Automatic analysis apparatus

• US 4,647,432 A
• Filed: 10/11/1983
• Issued: 03/03/1987
• Est. Priority Date: 11/30/1982
• Status: Expired due to Fees

• Current Assignee: Japan Tectron Instruments Corporation, Olympus Optical Company Ltd. (Olympus Corporation)
• Original Assignee: Japan Tectron Instruments Corporation Tokuyama Soda Kabushiki Kaisha
• Inventors: Wakatake, Koichi
• Primary Examiner(s): Richman, Barry S.
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US06/540,980
• Time in Patent Office: 1,239 Days
• Field of Search: 422/63-67, 422/100, 422/73, 356/246, 141/168, 141/169, 73/863.32
• US Class Current: 422/64
• CPC Class Codes: G01N 2035/00435 Refrigerated reagent storage
• CPC Class Codes: G01N 2035/00673 of reagents
• CPC Class Codes: G01N 2035/00752 bar codes
• CPC Class Codes: G01N 2035/041 lifting items out of a rack for access
• CPC Class Codes: G01N 2035/1025 Fluid level sensing
• CPC Class Codes: G01N 35/00663 of consumables
• CPC Class Codes: G01N 35/0095 introducing urgent samples with priority, e.g. Short Turn Around Time Samples [STATS]
• CPC Class Codes: G01N 35/025 having a carousel or turntable for reaction cells or cuvettes
• CPC Class Codes: G01N 35/1002 Reagent dispensers

Abstract

A novel automatic analysis apparatus in which a plurality of reaction tub according to the necessity, are held by a pair of turret tables disposed in predetermined spaces, and a reaction tube exchange means held between the tables automatically exchanges the reaction tubes held by one table for those of the other table at a predetermined position without stopping the rotation of the tables, and thereby achieves a charging operation, a measuring operation and a cleaning operation necessary for analysis of a specimen, such as blood, reagent or the like at a high speed with high precision and, in addition, facilitates measurement of an urgent specimen such as for operation.

Claims

1. An automatic analytical apparatus for optically measuring a specific colour produced by a reaction between a specimen and a reagent, the apparatus comprising:

at least two parallel rotatable turrets holding circularly arranged therein a plurality of reaction tubes containing specimens and reagents,

a reagent vessel holder disposed coaxially with one of said at least two turrets and holding circularly arranged therein a plurality of reagent vessels,

a first driving means for rotating the reagent vessel holder to bring a selected reagent vessel to a predetermined charging position,

charging means for charging reagent from a regent vessel at the charging position into an adjacent reaction tube,

reaction tube exchange means for simultaneously exchanging reaction tubes held at a predetermined position in a first one of said at least two turrets for reaction tubes held at a predetermined position in a second one of said at least two turrets, and

optical measuring means for optically measuring mixtures of specimen and reagent in the reaction tubes while the reaction tubes are held in the second one of said at least two turrets.

2. An apparatus according to claim 1, wherein the circular arrangement of reagent vessels is radially within the respective circular arrangement of reaction tubes.

3. An apparatus according to claim 1, wherein the reaction tube exchange means is positioned between said at least two reaction tube holding turrets and includes an arm with means at each end thereof for gripping and lifting a reaction tube from each of said at least two turrets, and means for rotating the arm through 180°

.

4. An apparatus according to claim 1, comprising a plurality of pipettes in a turret pipette holder and means connected to said turret pipette holder to intermittently rotate and move the pipettes from a specimen sucking position to a pipette cleaning position through a specimen charging position at which a specimen is charged into a respective reaction tube held in the first one of said at least two turrets.

5. An apparatus according to claim 4, wherein there are two specimen sucking positions corresponding to routine and emergency measurements respectively, and each of said pipettes is arranged to suck a specimen at a selected one of these positions.

6. An apparatus according to claim 4, further comprising a second driving means for rotating the reaction tubes held in the second one of said at least two turrets through at least 360°

plus one pitch, in synchronism with one stepwise rotation of the reaction tube exchange means.

7. An apparatus according to claim 1, wherein each reagent vessel has a projecting wall portion formed at one part of the vessel in communication with the interior of the vessel.

8. An apparatus according to claim 7, wherein the reagent vessel holder has, adjacent to its center, detecting means which is positioned and arranged to move up and down the projecting wall portion of a respective reagent vessel so as to sense the level of a liquid in the vessel.

9. An apparatus according to claim 8, wherein the projecting wall portion carries indicia relevant to the reagent in the respective vessel.

10. An apparatus according to claim 9, wherein the reagent vessel holder has means for reading said indicia, and said driving means for rotating the reagent vessel holder is responsive to said reading means.