Evoked potential autorefractometry system

• US 4,697,598 A
• Filed: 04/25/1985
• Issued: 10/06/1987
• Est. Priority Date: 04/25/1985
• Status: Expired due to Fees

• Current Assignee: Northrop Grumman Corporation
• Original Assignee: Westinghouse Electric Company LLC (Brookfield Asset Management Incorporated)
• Inventors: Sherwin, Gary W., Zomp, John M., Bernard, Thomas E., Mohan, Edwin R., Roth, Emile M
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US06/727,032
• Time in Patent Office: 894 Days
• Field of Search: 128/639-644, 128/731-732, 128/745, 128/802-803, 351/205, 351/216-217, 351/220
• US Class Current: 600/544
• CPC Class Codes: A61B 2562/222 Electrical cables or leads therefor, e.g. coaxial cables or ribbon cables
• CPC Class Codes: A61B 3/103 for determining refraction, e.g. refractometers, skiascopes
• CPC Class Codes: A61B 5/282 Holders for multiple electrodes for introduction into the body A61B5/287
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/377 using evoked responses
• CPC Class Codes: A61B 5/6814 Head

Abstract

An evoked potential autorefractometry system includes a computer driving an alternating checkerboard mirror stimulus to project a stimulus pattern directly to a patient through a continuously variable focus lens controlled by the computer and which maintains a constant image size on the patient'"'"'s retina. The evoked potentials produced by the patient are amplified, asychronously filtered both in an analog and digital fashion to allow peak to peak detection of the evoked potentials to determine amplitude. The digital filter includes a 255 point running sum. The peak to peak amplitudes are asychronously digitally filtered using a 16 point running sum to produce an amplitude measure of the evoked potentials. The lens is swept rapidly from one extreme of focus to the other extreme in relatively large steps to determine the area in which the peak amplitude occurs. The lens is then subsequently swept in smaller and smaller range sweeps using smaller and smaller steps around the peak amplitude until the peak in the amplitude is pinpointed within a desired diopter at which point the lens position is printed out on the printer as the patient'"'"'s prescription.

Claims

1. An evoked potential autorefractometry system for a patient, comprising:

stimulus production means for producing an alternating steady-state stimulus pattern;

a continuously variable focus lens projecting the stimulus pattern directly to the patient with a continuously changing focus and providing a fixed distance from the pattern to said lens;

evoked potential sensing means for sensing evoked potentials produced by the patient; and

control and determination means for determining the maximum amplitude of the evoked potentials, produced by the patient as the focus of the lens is continuously changed, by narrow band asychronous filtering the evoked potentials and detecting amplitude peaks of the evoked potentials.

2. A system as recited in claim 1, wherein the alternating steady-state stimulus pattern comprises an alternating checkerboard alternating at a frequency of approximately six cycles per second.

3. A system as recited in claim 2, wherein said alternating checkerboard has a spacial frequency of 8 cycles per inch at a distance of 32 inches.

4. A system as recited in claim 2, wherein said stimulus production means comprises:

a pair of light sources;

a chopper wheel alternately interrupting the light from said pair of light sources; and

a checkerboard mirror having a reflecting surface reflecting the interrupted light from one of the light sources of said pair toward the patient and transmitting the interrupted light from the other of the light sources of said pair toward said patient.

5. A system as recited in claim 4, wherein said stimulus production means further comprises:

a first matte filter transmitting the light from one of said pair of light sources;

a first beam splitter reflecting the light from said first filter toward a reflecting surface of said checkerboard mirror;

a second matte filter transmitting the light from the other of said pair of light sources; and

a second beam splitter reflecting the light from the second matte filter through said checkerboard mirror to the patient, the light reflected from and transmitted through the checkerboard mirror passes through said first beam splitter as the light is transmitted to the patient.

6. A system as recited in claim 4, wherein said stimulus production means further comprises:

a square wave generator;

a phase locked stepper motor control circuit operatively connected to said square wave generator; and

a stepper motor connected to said phase locked stepper motor control circuit and said chopper wheel.

7. A system as recited in claim 6, wherein said square wave generator produces a square wave at a frequency of 2.4 filohertz.

8. A system as recited in claim 6, wherein said phase locked stepper motor control circuit comprises:

a binary counter operatively connected to said square wave generator;

a read only memory operatively connected to said binary counter; and

power transistors operatively connected to said read only memory and said stepper motor.

9. A system as recited in claim 4, wherein said chopper wheel is a phase locked stepper motor controlled light chopper.

10. A system as recited in claim 1, wherein said continuously variable focus lens maintains a constant image size as perceived by the patient while continuously changing the focus.

