Nuclear magnetic resonance methods and apparatus

• US 4,683,432 A
• Filed: 09/18/1986
• Issued: 07/28/1987
• Est. Priority Date: 09/25/1985
• Status: Expired due to Fees

• Current Assignee: Picker International Ltd (Koninklijke Philips N.V.)
• Original Assignee: Picker International, Inc. (Koninklijke Philips N.V.)
• Inventors: Young, Ian R.
• Primary Examiner(s): Levy, Stewart J.
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US06/908,576
• Time in Patent Office: 313 Days
• Field of Search: 324/307, 324/309, 324/312, 324/310, 324/311
• US Class Current: 324/309
• CPC Class Codes: G01R 33/483 with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
• CPC Class Codes: G01R 33/485 based on chemical shift information [CSI] or spectroscopic imaging, e.g. to acquire the spatial distributions of metabolites

Abstract

A nuclear magnetic resonance method and apparatus for examining a predetermined particular location (55) in a body wherein processed data obtained from four procedures are combined to extract processed data relating to the particular location. Each procedure comprises exciting spins in a region (45) of the body including the location (55) and acquiring and processing data in respect of the excited spins. In a first procedure the excited spins are of the same phase throughout the region (45). In a second procedure the excited spins are of a first phase in a first portion (49) of the region (45) of which portion the predetermined location (55) forms part, and are of the opposite phase in the rest of the region (45). In a third procedure the excited spins are of a first phase in a second portion (53) of the region which intersects the first portion (45) at the predetermined location (55) and are of the opposite phase in the rest of the region (45). In a fourth procedure the excited spins are of a first phase in the first and second portions (49 and 53), excluding the predetermined location (55), and are of the opposite phase in the rest of the region (45). Adding the processed data signals from the first and fourth procedures and subtracting the processed data signals for the second and third procedures gives a resultant signal relating to the predetermined location (55) only.

Claims

1. A method of examining a predetermined location in a body using NMR techniques comprising:

carrying out four separate procedures each comprising exciting spins in a region of the body including said predetermined location and acquiring and processing data in respect of said spins, the procedures differing in that in a first procedure the excited spins are of the same phase throughout said region, in a second procedure the excited spins are of a first phase in a first portion of said region of which said predetermined location forms part and of the opposite phase in the rest of said region, in a third procedure the spins are of a first phase in a second portion of said region which intersects said first poriton at said predetermined location and are of the opposite phase in the rest of said region, and in fourth procedure the spins are of a first phase in the first and second poritons, excluding said predetermined location, and are of the opposite phase in the rest of said region; and

combining the processed data obtained in said four procedures to extract processed data relating to said predetermined location only.

2. A method according to claim 1 wherein the processed data are combined according to the formula

3. A method according to claim 1 wherein;

in said second procedure spins are excited by inverting spins in a first further region of said body which intersects said region at said first portion, and exciting spins in said region;

in said third procedure spins are excited by inverting spins in a second further region of said body which intersects said region at said second portion, and exciting spins in said region; and

in said fourth procedure said spins are excited by inverting spins in said first further region, inverting spins in said second further region, and exciting spins in said region.

4. A method according to claim 3 wherein said regions are all planar slices of the body.

5. A method according to claim 4 wherein said regions are mutually perpendicular.