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Self-calibrating single-use sensing device for clinical chemistry and method of use

  • US 4,654,127 A
  • Filed: 11/27/1985
  • Issued: 03/31/1987
  • Est. Priority Date: 04/11/1984
  • Status: Expired due to Term
First Claim
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1. A disposable single use sensing device for use with a clinical chemistry analyzer which determines a concentration of a selected chemical species in a sample fluid based upon sensor signals received at a receptacle, the sensing device comprising:

  • a carrier;

    a calibrant chamber for containing a calibrant fluid;

    a sample chamber for containing the sample fluid;

    a capillary passage supported by the carrier and having an inlet and having an outlet which is open to ambient air;

    first rupturable seal means for sealing an end of the calibrant chamber;

    second rupturable seal means for sealing an end of the sample chamber;

    means for defining a start position in which neither the calibrant chamber nor the sample chamber is connected to the inlet, a calibrant test position in which the calibrant chamber is connected to the inlet, and a sample test position in which the sample chamber is connected to the inlet;

    means for rupturing the first seal means to permit the calibrant chamber to be connected to the inlet and rupturing the second seal means to permit the sample chamber to be connected to the inlet;

    mounting means for mounting the calibrant and sample chambers to permit sequential relative movement of the chambers with respect to the inlet of the capillary passage from the start position to one of the test positions to draw the fluid from one of the chambers into the capillary passage and then to the other of the test positions to draw the fluid from the other chamber into the capillary passage, the fluid being drawn at least in part by capillary action; and

    sensing means for sensing concentration of the chemical species, the sensing means being positioned in communication with the capillary passage to provide sensor signals which are a function of sensed concentrations of the chemical species in the calibrant fluid and in the sample fluid.

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