Peritoneal artificial lung

• US 4,661,092 A
• Filed: 12/09/1983
• Issued: 04/28/1987
• Est. Priority Date: 12/09/1983
• Status: Expired due to Fees

• Current Assignee: Jack W. Moncrief, Robert P. Popovich
• Original Assignee: Jack W. Moncrief, Robert P. Popovich
• Inventors: Moncrief, Jack W., Popovich, Robert P.
• Primary Examiner(s): Yasko, John D.
• Application Number:
  US06/559,783
• Time in Patent Office: 1,236 Days
• Field of Search: 604/23-33, 128/4, 128/6, 128/914, 424/350-353, 422/44-45, 210/927
• US Class Current: 604/26
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/1698 Blood oxygenators with or without heat-exchangers intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 1/32 Oxygenators without membranes
• CPC Class Codes: A61M 2202/0476 Oxygenated solutions

Abstract

A process for the treatment of hypoxia is provided. The process involves the infusion of highly oxygenated perfluoro-chemicals into the peritoneal cavity of a patient, for oxygen transport into the body and carbon dioxide transport out of the body. The oxygenated perfluorocarbons are subsequently removed from the peritoneal cavity. The infusion and removal can be on a continuous or intermittent basis.

Claims

1. A process for the treatment of hypoxia, comprising the steps of:

infusing oxygenated perfluorochemicals into the peritoneal cavity of a patient, for oxygen transport into the body; and

removing the oxygenated perfluorochemicals from the peritoneal cavity.

2. A process for the treatment of hypoxia, comprising the steps of:

providing a source of oxygenated perfluorochemicals;

providing fluid inflow access to the peritoneal cavity of a patient;

providing for fluid outflow discharge from the peritoneal cavity of the patient; and

establishing a continuous flow of oxygenated perfluorochemicals through the peritoneal cavity of the patient, for oxygen transport into the patient'"'"'s body.

3. A process for the treatment of hypoxia, comprising the steps of:

infusing an oxygen-carring substance into the peritoneal cavity of a patient, for oxygen transport into the body; and

removing the substance from the peritoneal cavity.

4. The process of claim 3 wherein said oxygen-carrying substance has added thereto a vasoactive drug prior to infusion into the peritoneal cavity.

5. A process for the treatment of hypoxia, comprising the steps of:

providing a source of an oxygen-carring fluid substance;

providing fluid inflow access to the peritoneal cavity of a patient;

providing for fluid outflow discharge from the peritoneal cavity of the patient; and

establishing a continuous flow of the oxygen-carrying fluid substance through the peritoneal cavity of the patient, for oxygen transport into the patient'"'"'s body.

6. A process for the treatment of hypoxia, comprising the steps of:

providing an oxygen-carrying substance;

providing fluid access to the peritoneal cavity of a patient; and

intermittently infusing into and draining from the peritoneal cavity the oxygen-carrying substance, for providing oxygen transport into the body and carbon dioxide removal from the body.

7. A process for the treatment of hypoxia, which comprises the step of establishing a continuous flow of an oxygen-carrying substance through the peritoneal cavity of a patient, for oxygen transport into the patient'"'"'s body, using apparatus comprising:

a first indwelling adapted to be surgically implanted in the peritoneal cavity of a patient to provide a fluid inflow access port;

a second indwelling catheter adapted to be surgically implanted in the peritoneal cavity of the patient to provide a fluid outflow port;

a source of oxygenated perfluorochemicals;

means for establishing circulation of oxygenated perfluorochemicals through the patient'"'"'s peritoneal cavity from said source via said catheters.