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Implantable biological tissue and process for preparation thereof

  • US 4,648,881 A
  • Filed: 11/29/1982
  • Issued: 03/10/1987
  • Est. Priority Date: 03/23/1982
  • Status: Expired due to Term
First Claim
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1. A process for treating biological tissue prior to implantation which comprises the steps of:

  • a. contacting said tissue with a phosphate-deficient solution, said solution having a level of phosphate decreased to an amount effective in reducing calcification of said tissue after implantation, said solution further being non-destructive or non-destabilizing to said tissue; and

    b. maintaining the tissue in contact with such a phosphate-deficient solution during fixation, sterilization, and post-fixation storage of said tissue.

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