Non-surgical method for suppression of tumor growth

• US 4,671,254 A
• Filed: 03/01/1985
• Issued: 06/09/1987
• Est. Priority Date: 03/01/1985
• Status: Expired due to Term

• Current Assignee: Memorial Hospital For Cancer and Allied Diseases A Not-For-Profit Corporation
• Original Assignee: Memorial Hospital For Cancer & Allied Diseases Incorporated
• Inventors: Fair, William R.
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): Jaworski, Francis J.
• Application Number:
  US06/708,438
• Time in Patent Office: 830 Days
• Field of Search: 128/24 A, 128/24 R, 128/303 R, 128/303.1, 128/328, 128/804, 128/1 R
• US Class Current: 601/3
• CPC Class Codes: A61B 18/20 using laser
• CPC Class Codes: A61B 2017/22091 Explosive
• CPC Class Codes: A61N 5/02 using microwaves
• CPC Class Codes: A61N 7/00 Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092

Abstract

This invention relates to a method for the non-surgical treatment of tumors. The method of this invention involves the use of shock waves to effect subcellular destruction of tumor cells, to alter their tumorigenic potential, and to suppress tumor growth.

Claims

1. A method for treating a tumor comprising tumor cells in vivo in the body of an animal, said method comprising the steps of exposing said tumor cells in vivo to a shock wave.

2. The method according to claim 1, wherein the body is immersed in a medium which is capable of propagating the shock wave.

3. The method according to claim 2, wherein the medium is liquid.

4. The method according to claim 1, wherein the tumor is located by a procedure selected from the group consisting of visual inspection, fluoroscopy, ultrasound, nuclear magnetic resonance, and CT scanning.

5. The method according to claim 1, wherein the shock wave is generated by a means selected from the group consisting of spark discharge means, laser, and means for producing a chemical explosion.

6. The method according to claim 1, wherein the shock wave is focused to coincide with the location of the tumor.

7. The method according to claim 1, wherein the animal is a human.

8. The method according to claim 1, wherein more than one tumor in the body is concurrently treated.

9. The method according to claim 1, wherein the frequency of the shock wave is within a range from about 100,000 hz to about 100 mhz.

10. The method according to claim 1, wherein the frequency of the shock wave is within a range from about 500,000 hz to about 50 mhz.

11. The method according to claim 1, further comprising exposing the tumor to a series of shock waves.

12. The method according to claim 11, wherein the number of shock waves administered per treatment is from about 500 to about 6000.

13. The method according to claim 11, wherein the number of shock waves administered per treatment is from about 800 to about 3000.

14. The method according to claim 1, further comprising the steps of protecting tissue surrounding the tumor by placing on said tissue, material capable of deflecting said shock waves.

15. A method according to claim 14, wherein said material is styrofoam.

16. The method according to claim 1, in combination with a cancer treatment selected from the group consisting of chemotherapy, immunotherapy, and radiation therapy.