Reinforcing structure for cardiovascular graft

• US 4,629,458 A
• Filed: 02/26/1985
• Issued: 12/16/1986
• Est. Priority Date: 02/26/1985
• Status: Expired due to Fees

• Current Assignee: Corvita Corporation (Boston Scientific Corporation)
• Original Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Inventors: Pinchuk, Leonard
• Primary Examiner(s): Apley, Richard J.
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US06/705,782
• Time in Patent Office: 658 Days
• Field of Search: 3/1.4, 3/1.7, 273/DIG. 7, 623/1, 623/3, 623/66
• US Class Current: 623/1.47
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61L 27/48 with macromolecular fillers
• CPC Class Codes: C08L 89/06 derived from leather or skin , e.g. gelatin
• CPC Class Codes: Y10S 623/917 Collagen

Abstract

The reinforced tubular graft structure is particularly adapted for cardiovascular use and is made of collagenous tissue with a reinforcing fibrous structure surrounding the lumen. The fibrous structure comprises a coiled monofilament which can have a textured surface defined by randomly disposed strands of polymer on the outer surface of the monofilament. The coil can be embedded within the collagen or positioned about the collagen to form the graft structure.

Claims

1. A reinforced graft particularly adapted for cardiovascular use, said graft comprising:

a tubular structure having a central lumen and comprising collagenous tissue having a generally tubular shape and a single monofilament wound in a coil with spacing between the turns of the coil to permit the tubular structure to be bent without crimping, the turns having "radial compliance", i.e., the turns going from one pitch to another pitch during bending, and said monofilament having a smaller single monofilament painted thereon in an overlapping manner to form a textured mesh-type surface with random interstices into which tissue can grow, said coiled monofilament being situated externally of said lumen.

2. The graft of claim 1 wherein said coiled monofilament is centrally located within the collagenous tissue.

3. The graft of claim 1 wherein said coiled monofilament surrounds said collagenous tissue.

4. The graft of claim 1 wherein said coiled monofilament is situated about the lumen of said collagenous tissue.

5. The graft of claim 1 wherein said filament is a coiled monofilament.

6. The graft of claim 5 wherein turns said coiled monofilament have a pitch of approximately 60°

.

7. The graft of claim 3 wherein said filament is a coiled monofilament.

8. The graft of claim 1 wherein said coiled monofilament has a pitch of approximately 30°

to 70°

.

9. The graft of claim 1 wherein said fibrous structure is a coiled textured surface monofilament.

10. The graft of claim 1 wherein turns of said coiled monofilament have a pitch of approximately 60°

.

11. The graft of claim 1 wherein said coiled monofilament is made of polymeric material.

12. The graft of claim 11 wherein said polymeric material is polyethylene.

13. The graft of claim 11 wherein said polymeric material is polycarbonate.

14. The graft of claim 11 wherein said polymeric material is polyurethane.

15. The graft of claim 11 wherein said polymeric material is polyether sulfone.

16. The graft of claim 11 wherein said polymeric material is polypropylene.

17. The graft of claim 9 wherein said monofilament is coated with a filament of polymeric material to provide said textured surface.

18. The graft of claim 1 wherein said smaller monofilament is applied to the surface of the monofilament by the random intertwining or painting of a smaller monofilament of the polymeric material on said monofilament before coiling thereof.

19. The graft of claim 1 wherein said coiled monofilament is set by thermoforming.

20. The graft of claim 1 wherein said collagenous tissue embeds itself around the coiled monofilament by implantation of the structure within a living host.

22. The graft of claim 5 wherein said coiled monofilament is made of metal.

23. The graft of claim 22 wherein said metal is stainless steel.

24. The graft of claim 22 wherein said metal is nitinol.

25. The graft of claim 22 wherein said metal is elgiloy.

38. The graft of claim 1 wherein said monofilament is approximately 1/2 mm thick.

39. The graft of claim 1 wherein said smaller monofilament has a diameter of approximately 1 to 40 microns.

40. The graft of claim 1 having a wall thickness from said lumen to the outer surface of said graft of between 0.05 mm and 0.25 cm.

21. A reinforced graft particularly adapted for cardiovascular use, said graft comprising a tubular structure having a central lumen and comprising collagenous tissue, a single monofilament wound in a coil with spacing between the turns of the coil to permit the tubular structure to be bent within crimping, the turns having "radial compliance", i.e., the turns going from one pitch to another pitch during bending, and said monofilament having a smaller single monofilament painted thereon in an overlapping manner to form a textured mesh-type surface with random interstices into which tissue can grow, said coiled monofilament being situated externally of said lumen, and a tube of mesh screen disposed within said collagenous tissue and inwardly of said wound monofilament generally coaxial with the axis of the lumen of said tubular structure for further reinforcing the graft.

26. A reinforced graft particularly adapted for cardiovascular use comprising a tubular structure having a central lumen, said tubular structure being made of collagenous tissue and including in said tubular structure a single monofilament wound in a coil with spacing between the turns of the coil to permit the tubular structure to be bent without crimping, the turns having "radial compliance", i.e., the turns going from one pitch to another pitch during bending, and said monofilament having a smaller single monofilament painted thereon in an overlapping manner to form a textured mesh-type surface with random interstices into which tissue can grow, said coiled monofilament being situated within said collagenous tissue externally of said lumen.

27. The graft of claim 26 wherein said monofilament is coiled in turns having a pitch between approximately 30°

and approximately 70°

.

28. The graft of claim 26 wherein said monofilament is made of polymeric material.

29. The graft of claim 26 wherein said smaller monofilament is a filament of polymeric material.

30. The graft of claim 29 wherein said smaller monofilament is applied to the surface of said monofilament by random intertwining or painting of said smaller monofilament on the monofilament before coiling thereof.

31. The graft of claim 26 wherein said coiled monofilament is set by thermoforming.

41. The graft of claim 26 wherein said smaller monofilament has a diameter of approximately 1 to 40 microns.

32. A reinforced graft particularly adapted for cardiovascular use comprising a tubular structure having a central lumen, said tubular structure being made of collagenous tissue and including a single monofilament wound in a coil with spacing between the turns of the coil to permit the tubular structure to be bent without crimping, the turns having "radial compliance", i.e., the turns going from one pitch to another pitch during bending, and said monofilament having a smaller single monofilament painted thereon in an overlapping manner to form a textured mesh-type surface with random interstices into which tissue can grow, said coiled monofilament being situated externally of said collagenous tissue.

33. The graft of claim 32 wherein said monofilament is coiled in turns having a pitch between approximately 30°

and approximately 70°

.

34. The graft of claim 32 wherein said monofilament is made of polymeric material.

35. The graft of claim 32 wherein said monofilament is a filament of polymeric material.

36. The graft of claim 35 wherein said smaller monofilament is applied to the surface of said monofilament by random intertwining or painting of said smaller monofilament on the monofilament.

37. The graft of claim 32 wherein said coil is set by thermoforming.

42. The graft of claim 36 wherein said smaller monofilament has a diameter of approximately 1 to 40 microns.