11. A system as recited in claim 1, wherein said continuously variable focus lens comprises:

a fixed diopter lens receiving the stimulus pattern from said stimulus production means;

a focusable telescope, coupled to said fixed diopter lens, transmitting the stimulus pattern to the patient; and

focus means, coupled to said focusable telescope and operatively connected to said control and determination means, for continuously changing the focus of said focusable telescope.

12. A system as recited in claim 11, wherein said fixed diopter lens is a -1 diopter close-up lens and said focusable telescope is a 17×

60 telescope.

13. A system as recited in claim 1, wherein said evoked potential sensing means comprises an electroencephalographic cap.

14. A system as recited in claim 1, wherein said evoked potential sensing means comprises electrodes adapted to be positioned on a head of the patient.

15. A system as recited in claim 1, wherein said evoked potential sensing means comprises:

an adjustable headband; and

self-preparing electrodes mounted in said adjustable headband at positions for evoked potential measurement and adapted to penetrate a keratinous layer of skin and contact the epidermis without penetrating same.

16. A system as recited in claim 15, further comprising a shield for and partially surrounding said self-preparing electrodes and connected to ground.

17. A system as recited in claim 15, wherein said evoked potential sensing means further comprises a double shielded wiring system operatively connected to said selfpreparing electrodes and including inner and outer shields and a graphite layer adjacent the inner shield.

18. A system as recited in claim 15, wherein said evoked potential sensing means further comprises a low noise EEG probe wiring system operatively connected to said self-preparing electrodes.

19. A system as recited in claim 15, wherein each of said self-preparing electrodes is a subcaratinaceous EEB probe.

20. A system as recited in claim 15, wherein each of said self-preparing electrodes is a shielded self-preparing electrode suitable for EEB mapping.

21. A system as recited in claim 15, wherein said evoked potential sensing means further comprises electrolyte application means for applying an electrolyte to said self-preparing electrodes and the patient after said self-preparing electrodes are in position.

22. A system as recited in claim 21, wherein said electrolyte application means comprises:

a pump adapted to pump the electrolyte; and

tubing, connected to said pump and mounted adjacent to said self-preparing electrode, adapted to convey the electrolyte to said self-preparing electrodes.

23. A system as recited in claim 15, wherein said self-preparing electrodes each comprise:

a tulip probe; and

a spring urging said tulip probe through a dead layer of skin without causing bleeding.

24. A system as recited in claim 1, wherein said control and determination means comprises:

an amplifier, operatively connected to said evoked potential sensing means, receiving the evoked potentials and amplifying same;

a narrow band noise filter, operatively connected to said amplifier, filtering the evoked potentials to remove environmental noise;

an analog-to-digital converter, operatively connected to said narrow band noise filter, convering the evoked potentials into digital evoked potentials;

a computer, operatively connected to said analog-to-digital converter, determining the maximum amplitude of the digital evoked potentials as the focus of the lens is continuously changed, storing the lens position at the maximum amplitude and producing lens control signals; and

a lens control unit, operatively connected to said computer and said continuously variable focus lens, controlling the focus of said continuously variable focus lens in dependence upon the lens control signals.

25. A system as recited in claim 24, wherein said amplifier comprises a narrow band EEG amplifier.

26. A system as recited in claim 24, wherein said amplifier comprises:

a clipping circuit operatively connected to said evoked potential sensing means;

a pair of high impedance low gain amplifying circuits operatively connected to said clipping circuit;

a differential amplifier operatively connected to said pair of high impedance low gain amplifying circuits;

a first isolating capacitor operatively connected to said differential amplifier;

a first bandpass filter operatively connected to said first isolating capacitor;

a second isolating capacitor operatively connected to said first bandpass filter;

a second bandpass filter operatively connected to said second isolating capacitor;

a low pass filter operatively connected to said second bandpass filter;

a high pass filter operatively connected to said low pass filter and said noise filter; and

an amplifier shield surrounding said amplifier.

27. A system as recited in claim 24, wherein said noise filter comprises a narrow bandpass filter with a center frequency of six hertz.

28. A system as recited in claim 24,

wherein said stimulus production means produces a clock signal;

and

wherein said noise filter comprises a narrow band pass filter having a center frequency determined by the clock signal.

29. A system as recited in claim 24, wherein said computer includes:

means for filtering the evoked potentials using a first running sum;

means for detecting the peaks of the first running sum;

means for filtering the peaks using a second running sum; and

means for determining a maximum of the second running sum and storing the position of the continuously variable focus lens coincident with the maximum of the second running sum.

