Method of and apparatus for reconstructing shape of interested part of object through irradiation with X-rays

• US 4,672,651 A
• Filed: 02/28/1986
• Issued: 06/09/1987
• Est. Priority Date: 03/28/1985
• Status: Expired due to Fees

• Current Assignee: Hitachi Medical Corporation (Hitachi, Ltd.)
• Original Assignee: Hitachi Medical Corporation (Hitachi, Ltd.)
• Inventors: Matsuo, Hiroshi, Iwata, Akira, Suzumura, Nobuo, Horiba, Isao
• Primary Examiner(s): Church, Craig E.
• Assistant Examiner(s): Porta, David P.
• Application Number:
  US06/834,814
• Time in Patent Office: 466 Days
• Field of Search: 364/414, 378/62, 378/8, 378/9, 378/901, 378/14, 378/22-57, 378/210, 358/111
• US Class Current: 378/62
• CPC Class Codes: A61B 6/481 involving the use of contrast agents
• CPC Class Codes: A61B 6/504 for diagnosis of blood vessels, e.g. by angiography
• CPC Class Codes: G01N 23/043 using fluoroscopic examination, with visual observation or video transmission of fluoroscopic images
• CPC Class Codes: G06T 11/006 Inverse problem, transformation from projection-space into object-space, e.g. transform methods, back-projection, algebraic methods
• CPC Class Codes: G06T 2211/412 Dynamic
• CPC Class Codes: H04N 5/3205 using subtraction imaging techniques
• CPC Class Codes: H05G 1/60 Circuit arrangements for obtaining a series of X-ray photographs or for X-ray cinematography
• CPC Class Codes: Y10S 378/901 Computer tomography program or processor

Abstract

An object is irradiated with respective cone-beam like X-rays from first and second directions. For each of the first and second directions are produced mask and live images as respective projection images of the object before and after a contrast medium reaches an interested part of the object. Then, subtraction of the mask image from the live image is made in conjunction with each of the first and second directions. The resulting subtraction image assumes a projection image of the distribution of the contrast medium in the interested part taken in the corresponding direction. The respective projection widths of such projection images of the contrast medium distribution are determined to generate an ellipse defined by the projection widths. The shape of this ellipse is corrected in accordance with individual data values in the projection images of the contrast medium, thereby providing a corrected shape accurately resembling the actual shape of the interested part of the object. The corrected shape of the interested part is displayed.

Claims

1. A method of reconstructing the shape of an interested part of an object through irradiation thereof with X-rays and on the basis of data representative of a distribution of absorbances of the X-rays in the object and displaying the reconstructed shape, comprising:

a first step of injecting a contrast medium into the object;

a second step of irradiating the object with first cone-beam like X-rays from a first direction in a first period before the contrast medium reaches the interested part of the object, detecting the X-rays transmitted through the object and producing a first group of data values indicative of absorbances through the object for respective X-ray beams in said first cone-beam like X-rays in said first direction;

a third step of irradiating the object with second cone-beam like X-rays from said first direction in a second period after the contrast medium reaches the interested part of the object, detecting the X-rays transmitted through the object and producing a second group of data values indicative of absorbances through the object for respective X-ray beams in said second cone-beam like X-rays in said first direction;

a fourth step of irradiating the object with third cone-beam like X-rays from a second direction transverse from said first direction in a third period before the contrast medium reaches the interested part of the object, detecting the X-rays transmitted through the object and producing a third group of data values indicative of absorbances through the object for respective X-ray beams in said third cone-beam like X-rays in said second direction;

a fifth step of irradiating the object with fourth cone-beam like X-rays from said second direction in a fourth period after the contrast medium reaches the interested part of the object, detecting the X-rays transmitted through the object and producing a fourth group of data values indicative of absorbances through the object for respective X-ray beams in said fourth cone-beam like X-rays in said second direction;

a sixth step of subtracting said first data group from said second data group to produce a first projection data image of a distribution of the contrast medium in said interested part in said first direction;

a seventh step of subtracting said third data group from said fourth data group to produce a second projection data image of a distribution of the contrast medium in said interested part in said second direction;

an eight step of processing said first and second projection data images to reconstruct a shape of said interested part, said eight step including determining respective widths of projection of said first and second projection data images to establish an ellipse defined by said projection widths as a preliminary shape of said interested part and correcting the shape of said ellipse in accordance with individual data values of said first and second projection data images to provide a corrected shape of said interested part; and

a ninth step of displaying the corrected shape of said interested part.

2. A method according to claim 1, wherein when said interested part of said object repeats a motion at a substantially constant period, said method further comprises a tenth step of deriving from said object a monitor signal which resembles the motion of said interested part, said first to fourth data groups at said second to fifth steps being taken at the substantially indentical time phases of said monitor signal.

