Triphasic wave defibrillation

• US 4,637,397 A
• Filed: 05/30/1985
• Issued: 01/20/1987
• Est. Priority Date: 05/30/1985
• Status: Expired due to Fees

• Current Assignee: Case Western Reserve University
• Original Assignee: Case Western Reserve University
• Inventors: Jones, Ronald E., Jones, Janice L.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US06/739,133
• Time in Patent Office: 600 Days
• Field of Search: 128/419 D, 128/419 PG, 128/421
• US Class Current: 607/5
• CPC Class Codes: A61N 1/39 Heart defibrillators
• CPC Class Codes: A61N 1/3904 External heart defibrillators [EHD]
• CPC Class Codes: A61N 1/3906 characterised by the form of the shockwave

Abstract

Method and apparatus for stimulation of cells in arrhythmic myocardial tissues includes depolarizing the cells by application of a first electrical pulse or shock followed by a second electrical pulse having a polarity opposite to the first pulse. Finally, a third pulse having the same polarity as the first pulse is applied to the cells. Specific relationships between the magnitudes and durations of the pulses are advantageously employed for achieving the most desirable stimulation results.

Claims

1. A method for electrical defibrillation of fibrillating myocardial tissues comprising the steps of:

(a) defining a defibrillating pulse with a defibrillating polarity, a defibrillating voltage, and a defibrillating pulse width between three and fifteen milliseconds in duration;

(b) defining a conditioning pulse with a polarity opposite to the defibrillating polarity, a conditioning pulse voltage level between 20% and 200% of the defibrillating voltage, and a conditioning pulse width between three and fifty milliseconds in duration;

(c) defining a healing pulse with the opposite polarity as the defibrillating polarity, a healing pulse voltage level between 5% and 40% of the defibrillating voltage, and a healing pulse width between one and one-hundred milliseconds in duration; and

,

(d) applying the conditioning pulse, the defibrillating pulse, and the healing pulse in sequence to cells in said fabrillating myocardial tissues.

2. The method for defibrillation of claim 1 wherein the conditioning pulse, the defibrillating pulse, and the healing pulse voltages decrease over their respective pulse widths to final pulse voltages generally between 50% and 100% of their initial voltages.

3. The method for defibrillation of claim 1 wherein said steps of defining conditioning and healing pulses comprises said conditioning pulse voltage being 50% to 100% of said defibrillating pulse voltage and said healing pulse voltage being 5% to 20% of said defibrillating pulse voltage.

4. The method of defibrillation of claim wherein said steps of defining defibrillating, conditioning, and healing pulses comprises adjusting said defibrillating pulse width to be between five and ten milliseconds in duration, said conditioning pulse width to be between ten and forty milliseconds in duration, and said healing pulse to be between ten and fifteen milliseconds in duration.

5. A method for electrically stimulating cells in arrhythmic myocardial tissues, said method comprising the steps of:

(a) defining a conditioning pulse with a conditioning pulse time period, a conditioning pulse voltage, and a conditioning pulse polarity;

(b) defining a correcting pulse with a correcting pulse time period, and a correcting pulse voltage with a polarity opposite to that of said conditioning pulse voltage;

(c) defining a healing pulse with a healing pulse time period, and a healing pulse voltage with the same polarity as said conditioning pulse voltage; and

(d) applying the conditioning pulse, the correcting pulse, and the healing pulse in sequence to said cells in arrhythmic myocardial tissues.

6. The method for stimulating of claim 5 including the steps of establishing the correcting pulse voltage prior to the step of applying the conditioning pulse, and defining the conditioning pulse voltage at a level between 20% and 200% of the correcting pulse voltage and the healing pulse voltage at a level between 5% and 40% of the correcting pulse voltage.

7. The method for stimulating of claim 6 wherein the step of defining comprises having the conditioning pulse voltage be at a level between 50% and 100% of the correcting pulse voltage and the healing pulse voltage be at a level between 5% and 20% of the correcting pulse voltage.

8. The method for stimulating of claim 5 including the step of determining said conditioning and healing pulse voltages by using voltages which comprise percentage values of said predetermined correcting pulse voltage.

9. The method for stimulating of claim 8 further including the step of maintaining the conditioning pulse between three and fifty milliseconds, the correcting pulse between three and fifteen milliseconds, and the healing pulse between one and one hundred milliseconds.

10. The method for stimulating of claim 9 wherein said step of maintaining comprises setting the conditioning pulse to extend between ten and forty milliseconds, the correcting pulse to extend between five and ten milliseconds, and the healing pulse to extend between ten and fifteen milliseconds.

11. A method for stimulating of claim 5 including the steps of allowing each of said conditioning, correcting, and healing pulse voltages to decrease from their respective predetermined voltages over their respective time periods to final voltages.

12. The method for stimulating of claim 11 wherein said step of allowing comprises having said conditioning, correcting, and healing pulse final voltages equal to between 50% to 100% of their respective predetermined voltages.

13. A defibrillator device comprising:

means for generating a triphasic electrical wave including a conditioning pulse with a conditioning pulse polarity, a defibrillating pulse with a defibrillating pulse polarity opposite to the conditioning pulse polarity, and a healing pulse with a healing pulse polarity the same as the conditioning pulse polarity; and

,

means for selectively applying the triphasic wave to cells in arrhythmic myocardial tissues.

14. The defibrillator device of claim 13 including means for controlling the widths of said conditioning, defibrillating, and healing pulses, whereby the conditioning pulse may have a width between ten and forty milliseconds in duration, the defibrillating pulse may have a width between five and ten milliseconds in duration, and the healing pulse may have a width between one and one-hundred milliseconds in duration.

15. The defibrillator of claim 13 wherein said generating means includes means for providing said defibrillating pulse with a predetermined defibrillating pulse voltage, said conditioning pulse with a voltage between 20% and 200% of the defibrillating pulse voltage and said healing pulse with a voltage between 5% and 40% of the defibrillating pulse voltage.

16. The defibrillator of claim 15 wherein said generating means includes means for allowing the conditioning, defibrillation, and healing pulse voltages to decrease over their respective pulse widths to final voltages between 50% and 100% of their initial voltages.