Method for the elimination or the enlargement of points of constriction in vessels carrying body fluids

• US 4,610,662 A
• Filed: 07/22/1983
• Issued: 09/09/1986
• Est. Priority Date: 11/24/1981
• Status: Expired due to Term

• Current Assignee: Andreas Weikl, Volkmar Merkel
• Original Assignee: Schneider Medintag AG
• Inventors: Weikl, Andreas, Merkel, Volkmar
• Primary Examiner(s): Thaler, Michael H.
• Application Number:
  US06/517,069
• Time in Patent Office: 1,145 Days
• Field of Search: 128/328, 128/344, 128/348.1, 604/101, 604/102, 604/53, 604/49-52, 604/54, 604/28, 604/265, 604/266, 604/269
• US Class Current: 604/509
• CPC Class Codes: A61B 2017/22054 with two balloons
• CPC Class Codes: A61B 2017/22084 stone- or thrombus-dissolving
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters

Abstract

For the provision of an apparatus to lessen or remove points of constriction in vessels of all types whereby ruptures and tears are to be avoided in the vessel walls and, during the treatment of stenosis in blood vessels, the danger of infarction is to be avoided, through use of a treatment catheter (1) that is equipped with two expandable balloons (4, 5) which seal off both sides of a point of constriction (6) in a vessel, whereby the degree of expansion of both balloons (4, 5) can be controlled externally, it is proposed that there be mounted in the wall of the treatment catheter (1) within the region confined by the balloons (4, 5) an inlet piece (A) for the supply of media capable of dissolving or crumbling into smaller particles the material (7) at the point of constriction and an outlet piece (B) for the removal of the material (7) dissolved or crumbled at the point of constriction, whereby these pieces are connected with an externally accessible conduit (10, 11) (FIG. 1).

Claims

1. A method of treating stenosis by eliminating or expanding the points of constriction which are customarily formed of a sponge-like calcified and fatty tissue in blood carrying vessels of the body through use of a flexible treatment catheter having separate support conduits formed by longitudinal partition walls and at whose end two balloons are situated, said method comprising the steps of sealing off the section of the blood vessel containing the stenosis with the two balloons, introducing a solvent of predetermined concentration and duration of effect to act upon the stenosis through a first support conduit in the catheter such that the tissue of the stenosis is dissolved, softened, or crumbled into smaller particles, and draining the particles from the sealed section of the blood vessel through a second separate support conduit.

2. The method defined in claim 1, and including maintaining the circulation of blood contained in the blood-carrying vessels to the downstream organs by a further separate support conduit in the catheter.

3. The method defined in claim 1, wherein the solvent, as determined by its type, concentration, and duration of effect, acts upon the stenosis only to soften the tissue to permit it to be removed as a whole by the treatment catheter when the treatment catheter is withdrawn from the vessel.

4. The method defined in claim 1, wherein the solvent, as determined by its type, concentration, and duration of effect, acts upon the stenosis to such an extent that the tissue of the stenosis is crumbled into smaller particles which are removed through the second separate draining support conduit of the treatment catheter.

5. The method defined in claim 1, wherein the solvents are selected from the group consisting of enzymes, acids and alkaline solutions.

6. The method defined in claim 5, wherein the acid is a nitrous acid.

7. The method defined in claim 5, wherein the alkaline solution is caustic soda.

8. The method defined in claim 1, characterized in that the duration of effect of the solvent on the stenosis is limited to a predetermined time interval by inhibitors.

9. The method defined in claim 1, and including a circulating rinse for the removal of the tissue at the point of constriction which has been dissolved, softened or crumbled into smaller particles.

10. The method defined in claim 9, characterized in that the double-balloon catheter is used for performing the circulating rinse process.