Method of making a reagent test device containing hydrophobic barriers

• US 4,687,529 A
• Filed: 05/15/1986
• Issued: 08/18/1987
• Est. Priority Date: 08/30/1985
• Status: Expired due to Fees

• Current Assignee: Miles Laboratories, Inc. (Bayer AG)
• Original Assignee: Miles Laboratories, Inc. (Bayer AG)
• Inventors: Wang, Joseph Y.
• Primary Examiner(s): Marcus, Michael S.
• Assistant Examiner(s): Hill, Jr., Robert J.
• Application Number:
  US06/863,295
• Time in Patent Office: 460 Days
• Field of Search: 422/56, 422/57, 422/58, 435/805, 427/2, 427/171, 428/49, 428/50, 156/163, 156/62.2, 156/299, 156/303
• US Class Current: 156/163
• CPC Class Codes: G01N 33/52 Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements immunological elements G01N33/54386; involving labelled immunochemicals G01N33/58; for haemoglobin or occult blood G01N33/72
• CPC Class Codes: Y10S 435/805 Test papers
• CPC Class Codes: Y10T 156/1092 All laminae planar and face to face

Abstract

Reagent test devices are prepared in which reagent carrier matrices are separated from each other by hydrophobic barrier pads of identical height to the reagent carrier matrices such that liquid present in a reagent matrix material is retained therein and prevented from running over into another reagent matrix area present on the same test device.

Claims

1. The process of forming a reagent test device comprising multiple reagent carrier matrices attached to a substrate with hydrophobic barrier pads of identical height to the reagent carrier matrices in physical contact with and separating adjoining spaced reagent carrier matrices, which comprises bending the substrate material from an original noncurved position so as to form a convex surface and then applying the reagent carrier matrices and hydrophobic barrier pads adjacent to each other on the convex surface of the substrate and thereafter permitting the substrate to return to its original noncurved position to obtain a test device having reagent carrier matrices and barrier pads of identical height in physical contact with each other to thereby protect the reagent carrier matrices from abrasion and to prevent liquid runover between adjoining spaced reagent carrier matrices.