Imaging method and apparatus for obtaining spin-lattice relaxation time image utilizing nuclear magnetic resonance

• US 4,620,154 A
• Filed: 06/19/1984
• Issued: 10/28/1986
• Est. Priority Date: 07/20/1983
• Status: Expired due to Term

• Current Assignee: Kabushiki Kaisha Toshiba (Toshiba Corporation)
• Original Assignee: Kabushiki Kaisha Toshiba (Toshiba Corporation)
• Inventors: Inouye, Tamon
• Primary Examiner(s): Levy, Stewart J.
• Assistant Examiner(s): O'Shea, Kevin D.
• Application Number:
  US06/622,267
• Time in Patent Office: 861 Days
• Field of Search: 324/309, 324/312, 324/307
• US Class Current: 324/309
• CPC Class Codes: G01R 33/482 using a Cartesian trajectory
• CPC Class Codes: G01R 33/50 based on the determination of relaxation times , e.g. T1 measurement by IR sequences; T2 measurement by multiple-echo sequences

Abstract

A image is constructed from nuclear magnetic resonance image data which represent a characteristic of an object. Data are collected using the saturation-recovery method and the inversion-recovery method; a first and second image are produced from data from each method, respectively; and a third image is produced from the first and second image, depending only on a single relaxation time.

Claims

1. A method for producing an image of a slice of an object relating to a spin lattice relaxation time T₁ using a saturation-recovery method and an inversion-recovery method, comprising the steps of:

a. collecting a first data set from spin-echo signals using said saturation-recovery method;

b. collecting a second data set from spin-echo signals using said inversion-recovery method;

c. generating a first image from said first data set;

d. generating a second image from said second data set; and

e. generating a third image from a ratio of said first and second images.

2. The method for producing an image of a slice of an object as recited in claim 1, wherein said step of generating a third image includes dividing pixel data of said second image by corresponding pixel data of said first image.

3. An apparatus for generating an image of a designated slice of an object using a saturation recovery method and an inversion recovery method of nuclear magnetic resonance, comprising:

a. means for generating a uniform static magnetic field and applying said static magnetic field to said object;

b. means for generating a magnetic field gradient with said uniform static magnetic field thereby defining a slice of said object orthogonal to said field gradient for a particular resonance frequency;

c. means for generating first and second pulse sequences in accordance with said saturation-recovery method and said inversion-recovery method respectively, wherein each pulse sequence includes a selective excitation pulse (SEP) and a 180°

pulse;

d. means for generating an alternating magnetic field wherein said alternating magnetic field passes through said designated slice of said object and said alternating magnetic field is applied with said first and second pulse sequences generated by said first and second pulse sequence generating means;

e. means for detecting spin-echo signals from said object after a predetermined spin-echo interval from said 180°

pulse of said first and second pulse sequences;

f. means for reconstructing first and second images of said designated slice from said spin-echo signals corresponding to said saturation-recovery method and inversion-recovery method respectively; and

g. means for generating a third image from said first and second images, whereby said first, second and third image each include pixel data, and said third image pixel data represents a distribution of relaxation time T₁ on said designated slice, being a ratio of pixel data of said first image and corresponding pixel data of said second image.

4. A nuclear magnetic resonance image display device comprising:

a. means for generating a saturation-recovery pulse sequence and an inversion-recovery pulse sequence;

b. means for inducing nuclear magnetic resonance to atomic nuclei in a slice of an object;

c. means for detecting first NMR signals induced by said saturation-recovery pulse sequence and second NMR signals induced by said inversion-recovery pulse sequence;

d. means for reconstructing a saturation-recovery image and an inversion-recovery image from said first and second NMR signals, respectively, each image representing physical characteristics of the atomic nuclei in said slice of the object;

e. means for controlling said saturation-recovery and inversion-recovery pulse generating means, said inducing means, said detecting means and said reconstructing means;

f. means for generating a relaxation time T₁ image from said saturation-recovery image and said inversion-recovery image, said relaxation time T₁ image representing a distribution of relaxation time T₁ of said atomic nuclei in said slice of said object and each pixel data of said relaxation time T₁ image being obtained as a ratio between pixel data of said inversion-recovery image and corresponding pixel data of said saturation-recovery image;

g. means for storing said saturation-recovery image, inversion-recovery image, and relaxation time T₁ image; and

h. means for displaying at least one of said images stored in said storing means.

5. An image display device according to claim 4 wherein:

a. said saturation-recovery pulse sequence and said inversion-recovery pulse sequence include a selective excitation pulse (SEP) and a plurality of 180°

pulses; and

b. said detecting means includes means for detecting spin-echo signals as said first and second NMR signals, said spin-echo signals being sampled after a common spin-echo interval from each 180°

pulse.

6. An image display device according to claim 5 further comprising means for accumulating spin-echo signals, said accumulating means being coupled to said detecting means and said reconstructing means.

7. An image display device according to claim 4, wherein said inducing means further includes:

a. first means for generating a uniform static magnetic field through said object;

b. second means for generating a magnetic field gradient wherein said magnetic field gradient designates by nuclear magnetic resonance said slice of the object; and

c. third means for generating an alternating magnetic field in accordance with said saturation-recovery pulse sequence and said inversion-recovery pulse sequence.

8. An image display device according to claim 7 wherein said second generating means includes three coils, each generating respectively orthogonal magnetic field gradients.

9. An image display device according to claim 5, wherein said inducing means further includes:

a. first means for generating a uniform static magnetic field through said object;

b. second means for generating a magnetic field gradient wherein said magnetic field gradient designates by nuclear magnetic resonance said slice of the object; and

c. third means for generating an alternating magnetic field in accordance with said saturation-recovery pulse sequence and said inversion-recovery pulse sequence.

10. An image display device according to claim 9, wherein said second generating means includes three coils, each generating respectively orthogonal magnetic field gradients.