30. A system as recited in claim 24, wherein said lens control unit comprises:

a binary up/down counter operatively connected to said computer;

a read only memory operatively connected to said binary up/down counter;

power transistors operatively connected to said read only memory; and

a stepper motor operatively connected to said read only memory and mechanically coupled to said continuously variable focus lens.

31. A system as recited in claim 30, wherein said continuously variable focus lens includes a focus rod member for controlling the focus, and said system further comprises:

a first sprocket coupled to said focus rod member;

a second sprocket coupled to said stepper motor; and

a sprocket chain coupling said first and second sprockets.

32. An evoked potential autorefractometry system for prescribing a lens for a patient, said system comprising:

a square wave generator generating a square wave of 2.4 kilohertz;

a stimulus stepper motor and stimulus stepper motor control circuit, operatively connected to said square wave generator, turning said stimulus stepper motor at 3 hertz in dependence upon the square wave;

a stimulus generator including a checkerboard mirror and a light chopper wheel connected to said stimulus stepper motor, said light chopper wheel causing light to be alternately reflected from the checkerboard mirror toward the patient or transmitted through the checkerboard mirror toward the patient producing an alternating steady state stimulus pattern;

a continuously variable focus lens projecting the light from the stimulus generator to the patient while maintaining a constant image size and providing a fixed distance from the checkboard mirror to said lens;

an electoencephalographic cap having selfpreparing electrodes adapted to receive the evoked potentials produced by the patient in response to the light from said stimulus generator;

a shielded wiring system operatively connected to the self-preparing electrodes of said cap;

a shielded narrow bandwidth high gain amplifier operatively connected to said shielded wiring system;

a narrow bandwidth filter, operatively connected to said stepper motor control circuit and said narrow bandwidth high gain amplifier, filtering the evoked potentials;

a digital-to-analog converter, operatively connected to said narrow bandwidth filter, convering the filtered evoked potentials into digital values;

a computer, operatively connected to said digital-to-analog converter, asychronously digitally filtering the digital values using a first running sum technique, detecting the amplitude peaks of the first running sum, to digitally filtering the peaks using a second running sum technique, determining the maximum value of the digitally filtered peaks, storing a lens position of said continuously variable focus lens coincident with said maximum and producing lens position control signals; and

a lens position control circuit and lens stepper motor, operatively connected to said computer and coupled to said continuously variable focus lens, controlling the position of said continuously variable focus lens in dependence upon the lens position control signals.

33. A system as recited in claim 32, wherein said self-preparing electordes are adapted to penetrate a dead layer of skin without causing bleeding.

34. A system as recited in claim 32, wherein the first running sum is produced from 255 points and the second running sum is produced from 16 points.

35. A method for determining visual acuity, comprising:

a. stimulating a patient with an alternating steadystate stimulus pattern directly through a continuosly focusable constant image size lens;

b. continuously changing the focus of the lens while maintaining a fixed distance between the lens and the pattern;

c. detecting evoked potentials produced by the patient;

d. asychronously filtering the evoked potentials;

e. detecting the maximum amplitude of the evoked potentials as the focus of the lens is changed; and

f. storing the lens position of the maximum amplitude.

36. A method as recited in claim 35, wherein step d. includes producing a running sum of evoked potentials.

37. A method as recited in claim 36, wherein step e. includes:

ei. detecting a peak-to-peak amplitude of the running sum of evoked potentials; and

eii. producing a running sum of the peak-to-peak amplitude.

38. A continously variable focus lens system receiving a stimulus and transmitting the stimulus to a patient in an evoked potential autorefractometry system, said system comprising:

a fixed diopter lens receiving the stimulus while maintaining a fixed stimulus to lens distance;

a focusable telescope, coupled to said fixed diopter lens, transmitting the stimulus to the patient; and

focus means, coupled to said focusable telescope, for continuously changing the focus of said focusable telescope.

39. A lens system as recited in claim 38, wherein said fixed diopter lens is a +1 diopter close-up lens and said focusable telescope is a 17×

60 telescope.

40. A lens system as recited in claim 38, wherein said focus means comprises:

a stepper motor, mechanically coupled to said telepscope, for changing the focus of said telescope; and

stepper motor control means for controlling the rotation of said stepper motor.

41. A lens system as recited in claim 40, wherein said stepper motor control means comprises:

pulse means for generating up and down count pulses;

a binary up/down counter operatively connected to said pulse means;

a read only memory operatively connected to said binary up/down counter; and

power transistors operatively connected to said read only memory and said stepper motor.