Intraoral ambient sensing device

• US 4,629,424 A
• Filed: 08/30/1984
• Issued: 12/16/1986
• Est. Priority Date: 08/30/1984
• Status: Expired due to Term

• Current Assignee: Integrated Ionics Incorporated
• Original Assignee: Integrated Ionics Incorporated
• Inventors: Lauks, Imants R., Yankell, Samuel L.
• Primary Examiner(s): Wilson, John J.
• Application Number:
  US06/645,940
• Time in Patent Office: 838 Days
• Field of Search: 433/6, 433/32, 433/167, 128/777, 128/776, 128/787, 455/100
• US Class Current: 433/6
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/228 of masticatory organs, e.g. detecting dental force
• CPC Class Codes: A61B 5/4205 Evaluating swallowing
• CPC Class Codes: A61B 5/4557 Evaluating bruxism
• CPC Class Codes: A61B 5/682 Mouth, e.g., oral cavity; tongue; Lips; Teeth

Abstract

A device is disclosed for intraoral ambient sensing. In this embodiment, the device comprises a removable oral (Hawley) appliance containing a number of chemically sensitive electrodes and a common reference electrode at the chemical sensing sites and a telemetry unit plus power pack for signal transmission. This device may also be used to monitor non-chemical parameters, notably pressure, temperature, and flow. In this embodiment, the removable oral (Hawley) appliance contains a number of sensors to monitor the parameter of interest. For example, a pressure sensor configured as an artificial uvula and mounted to the oral (Hawley) appliance emulates actual uvula pressure events. To monitor chewing events, a pressure sensor is mounted to the oral (Hawley) appliance in such a manner that it is optimally located at an open bite location of the mouth. In either embodiment, a telemetry unit mounted to the oral (Hawley) appliance transmits the intraoral ambient information as radio frequency signal bursts. A remotely located receiver circuit receives the radio signals which are broadcast and recovers the information encoded in them.

Claims

1. A dental assembly useful for the measurement of parametric changes throughout the oral cavity comprising:

a Hawley appliance;

a sensor assembly mounted on said Hawley appliance comprising one or more sensors having means for measuring parametric changes throughout the oral cavity and which provide an electrical output signal in response to said changes in one or more of the intraoral parameters;

a lead to each sensor;

means mounted on said Hawley appliance for transmitting said electrical output signal from the oral cavity using only a modulated radio frequency carrier; and

means for hermetically sealing said sensor assembly, said lead and said transmitting means.

2. The dental assembly of claim 1 wherein said transmitting means comprises:

a telemetry transmitter circuit mounted on said Hawley appliance for telemetry of signals from said intraoral sensor comprising;

signal conditioning means coupled to said sensor and responsive to its electrical output signal for producing signal amplification and filtering;

modulating means coupled to said signal conditioning means and responsive to its electrical output for encoding that signal output for telemetry transmission; and

transmitting means coupled to said modulating means and responsive thereto for generating an output signal representative of the signals from said

antenna transmitter device mounted on said Hawley appliance comprising an antenna element coupled to said telemetry circuit and responsive to the output signal of said circuit for broadcasting said signal to a remote location; and

a power pack assembly mounted on said Hawley appliance comprising a power pack element which provides electric energy to said telemetry transmission circuit and said sensor assembly.

3. The dental assembly of claim 1 wherein at least one sensor is a pH sensitive sputtered iridium oxide electrode for intraoral pH monitoring.

4. The dental assembly of claim 1 wherein at least one sensor is a pressure sensitive PV2 piezoelectric polymer sensor for intraoral chew event monitoring.

5. The dental assembly of claim 1 wherein at least one sensor is a pressure sensitive PV2 piezoelectric polymer sensor for intraoral swallow event monitoring.

6. The dental assembly of claim 1 wherein the telemetry transmitter circuit includes a switching means coupled to the modulating means and wherein the switching means is responsive to an output signal of said modulation means for synchronizing said signal with the input signal to the modulating means.

7. The dental assembly of claim 1 further comprising a remotely located receiver and demodulator circuit for receiving said broadcast signal and demodulating the same to obtain converted intraoral information.

8. The dental assembly of claim 1 wherein at least one sensor is a pressure sensitive PV2 piezoelectric polymer sensor for intraoral chew event monitoring that is located on an open bite location of the mouth where the maxillary and mandibula are not in contact when the mouth is closed and is held in place by a cantilever mounted on the Hawley appliance and terminating at the open bite location.

