Urobilinogen control

• US 4,677,075 A
• Filed: 05/05/1986
• Issued: 06/30/1987
• Est. Priority Date: 05/05/1986
• Status: Expired due to Term

• Current Assignee: Louderback, Allan L., Paul R. Szatkowski
• Original Assignee: Louderback, Allan L., Paul R. Szatkowski
• Inventors: Szatkowski, Paul R., Louderback, Allan L.
• Primary Examiner(s): Kyle, Deborah L.
• Assistant Examiner(s): Wallen, T. J.
• Application Number:
  US06/859,339
• Time in Patent Office: 421 Days
• Field of Search: 436/8-18, 436/44, 436/63, 436/96-99, 422/56, 514/55, 514/167, 514/330
• US Class Current: 436/12
• CPC Class Codes: G01N 33/72 involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
• CPC Class Codes: Y10T 436/10 Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
• CPC Class Codes: Y10T 436/103332 Bilirubin or uric acid standard or control
• CPC Class Codes: Y10T 436/108331 Preservative, buffer, anticoagulant or diluent

Abstract

A stable control solution is provided for the determination of urobilinogen. The control solution comprises an aqueous solution of about 3-12% ethylene glycol, about 0.1% protein and preferably about 40-400 mg/dl urobilinogen, said composition buffered to pH about 8.0-9.0 and retained in a hermetically sealed container under a blanket of inert gas.

Claims

1. A stable control solution for the determination of urobilinogen comprising an aqueous solution of from about 3% to about 12% ethylene glycol, about 0.1% protein, and an amount of urobilinogen sufficient to develop upon dilution in use an activity of from about 0.1 to about 20 mg/dl urobilinogen, said composition being buffered to a pH of from about 8.0 to about 9.0 and retained in a hermetically sealed container under a blanket of inert gas.

2. The control solution of claim 1 in which the amount of urobilinogen is from about 40 to about 400 mg/dl.

3. The control solution of claim 2 in which the amount of ethylene glycol is about 8.0% the protein is albumin, and the pH is from about 8.2 to about 8.4.

4. The control solution of claim 3 in which the inert gas is nitrogen.

5. The control solution of claim 1 in which the amount of ethylene glycol is about 8.0%.

6. The control solution of claim 1 in which the protein is albumin.

7. The control solution of claim 1 in which the pH is from about 8.2 to about 8.4.