Cardiac output measurement system and method

• US 4,685,470 A
• Filed: 11/18/1985
• Issued: 08/11/1987
• Est. Priority Date: 11/21/1984
• Status: Expired due to Term

• Current Assignee: Terumo Kabushiki Kaisha Trading As Terumo Corporation
• Original Assignee: Terumo Kabushiki Kaisha
• Inventors: Sekii, Shigehazu, Tanabe, Susumu
• Primary Examiner(s): Cohen, Lee S.
• Assistant Examiner(s): Shay, David
• Application Number:
  US06/799,001
• Time in Patent Office: 631 Days
• Field of Search: 128/692, 128/713, 364/716
• US Class Current: 600/505
• CPC Class Codes: A61B 5/028 by thermo-dilution
• CPC Class Codes: A61B 5/029 Measuring or recording blood output from the heart, e.g. minute volume A61B8/065 takes precedence

Abstract

An apparatus for measuring cardiac output includes a first system for obtaining cardiac output based on a thermal attenuation method and a second system for obtaining blood flow velocity based on a thermal-type flowrate measurement. A constituent value is obtained from the cardiac output and blood flow velocity, and the constituent value is held. The apparatus also includes a computing unit for computing cardiac output from the already obtained constituent value and a blood flow velocity obtained at the time of measurement. The constituent value can be updated by re-starting the first system.

Claims

1. A cardiac output measurement apparatus, comprising:

cardiac output obtaining means for obtaining cardiac output by a thermal attenuation method;

blood flow velocity means for obtaining blood flow velocity by a thermal-type flowrate measurement;

means for obtaining a constituent value functionally related to the cardiac output and blood flow velocity obtained by said cardiac output obtaining means and said blood flow velocity means;

storing means for holding the constituent value obtained;

means for starting said blood flow velocity means during continuous measurement instants;

means for updating said constituent value including means for initiating said cardiac output obtaining means to measure a new cardiac output; and

calculating means for calculating cardiac output from the constituent value held in said storing means and as updated by said updating means, and a newly obtained blood flow velocity each time said blood flow velocity means is started.

2. The apparatus according to claim 1, further comprising restarting means for restarting said cardiac output obtaining means, the constituent value being updated whenever said cardiac output obtaining means is restarted.

3. A cardiac output measurement apparatus comprising:

a catheter-type sensor having a liquid charging section and internally accommodating a first temperature-sensitive element for sensing blood temperature attenuated by a liquid and a heated second temperature-sensitive element;

first temperature detecting means for detecting a signal indicative of blood temperature sensed by said first temperature-sensitive element;

thermal attenuation-type cardiac output calculating means for calculating cardiac output based on a thermal attenuation method using an output signal from said first temperature detecting means;

second temperature detecting means for detecting a temperature of the heated second temperature-sensitive element;

blood flow velocity calculating means for calculating blood flow velocity based on an output signal from said second temperature detecting means and an output signal from said first temperature detecting means;

holding means for calculating, and for holding as a calibration value, a blood vessel cross-sectional area based on the cardiac output calculated by said thermal attenuation-type cardiac output calculating means and the blood flow velocity calculated by said blood flow velocity calculating means; and

cardiac output calculating means for calculating cardiac output based on the calibration value from said holding means and the blood flow velocity.

4. The apparatus according to claim 3, wherein said second temperature-sensitive element comprises a self-heating thermistor.

5. The apparatus according to claim 3, wherein said thermal attenuation-type cardiac output calculating means calculates cardiac output from an amount of injected liquid, temperature of the injected liquid, specific gravity of the injected liquid, specific heat of the injected liquid, blood temperature, specific gravity of the blood and a value obtained by integrating a thermal attenuation curve.

6. The apparatus according to claim 3, wherein said holding means comprises arithmetic means for comparing and calculating blood vessel cross-sectional area from the cardiac output value based on the thermal attenuation method and the blood flow velocity value, and sample-and-hold means for holding a value calculated by said arithmetic means.

7. The apparatus according to claim 4, wherein said blood flow velocity calculating means comprises means for calculating blood flow velocity from a constant-current value, blood temperature, and temperature and resistance value of said heated self-heating thermistor.

8. The apparatus according to claim 4, wherein said blood flow velocity calculating means comprises means for calculating blood flow velocity from a constant-current value, blood temperature, and the temperature of and potential difference developed by said heated self-heating thermistor.

9. A cardiac output measurement method, comprising:

a first step of obtaining cardiac output by a thermal attenuation method;

a second step of obtaining blood flow velocity by a thermal-type flowrate measurement;

a third step of obtaining a constituent value functionally related to the obtained cardiac output and blood flow velocity;

a fourth step of obtaining blood flow velocity at continuous measurement instants;

a fifth step of updating the constituent value by initiating said first step thereby obtaining a new cardiac output; and

a sixth step of obtaining cardiac output from the blood flow velocity obtained and the already obtained constituent value as updated in said fifth step.

10. The method according to claim 9, further comprising a step of re-starting said first step and updating the constituent value.