N-(phenyl) or N-(phenylcyclopropyl)-2,5-dihydro-2-oxo-4[(substituted phenyl)amino]-3-furancarboxamide derivatives
First Claim
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1. A Compound of the formula:
- ##STR4## Where R is selected from phenyl and phenyl mono or disubstituted with lower alkyl, nitro, halogenated methyl, halogen, lower alkoxy and combinations thereof;
Where R1 is selected from hydrogen and lower alkyl; and
Where R2 is selected from phenyl;
phenyl monosubstituted with lower alkyl, nitro, halogenated methyl, halogen and lower alkoxy; and
trans-phenylcyclopropyl in which the phenyl group may be substituted with lower alkyl and halogen.
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Abstract
Compounds which possess antiallergy activity have the formula: ##STR1## wherein R is selected from phenyl and phenyl mono or disubstituted with lower alkyl, nitro, halogenated methyl, halogen, lower alkoxy and combinations thereof;
wherein R1 is selected from hydrogen and lower alkyl; and
where R2 is selected from phenyl, phenyl monosubstituted with lower alkyl, nitro, halogenated methyl, halogen, and lower alkoxy, and trans-phenylcyclopropyl in which the phenyl group may be substituted with lower alkyl or halogen.
15 Citations
12 Claims
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1. A Compound of the formula:
- ##STR4## Where R is selected from phenyl and phenyl mono or disubstituted with lower alkyl, nitro, halogenated methyl, halogen, lower alkoxy and combinations thereof;
Where R1 is selected from hydrogen and lower alkyl; and Where R2 is selected from phenyl;
phenyl monosubstituted with lower alkyl, nitro, halogenated methyl, halogen and lower alkoxy; and
trans-phenylcyclopropyl in which the phenyl group may be substituted with lower alkyl and halogen. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
- ##STR4## Where R is selected from phenyl and phenyl mono or disubstituted with lower alkyl, nitro, halogenated methyl, halogen, lower alkoxy and combinations thereof;
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Current AssigneeFisons Limited (Sanofi )
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Original AssigneePennwalt Corporation (Arkema)
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InventorsGeorgiev, Vassil S., Mack, Robert A.
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Primary Examiner(s)Milestone, Norma S.
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Application NumberUS06/839,298Time in Patent Office257 DaysField of Search549/321US Class Current549/321CPC Class CodesA61P 37/08 Antiallergic agents antiast...C07D 307/68 Carbon atoms having three b...