9. The dental assembly of claim 1 wherein at least one sensor is a pressure sensitive PV2 piezolelectric polymer sensor for intraoral swallow event monitoring wherein the sensor is located near the uvula and is held in place by a cantilever mounted on the Hawley appliance and terminating at the uvula location.

10. A method for modifying a Hawley appliance to mount a sensor and a telemetry unit for measurement of parametric changes throughout the oral cavity comprising the steps of:

attaching a sensor having means for measuring parametric changes throughout the oral cavity to the Hawley appliance so as to measure one or more of said parametric changes;

forming channels on the lingual side of said appliance for a radio telemetry unit, a power pack, an antenna, and wire interconnection placements;

interconnecting said sensors, telemetry unit, antenna, power pack by wires into a discrete package;

attaching telemetry unit, antenna, power pack and wire connections to the Hawley appliance; and

sealing all sensors, telemetry unit, antenna, power pack and wire conncetions against moisture migration.

11. The method of claim 10 comprising the additional steps of:

molding thicker acrylic on the lingual side of said appliance for interproximal sensor placement;

forming holes between the lingual side and interproximal side of said appliance to accommodate the sensors;

drilling holes between the lingual side and soft palate side of said appliance to permit fit of at least one reference sensor; and

positioning said sensors in said holes with sensors oriented toward intraoral activity to be monitored.

12. The method of claim 10 comprising the additional step of mounting one end of a cantilever onto the lingual side of the Hawley appliance with a sensor fixedly attached to the other end of said cantilever.

13. A method for remote monitoring of parametric changes throughout the oral cavity comprising the steps of

monitoring said parametric changes by one or more sensors having means for measuring parametric changes throughout the oral cavity and being mounted on a Hawley appliance within a patient'"'"'s mouth and capable of generating a signal proportional to the instantaneously measured parametric changes;

converting said monitored signals to proportional amplified and filtered signals;

modulating said signals for radio telemetry transmission;

broadcasting said modulated signal from the patient'"'"'s mouth upon a radio frequency carrier; and

receiving and demodulating said broadcast signal to obtain a signal whose waveform is similar to the electrical signals form the intraoral sensors.

14. A method for fabricating a thin film hybrid micro-circuit for telemetry of electric signals from intraoral sensing devices comprising the steps of:

depositing a chromium layer on the substrate;

depositing a gold layer on the substrate;

placing a first layer of negative-acting photoresist on the substrate;

placing a first mask containing a negative impression of the telemetry conducting line and bonding pad layout on the substrate;

exposing the photoresist layer through the mask to ultraviolet light;

removing the first mask;

developing and removing the unexposed portions of the photoresist;

etching the gold layer with a gold etchant;

removing the exposed photoresist, leaving bare the surface of the substrate except for the gold region covered by the conducting line and bonding pad

placing a second layer of positive-acting photoresist on the substrate;

placing a second mask containing a positive impression of the telemetry circuit conducting line layout on the substrate;

exposing the photoresist layer through the mask to ultraviolet light;

developing and removing the exposed portions of the photoresist;

baking the photoresist mask;

expoxying an integrated circuit with the telemetry circuit onto grounding pads epoxied to the substrate;

mounting at least one capacitor or resistor on the substrate;

connecting the integrated circuit to the substrate;

mounting at least one insulated wire onto the bonding pads for an external connection; and

covering the entire thin film hybrid micro-circuit with dental acrylic.

15. A dental assembly useful for the measurement of chemical or ionic species throughout the oral cavity comprising:

a Hawley appliance;

a sensor assembly having means for measuring parametric changes throughout the oral cavity and being mounted on said Hawley appliance comprising one or more electrochemical sensors and a reference electrode, said electrochemical sensors providing an electrical output signal in response to changes in one or more chemical or ionic properties;

a lead to each sensor and reference electrode;

means mounted on said Hawley appliance for transmitting said electrical output signal from the oral cavity using only a modulated radio frequency carrier; and

means for hermetically sealing said sensor assembly, said lead and said transmitting means.

16. The dental assembly of claim 15 wherein at least one sensor is a pH sensitive electrode for intraoral pH monitoring.