Multiple compartment ampule for automatic hypodermic syringes

• US 4,643,721 A
• Filed: 11/15/1985
• Issued: 02/17/1987
• Est. Priority Date: 11/20/1984
• Status: Expired due to Fees

• Current Assignee: Poutrait-Morin
• Original Assignee: Poutrait-Morin
• Inventors: Brunet, Patrice
• Primary Examiner(s): Yasko, John D.
• Application Number:
  US06/798,439
• Time in Patent Office: 459 Days
• Field of Search: 604/191, 604/200-205, 604/87, 604/88, 604/90, 604/89
• US Class Current: 604/191
• CPC Class Codes: A61M 2005/1787 Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/287 by displacing occluding plugs
• CPC Class Codes: A61M 5/2066 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/286 upon internal pressure increase, e.g. pierced or burst A61M5/283 takes precedence
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing

Abstract

An ampule for an automatic hypodermic syringe comprises at least two axially aligned and hermetically separated compartments containing respective medicated substances. A nipple member is disposed at one end of the ampule. A needle holder is slidably mounted in said nipple member and supports a hollow needle. An intermediate partition normally hermetically separates the two compartments. The intermediate partition has a valve member adapted to open a path of flow through the intermediate partition to bring the second of the compartments into communication with the needle hollow after a first of the compartments is substantially emptied. Preferably, there are two intermediate partitions and three compartments.

Claims

1. An ampule for an automatic hypodermic syringe comprising at least two axially aligned and hermetically separated compartments adapted to contain respective medicated substances, a nipple member disposed at one end of the ampule, a needle holder mounted in said nipple member and supporting a hollow needle, said needle holder being displaceable between a standby position and an operative or injecting position, an intermediate partition normally hermetically separating said two compartments, said intermediate partition having a valve member, actuating means cooperable with said valve member after a first of said compartments is substantially emptied of its medicated substance to open a path of flow through said intermediate partition to bring the second of said compartments into communication with said hollow needle.

2. The ampule according to claim 1, wherein said needle holder also includes a support for a front end partition defining said actuating means for actuating said valve member when said first compartment is substantially emptied.

3. The ampule according to claim 2, wherein the front end partition which is adjacent said nipple member comprises a perforable central web adapted to be pierced by said hollow needle.

4. The ampule according to claim 3, wherein said actuating means and said valve member carried by said intermediate partition lie along the longitudinal axis of said ampule.

5. The ampule according to claim 1, wherein said intermediate piston comprises an axial recess with a pair of seats cooperable with complementary surfaces on the valve member to normally sealingly separate said compartments.

6. The ampule according to claim 5, wherein said valve seats are inclined in opposite directions so as to normally axially immobilize said valve member in said axial recess.

7. The ampule according to claim 5, wherein one of said seats is defined by a deformable annular lip.

8. The ampule according to claim 1, wherein there are two end partitions at the respective ends of said ampule and two said intermediate partitions disposed axially between said end partitions, to define three said compartments.

9. The ampule according to claim 8, wherein the valve member in the first mentioned intermediate partition is adapted to actuate the valve member in a second said intermediate partition after the second compartment between said intermediate partition is substantially emptied.

11. The ampule according to claim 1, wherein said needle holder is slidably mounted in said nipple member.

12. The ampule according to claim 11, wherein said nipple member is adapted to abut against an initially closed end of the ampule before the first compartment is empty.

10. An automatic hypodermic syringe comprising a drive mechanism and an ampule, said ampule comprising a least two axially aligned and hermetically separated compartments adapted to contain respectively medicated substances, a nipple member disposed at one end of said ampule, a needle holder slidably mounted in said nipple member and supporting a hollow needle, said needle holder being slidable between a standby position and an operative injecting position, an intermediate partition normally sealingly separating said two compartments, said intermediate partition having a valve member, actuating means cooperable with said valve member after a first of said compartments is substantially emptied of its medicated substance to open a path of flow through said intermediate partition to bring the second of said compartments into communication with said hollow needle.