Method and apparatus for visual-evoked responses

• US 4,676,611 A
• Filed: 11/14/1984
• Issued: 06/30/1987
• Est. Priority Date: 11/14/1984
• Status: Expired due to Fees

• Current Assignee: New York University
• Original Assignee: New York University
• Inventors: Nelson, Jeremiah, Kupersmith, Mark J.
• Primary Examiner(s): Bovernick, Rodney B.
• Application Number:
  US06/671,474
• Time in Patent Office: 958 Days
• Field of Search: 351/205, 351/225, 351/238, 351/211, 351/243
• US Class Current: 351/205
• CPC Class Codes: A61B 5/377 using evoked responses
• CPC Class Codes: A61B 5/378 Visual stimuli
• CPC Class Codes: F02B 2075/027 four

Abstract

In an apparatus for assessing visually-evoked response, wherein stimulus means are provided to present a variable visual pattern to an observer and analyzing means are provided to analyze scalp potentials of the observer responsive to said pattern; the improvement wherein the stimulus means comprise means for temporal modulation of the pattern at a determined rate and simultaneously sweeping another visual parameter, in a determined period, in a range which crosses an observer'"'"'s visual threshold for said other parameter, said analyzing means comprising means for synchronously demodulating said scalp potentials employing said determined rate of the temporal modulation as a reference, at a plurality of different phases with respect to said reference, for producing a display of the scalp potentials demodulated with different phase reference.

Claims

1. In an apparatus for assessing visually-evoked response, wherein stimulus means are provided to present a variable visual pattern to an observer and analyzing means are provided to analyze scalp potentials of the observer responsive to said pattern;

the improvement wherein the stimulus means comprise means for temporal modulation of said pattern at a determined rate and simultaneously sweeping another visual parameter, in a determined period, in a range which crosses an observer'"'"'s visual threshold for said other parameter, said analyzing means comprising means for synchronously demodulating said scalp potentials employing said determined rate of the temporal modulation as a reference, at a plurality of different phases with respect to said reference, for producing a display of the scalp potentials demodulated with different phase references.

2. The apparatus for assessing visually-evoked response in accordance with claim 1, wherein said analyzing means further comprises means for inverting the output of said means for synchronously demodulating, and means responsive to the inverted and uninverted output of said means for synchronously demodulating for producing said display.

3. The apparatus of claim 1 wherein said visual parameter is contrast, and said means for sweeping said other visual parameter comprises sweeping said contrast from the level of indistinguishable to a level of distinguishable contrast.

4. The apparatus for assessing visually-evoked response of claim 1 wherein said other parameter is acuity, and said means for sweeping said other visual parameter comprises means for sweeping the spatial frequency of said pattern, in cycles of said pattern per degree of visual arc of vision of said observer, from a level at which said pattern is readily visible to a level at which said pattern is not visible to said observer.

5. The apparatus for assessing visually-evoked response of claim 1 wherein said means for synchronously demodulating comprises a plurality of phase-sensitive detectors.

6. In a method for assessing visually-evoked response wherein a variable visual pattern is presented to an observer and the scalp potentials of the observer responding to the stimulus of the variable visual patterns are analyzed;

the improvement comprising sweeping a visual parameter of said variable visual pattern, in a predetermined period, in a range which crosses an observer'"'"'s visual threshold for said parameter, temporally modulating said pattern at a determined rate during said sweeping, synchronously demodulating said scalp potentials employing said determined rate of the temporal modulation as a reference, at a plurality of different phases with respect to said reference, and producing a display from said demodulated potentials.

7. The method of claim 6 wherein said step of sweeping comprises sweeping contrast of said visual pattern.

8. The method of claim 6 wherein said step of sweeping said visual parameter comprises sweeping the spatial frequency of said pattern, in cycles of the pattern per degree of visual arc of the observer.

9. The method of claim 7 or 8 further comprising varying the selected orientation of said pattern.

10. In a method for assessing visually-evoked response by varying a stimulus of a visual pattern presented to an observer and analyzing scalp potentials of said observer in response to said pattern;

the improvement comprising sweeping a visual parameter of said pattern a plurality of times, each in a determined period, in a range which crosses an observer'"'"'s visual threshold for said parameter, at least one of said sweeps starting below said visual threshold and at least another of said sweeps starting above said visual threshold, temporally modulating said pattern at a determined rate during said sweeping, synchronously demodulating said scalp potentials employing said determined rate of the temporal modulation as a reference, and producing a display from said demodulated scalp potentials, whereby the differences of thresholds of upwardly and downwardly swept visual parameter is a measure of adaptation of said observer.

11. The method of claim 10 wherein said step of sweeping comprises sweeping the contrast of said pattern.

12. The method of claim 10 wherein said step of sweeping comprises sweeping the frequency of said pattern in cycles per degree of visual arc of said observer.

13. In a method for assessing visually-evoked response wherein a variable visual pattern is presented to an observer and the scalp potentials of the observer responding to the stimulus of the variable visual patterns are analyzed;

the process of selecting a low spatial frequency for the pattern of substantially 1 cycle/degree and sweeping a reversal rate thereof over an entire range of 1 to 50 reversal per second;

observing a response peak at substantially 43 reversals per second;

executing further testing with said reversal rate held constant at the value producing the observed response peak, with said spatial frequency remaining fixed at 1 cycle per degree;

contrast threshold determinations made by sweeping contrast of said pattern constituting a non-invasive test which isolates the performance and integrity of the Y-type retinocortical pathways, whereby the oblique effect is abolished.