Dialysis probe

• US 4,694,832 A
• Filed: 11/22/1985
• Issued: 09/22/1987
• Est. Priority Date: 12/01/1982
• Status: Expired due to Term

• Current Assignee: Cma/Microdialysis Holding AB
• Original Assignee: Carl U. Ungerstedt
• Inventors: Ungerstedt, Carl U.
• Primary Examiner(s): NOT, DEFINED
• Application Number:
  US06/800,374
• Time in Patent Office: 669 Days
• Field of Search: 128/632 E, 128/760, 128/769, 73/863.23
• US Class Current: 600/366
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 5/14528 invasively
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1678 intracorporal peritoneal dialysis A61M1/28
• CPC Class Codes: A61M 2025/0031 characterized by lumina for withdrawing or delivering, i.e. used for extracorporeal circuit treatment
• CPC Class Codes: A61M 2025/0037 characterized by lumina being arranged side-by-side
• CPC Class Codes: A61M 2025/0039 characterized by lumina being arranged coaxially
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2210/0693 Brain, cerebrum
• CPC Class Codes: A61M 25/0068 Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
• CPC Class Codes: A61M 25/0082 Catheter tip comprising a tool

Abstract

A dialysis probe, primarily intended for insertion in biological tissues, for example brain tissue, comprises a dialysis membrane and ducts for flow of the perfusion fluid over the membrane. The dialysis membrane in such a probe can be surrounded by a mounting which supports and partially reveals the membrane, and which is more rigid than the membrane.

Claims

1. A dialysis probe for insertion into biological tissues, comprising a hollow fibre dialysis membrane of uniform cross-sectional configuration throughout its length, an elongated mounting that surrounds and supports and includes means for partially exposing the outer surface of the membrane so that the outer exposed surface of the membrane is free to contact biological tissue in which the probe is inserted, the mounting having an exposed outer surface and being substantially more rigid than the membrane and having an internal diameter greater than the greatest external diameter of the membrane, and ducts for supplying and removing perfusion liquid to and from the interior of the membrane, one of said ducts extending to the distal end of the hollow fibre membrane and being open to the distal end of the membrane, said one duct being disposed inside the hollow fibre membrane and having an external diameter substantially less than the internal diameter of the hollow fibre membrane, the other duct communicating with the proximal end of the hollow fibre membrane, substantially all the inner surface of the membrane opposite said outer exposed surface of the membrane being exposed to the flow of liquid between said ducts.