Magnetic resonance imaging of high velocity flows
First Claim
1. A method of magnetic resonance imaging of moving substances, the method comprising;
- (a) applying a first broadband 180 degree inversion pulse;
(b) applying a 90 degree resonance excitation pulse and a first slice selection gradient;
(c) applying a first read gradient;
(d) applying a second broadband 180 degree inversion pulse;
(e) applying second, complementary read and slice selection gradients which substantially zero the effective first moment in time;
(f) applying phase encoding gradients;
(g) receiving a magnetic resonance signal; and
,(h) reconstructing an image from the resonance signal.
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Accused Products
Abstract
A main magnetic field coil and control cause a generally uniform main magnetic field through an image region. A resonance excitation control causes an R.F. coil to generate excitation pulses. An inversion pulse control causes the R.F. coil to generate a first 180 degree inversion pulse after the excitation pulse and a second 180 degree inversion pulse immediately preceding the excitation pulse. A slice gradient control and a read gradient control cause a gradient coil to generate complimentary slice selection gradients and complimentary read gradient profiles on either side of the first inversion pulse in such a manner that the effective first moment in time is substantially zero. By time shifting one or both of the slice selection and read gradients, resonating nuclei in the selected slice can be phase encoded. A transform algorithm transforms resonance signals received by the R.F. coil into image representations. A first memory receives real and imaginary components of the image representations when the read and slice selection gradients are not shifted and a second memory real and imaginary components of receives the image representations when one or both of the read and slice selection gradients are time shifted. From the arctangent of the real and imaginary components, first and second phase maps are calculated for storage in first and second phase memories. The intensity of each pixel of the phase maps varies with phase shift, hence velocity. By subtracting the two phase maps, correction is made for any stationary artifacts.
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Citations
22 Claims
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1. A method of magnetic resonance imaging of moving substances, the method comprising;
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(a) applying a first broadband 180 degree inversion pulse; (b) applying a 90 degree resonance excitation pulse and a first slice selection gradient; (c) applying a first read gradient; (d) applying a second broadband 180 degree inversion pulse; (e) applying second, complementary read and slice selection gradients which substantially zero the effective first moment in time; (f) applying phase encoding gradients; (g) receiving a magnetic resonance signal; and
,(h) reconstructing an image from the resonance signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method of magnetic resonance imaging comprising:
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(a) applying a resonance excitation pulse and a first slice selection gradient; (b) applying a first read gradient; (c) applying an inversion pulse to cause a spin-echo; (d) applying a second read gradient after the inversion pulse, the first and second read gradients being sized and timed relative to each other such that an effective first moment in time is substantially zero; (e) transforming received resonance signals into an image representation. - View Dependent Claims (10, 11, 12, 13, 14)
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15. A method of magnetic resonance imaging comprising:
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(a) applying a resonance excitation pulse; (b) applying a first slice selection gradient; (c) applying an inversion pulse; (d) applying a second slice selection gradient, the first and second slice selection gradients being sized and timed relative to each other such that an effective first moment in time is substantially zero; (e) applying a read gradient and reconstructing an image from received resonance signals. - View Dependent Claims (16, 17)
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18. A method of magnetic resonance examination of moving substances in an image region, the method comprising:
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acquiring a first magnetic resonance image having real and imaginary components with a first gradient profile applied to the image region; acquiring a second magnetic resonance image having real and imaginary components with the first gradient profile applied time shifted to the image region such that phases of the moving substances in the image region are affected selectively; creating a first phase map from the real and imaginary components of the first image; creating a second phase map from the real and imaginary components of the second image; and
,correcting for any stationary phase artifacts by taking a difference between the first and second phase maps.
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19. A magnetic resonance apparatus for examining moving substances, the apparatus comprising:
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a main magnetic field control means for generating a generally uniform magnetic field through an image region; at least one coil for transmitting and receiving radio frequency signals, the coil being disposed adjacent the image region; a resonance excitation control means for selectively causing the coil to transmit a resonance excitation pulse; an inversion pulse control means for selectively causing the coil to transmit a spin inversion pulse; a receiving means for receiving a radio frequency resonance signal received by from the coil; a gradient coil means for selectively causing magnetic field gradients across the main magnetic field; a slice selection gradient means for selectively causing the gradient coil means to generate gradients for selecting a slice through the image region to be imaged; a read gradient control means for selectively causing the gradient coil means to generate a read gradient across the slice; a phase encoder means for selectively causing the gradient coil means to phase encode resonating nuclei in the selected slice; a transform means for selectively transforming the resonance signal from the receiving means into an image representation which has real and imaginary values corresponding to each of a plurality of pixels; a first memory means for storing real and imaginary portions of a first image representation which is produced when the slice selection gradient control means and the read gradient control means apply slice selection and read gradients in such a manner that an effective first moment in time in the selected slice is substantially zero; a second memory means for storing real and imaginary portions of a second image representation which is produced when at least one of the slice selection gradient control means and the read gradient control means flow encodes resonating nuclei in the selected slice by shifting at least one of the respective slice selection and read gradients; a phase determining means for determining a phase map whose intensity values vary with phase shift, the phase determining means being operatively connected with the first and second memory means for determining at least first and second phase maps from the first and second images; a first and second phase map memory means for storing the first and second phase maps, the phase map memory means being operatively connected with the velocity determining means, and; a difference means for substractively combining the first and second phase maps to correct for any stationary artifacts the difference means being operatively connected with the first and second phase map memory means.
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20. A spin-echo magnetic resonance method for imaging flowing substances in a selected slice, the method comprising:
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(a) initially inverting a magnetization of selected dipoles of flowing and stationary substances inside and outside of the selected slice; (b) exciting magnetic resonance of the dipoles of the flowing and stationary substances in the selected slice only; (c) inverting the magnetization of the flowing and stationary substances inside and outside of the selected slices such that the dipoles of the substances outside of the selected slice during the magnetic resonance excitation are subject to two complimentary magnetization inversions and such that a spin echo is induced from the dipoles in which magnetic resonance was excited while in the selected slice; (d) applying a phase encode gradient; (e) during the spin echo, applying a read gradient and receiving magnetic resonance signals generated by the dipoles in which magnetic resonance was excited and which are inside and outside of the selected slice; (f) applying at least one additional gradient after exciting magnetic resonance and before the spin echo which additional gradient rephases the magnetization of resonating dipoles of components of the substance flowing perpendicular to the gradient relative to the magnetization of the resonating dipoles of the stationary substances and other components of the flowing substance, whereby the received magnetic resonance signals from a selected component of the flowing substance is distinguished by relative phase. - View Dependent Claims (21, 22)
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Specification