3. A method according to claim 1, wherein the correction at said eight step includes:

a first phase of detecting the maximum value of said first projection data image and dividing this maximum value by said projection width of said second projection data image to determine an X-ray absorption coefficient of the contrast medium for said first direction;

a second phase of dividing the individual data values of said first projection data image by the contrast medium absorption coefficient for said first direction to provide thickness values of said interested part in said first direction;

a third phase of detecting the maximum value of said second projection data image and dividing this maximum value by said projection width of said first projection data image to determine an X-ray absorption coefficient of the contrast medium for said second direction;

a fourth phase of dividing the individual data values of said second projection data image by the contrast medium absorption coefficient for said second direction to provide thickness values of said interested part in said second direction;

a fifth phase of taking differences between thickness values of said ellipse in one of said first and second directions and the thickness values of said interested part in said one direction to correct the individual thickness values of said ellipse in said one direction in accordance with the results of the differences, thereby producing a corrected shape; and

a sixth phase of taking differences between thickness values of said corrected shape in the other of said first and second directions and the thickness values of said interested part in said other direction to judge whether or not the result of the differences satisfies a predetermined relation,

wherein when said predetermined relation is satisfied at said sixth phase, said corrected shape produced at said fifth phase is deemed as a final corrected shape of said interested part, and wherein when said predetermined relation is not satisfied at said sixth phase, said fifth and sixth phases are repeated, until said predetermined relation is satisfied, so that the fifth phase is carried out again in conjunction with one of said first and second directions other than the direction taken at the preceding fifth phase while taking the corrected shape produced at that preceding fifth phase as a shape to be newly corrected and the sixth phase is carried out again in conjunction with one of said first and second directions other than the direction taken at the preceding sixth phase and for a corrected shape produced at the again carried-out fifth phase.

4. A method according to claim 1, wherein the injection of the contrast medium at said first step includes first and second injections of the contrast medium, said second and third steps being both carried out in conjunction with the first contrast medium injection, and thereafter said fourth and fifth steps being both carried out in conjunction with the second contrast medium injection.

5. A method according to claim 1, wherein the contrast medium is injected once at said first step, said second and fourth steps being successively carried out before said contrast medium reaches said interested part of said object, and thereafter said third and fifth steps being successively carried out after said contrast medium reaches said interested part of said object.

6. An apparatus for reconstructing the shape of an interested part of an object through irradiation thereof with X-rays and on the basis of data representative of a distribution of absorbances of the X-rays in the object and displaying the reconstructed shape, comprising:

a set of X-ray generating means and X-ray detecting means disposed opposite to each other with the object interposed therebetween so that said X-ray generating means generates cone-beam like X-rays in a predetermined period from each of first and second transverse directions and said X-ray detecting means detects an intensity of the X-rays transmitted through said object;

injector means for injecting a contrast medium into said object;

control circuit means for controlling said X-ray generating means and said injector means, said control circuit means supplying to said injector means a control signal indicative of the injection of the contrast medium into said object, said control circuit means also supplying, to said X-ray generating means, control signals which cause said X-ray generating means to generate first and second cone-beam like X-rays in said first direction in first and second periods before and after the contrast medium reaches the interested part of said object respectively as well as control signals which cause said X-ray generating means to generate third and fourth cone-beam like X-rays in said second direction in third and fourth periods before and after the contrast medium reaches the interested part of said object respectively;

transformation means connected with an output of said X-ray detecting means for transforming output signals of said X-ray detecting means representative of respective intensities of said first to fourth cone beam like X-rays transmitted through said object into absorbance values to produce first to fourth data groups for said first to fourth cone beam like X-rays, each of said first to fourth data groups including data values indicative of absorbances through said object for respective X-ray beams in the corresponding cone-beam like X-rays;

an operation processing section connected with an output of said transformation means, said operation processing means including first operation means for subtracting said first data group from said second data group to produce a first projection data image of a distribution of the contrast medium in said interested part in said first direction while subtracting said third data group from said fourth data group to produce a second projection data image of a distribution of the contrast medium in said interested part in said second direction, second operation means for determining respective widths of projection of said first and second projection data images to generate an ellipse defined by said projection widths as a preliminary shape of said interested part, and third operation means for comparing the shape of said ellipse with individual data values of said first and second projection data images to correct the shape of said ellipse in accordance with those data values into a corrected shape; and

display means for displaying the corrected shape produced by said third operation means.

7. An apparatus according to claim 6, wherein said set of X-ray generating means and X-ray detecting means include a pair of X-ray source and X-ray detector arranged opposite to each other on a supporting member which is rotatable to place said pair of X-ray source and X-ray detector into a first fixed position at which they oppose to each other in said first direction and a second fixed position at which they oppose to each other in said second direction, said X-ray source generating said first and second cone-beam like X-rays at said first fixed position and said third and fourth cone-beam like X-rays at said second fixed position, and a time sequence of said first to fourth periods being established in this order.

8. An apparatus according to claim 6, wherein said set of X-ray generating means and X-ray detecting means include a first pair of X-ray source and X-ray detector arranged on a supporting member opposite to each other in said first direction and a second pair of X-ray source and X-ray detector arranged on said supporting member opposite to each other in said second direction, the X-ray source in said first pair generating said first and second cone-beam like X-rays while the X-ray source in said second pair generating said third and fourth cone-beam like X-rays, and a time sequence of said first to fourth periods being established in the order of said first, third, second and fourth periods.