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Hollow viscus tonometry

  • US 4,643,192 A
  • Filed: 02/27/1986
  • Issued: 02/17/1987
  • Est. Priority Date: 03/22/1982
  • Status: Expired due to Term
First Claim
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1. A method for detecting the onset of ischemia in a hollow internal organ which comprises providing a catheter having a catheter tube;

  • and a walled sampling chamber on the tube in communication with the interior of the tube;

    the wall of said walled sampling chamber comprising a material which is freely permeable to carbon dioxide gas in solution but poorly permeable to liquid fluid, introducing the catheter into the organ of interest so that the sampling chamber is disposed at a desired sampling site and leaving the sampling chamber disposed at the sampling site for a length of time sufficient to allow any carbon dioxide gas present at the sampling site to diffuse across the wall of the sampling chamber into aspirating liquid contained within the sampling chamber, withdrawing at least a portion of said aspirating liquid containing any diffused carbon dioxide gas via the catheter tube, analyzing the sample thus withdrawn for carbon dioxide, directly measuring the bicarbonate concentration of the article blood of the patient, determining of pH of said hollow internal organ at the sampling site on the carbon dioxide and bicarbonate measurements thus obtained, and determining whether ischemia is present on the basis of of pH determination.

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