fastened in place at chosen, spaced intervals or other forms of reinforcement may be employed. Other materials can be used.

Claims

1. An arterial graft prosthesis formed of a core zone of porous elastomer disposed about the longitudinal axis of the prosthesis, an inner zone of solid elastomer concentric with and homogeneously joined to the inside of said core zone, an outer zone of porous elastomer, said outer zone of porous elastomer being concentric with and homogeneously joined to the outside of said core zone.

2. An arterial graft prosthesis as defined in claim 1, together with a blood interface zone of microporous elastomer concentric with and homogeneously joined to the inside of said inner zone of solid elastomer.

3. An arterial graft prosthesis as defined in claim 2 wherein said blood interface zone defines pores having a diameter and depth of from 5 to 100 microns.

4. An arterial graft prosthesis as defined in claim 2 wherein the surface of said blood interface zone is hydrophilic.

5. An arterial graft prosthesis as defined in claim 4 wherein the surface of said blood interface zone is coated with an antithrombin.