Flow-through housing with blood gas sensors

• US 4,640,820 A
• Filed: 10/28/1983
• Issued: 02/03/1987
• Est. Priority Date: 10/28/1983
• Status: Expired due to Term

• Current Assignee: Terumo Cardiovascular Systems Corporation (Terumo Corporation)
• Original Assignee: Cardiovascular Decisions, LLC
• Inventors: Cooper, Robert P.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Gzybowski, Michael S.
• Application Number:
  US06/546,493
• Time in Patent Office: 1,194 Days
• Field of Search: 422/101, 422/81, 422/82, 422/48, 422/68, 436/178, 436/68, 210/433.2, 210/445, 210/451, 210/453, 210/321.1, 210/232, 210/335, 210/339
• US Class Current: 422/82.04
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/14557 specially adapted to extracorporeal circuits
• CPC Class Codes: G01N 21/05 Flow-through cuvettes G01N21/09 takes precedence; handling fluid samples G01N1/10
• CPC Class Codes: G01N 33/4925 measuring blood gas content, e.g. O2, CO2 , HCO3

Abstract

An apparatus for sensing characteristics of a substance, such as blood, including a membrane support having first and second recesses and first and second dissimilar membranes extending over the first and second recesses, respectively. The membrane support has a groove between the recesses, and edge portions of the membranes extend into the groove on the side thereof adjacent the first recess. A retaining bar is received within the groove, and the membranes are tightly held between the retaining bar and the wall of the groove to form a smooth, essentially continuous surface. The membrane support forms a portion of a flow passage so that blood can flow along the membranes. First and second sensors are mounted on the sides of the first and second membranes opposite the flow passage for sensing characteristics of the blood. The first and second sensors engage the first and second membranes, respectively, to tension the membranes.

Claims

1. A membrane support apparatus comprising:

a membrane support having first and second recesses;

first and second membranes extending over the first and second recesses, respectively, said first and second membranes being permeable to at least a component of a liquid;

means for mounting the first and second membranes on the membrane support with the membranes extending over the first and second recesses, respectively;

said mounting means including a groove in the membrane support between the recesses, edge portions of said membranes extending into said groove;

said mounting means including means for retaining the edge portions in said groove; and

said edge portions of said first membrane extending into said groove on a side thereof adjacent the first recess, and said second membrane extending over said retaining means on a side thereof facing outwardly of said groove and then extending into said groove to thereby form a smooth transition with said first membrane.

2. An apparatus as defined in claim 1 wherein said groove is rectangular in cross section for receiving the end portion of the first membrane, and said retaining means includes a retaining bar of generally rectangular cross-sectional configuration receivable in said groove.

3. An apparatus as defined in claim 1 wherein said first and second membranes are permeable to at least first and second components of the liquid, respectively, and said apparatus includes first and second sensors for sensing a characteristic of the first and second components, respectively, said first and second sensors engaging the first and second membranes respectively, and tensioning the membranes so engaged, said first sensor engaging the first membrane on a side thereof that faces the first recess and said second sensor engaging the second membrane on a side thereof that faces the second recess.

4. An apparatus as defined in claim 1 including a sensor support, a sensor carried by the sensor support for sensing a characteristic of said component of the liquid, and means for mounting the sensor support on the membrane support with said sensor being on a side of one of said membranes which faces the recess which said one membrane extends over.

5. An apparatus as defined in claim 1 including wall means defining a passage for flow of the liquid therethrough, said wall means including said membrane support, said membranes being dissimilar and said first and second recesses being separated from the passage by the first and second membranes, respectively.

6. An apparatus as defined in claim 5 wherein said second membrane is wrapped around at least 270 degrees of the retaining means.

7. An apparatus as defined in claim 5 wherein said retaining means includes a retaining bar and said edge portions of said membranes are tightly held between the retaining bar and a surface of the groove.

8. An apparatus as defined in claim 5 wherein a region of the edge portion of the second membrane extends beyond the edge portion of the first membrane within said groove and said region is adhered to a surface of the groove.

9. An apparatus as defined in claim 5 wherein said groove is rectangular in cross section, said retaining means includes a retaining bar of generally rectangular cross section a face of the retaining bar facing the passage, said membrane support has first and second generally flat surfaces between the groove and the first and second recesses, respectively, which are generally coplanar with said face of the bar, said edge portion of the second membrane extends at least partially around four faces of the rectangular retaining bar, a region of the edge portion of the second membrane extends beyond the edge portion of the first membrane within said groove and is adhered to a surface of the groove.

10. An apparatus as defined in claim 5 including means on the membrane support extending through at least one of said recesses for engaging and tensioning the membrane which extends over said at least one recess.

11. An apparatus as defined in claim 1 wherein the membrane support has first and second surfaces surrounding the first and second recesses, respectively, and longitudinal grooves extending along opposite longitudinal edges of the first and second surfaces, said mounting means includes adhesive in the longitudinal grooves adhering the membranes to the membrane support.

12. An apparatus as defined in claim 5 wherein one side of each of the membranes faces the passage and said apparatus includes a sensor support, first and second sensors carried by the sensor support for sensing first and second characteristics, respectively, of said component of the liquid, and means for mounting the sensor support on the membrane support with the first and second sensors being adjacent the first and second membranes on sides thereof opposite to said passage.

13. An apparatus as defined in claim 5 wherein said retaining means has a side facing said passage which is generally flat.

14. An apparatus as defined in claim 13 wherein said membrane support has first and second generally flat surfaces between the groove and the first and second recesses, respectively, which are generally coplanar with said side of the retaining means.

15. An apparatus as defined in claim 5 wherein said first and second membranes are permeable to at least first and second components of the liquid, respectively, and said apparatus includes first and second sensors for sensing a characteristic of the first and second components, respectively, said first and second sensors engaging the first and second membranes, respectively, on sides thereof opposite said passage and tensioning the membranes so engaged.

16. An apparatus as defined in claim 15 wherein said groove is rectangular in cross section, said retaining means includes a retaining bar of generally rectangular cross section with a face of the retaining bar facing the passage, said membrane support has first and second generally flat surfaces between the groove and the first and second recesses, respectively, which are generally coplanar with said face of the bar, and said edge portions of said membranes are tightly held between the retaining bar and a surface of the groove.

17. A flow through apparatus comprising:

wall means defining a passage for the flow of liquid therethrough, said wall means including a membrane support having a first recess;

a first membrane extending over the first recess, said membrane being exposable to a liquid on one side thereof and being permeable to at least a component of the liquid;

means for mounting the first membrane on the membrane support with the membrane extending over the recess;

said mounting means including a groove in said membrane support adjacent one end of the recess and a retaining bar; and

an edge portion of said membrane being wrapped at least part way around said retaining bar and extending over said retaining bar on a side thereof facing outwardly of said groove, said retaining bar and said edge portion being tightly received in said groove whereby the edge portion of the membrane is tightly held between the retaining bar and the wall of the groove.

18. An apparatus as defined in claim 17 including means on the membrane support extending through said first recess for engaging and tensioning the membrane.