Recombinant bacterial plasmids containing the coding sequences of insulin genes
First Claim
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1. A recombinant plasmid replicable in procaryotic host containing within its nucleotide sequence a subsequence having the structure of the reverse transcript of an mRNA of a vertebrate, which mRNA encodes insulin.
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Abstract
A recombinant procaryotic microorganism containing the gene coding for insulin.
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7 Claims
- 1. A recombinant plasmid replicable in procaryotic host containing within its nucleotide sequence a subsequence having the structure of the reverse transcript of an mRNA of a vertebrate, which mRNA encodes insulin.
- 2. A recombinant procaryotic microorganism modified to contain a nucleotide sequence having the structure of the reverse transcript of an mRNA of a vertebrate, which mRNA encodes insulin.
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3. The bacterium Escherichia coli which has been modified to contain a nucleotide sequence having the structure of and transcribed from the rat gene for insulin.
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