Hydrophilic, elastomeric, pressure-sensitive adhesive

• US 4,699,146 A
• Filed: 09/12/1985
• Issued: 10/13/1987
• Est. Priority Date: 02/25/1982
• Status: Expired due to Term

• Current Assignee: Sherwood Services AG
• Original Assignee: Valleylab Inc. (Medtronic Plc)
• Inventors: Sieverding, David L.
• Primary Examiner(s): Bleutge, John C.
• Assistant Examiner(s): Koeckert, A. H.
• Application Number:
  US06/775,187
• Time in Patent Office: 761 Days
• Field of Search: 522/86, 522/152, 522/79, 128/639, 128/640, 128/641, 128/798, 128/802-803, 128/303.13, 252/518, 252/521
• US Class Current: 600/391
• CPC Class Codes: A61L 15/58 Adhesives
• CPC Class Codes: A61L 24/06 obtained by reactions only involving carbon-to-carbon unsaturated bonds A61L24/043, A61L24/046 take precedence
• CPC Class Codes: A61L 2400/14 Adhesives for ostomy devices
• CPC Class Codes: A61N 1/0456 Specially adapted for transcutaneous electrical nerve stimulation [TENS]
• CPC Class Codes: A61N 1/0468 Specially adapted for promoting wound healing
• CPC Class Codes: A61N 1/0496 characterised by using specific chemical compositions, e.g. hydrogel compositions, adhesives
• CPC Class Codes: C08L 2666/02 Organic macromolecular compounds, natural resins, waxes or and bituminous materials
• CPC Class Codes: C08L 2666/28 Non-macromolecular organic substances
• CPC Class Codes: C08L 2666/54 Inorganic substances
• CPC Class Codes: C09J 157/00 Adhesives based on unspecified polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: C09J 2301/302 the adhesive being pressure-sensitive, i.e. tacky at temperatures inferior to 30°C
• CPC Class Codes: C09J 7/10 without carriers
• CPC Class Codes: C09J 7/21 Paper; Textile fabrics
• CPC Class Codes: C09J 7/38 Pressure-sensitive adhesives [PSA]

Abstract

The present invention concerns a novel water-insoluble, hydrophilic, pressure-sensitive adhesive that has a number of unique characteristics including being elastomeric and ultraconformable. This adhesive includes an irradiation cross-linked synthetic organic polymer having a three-dimensional matrix, and an adhesive plasticizer. The plasticizer includes a substantially non-volatile elasticizer. The adhesive is useful either as a coating on a supporting web-like substrate or as a self-supporting layer. Also provided are various articles made using the adhesive such as a bandage or ostomy device, a method of making the adhesive, and methods of using the adhesive.

In one embodiment, the adhesive is electroconductive, and is useful for attaching an electrically conductive member of an electrode to a selected surface such as mammalian tissue. Also provided is an electrode having a layer of this adhesive, and a method of adhering this electrode to mammalian tissue.

Claims

1. An electroconductive, water-insoluble, hydrophilic, elastomeric pressure-sensitive adhesive comprising a gel of polyvinylpyrrolidone cross-linked by ionizing radiation, a polyalkylene glycol plasticizer, water and a salt selected from ammonium acetate, magnesium acetate or magnesium sulfate,

wherein said cross-linked gel is formed by irradiation of a solution or dispersion of said salt and said polyvinylpyrrolidone in said water and said plasticizer;

and

wherein said cross-linked gel retains said plasticizer within a cross-linked three-dimensional matrix of said polyvinyl pyrrolidone.

2. The adhesive of claim 1 wherein said plasticizer is present in an amount ranging from about 0.5 to 4 times the weight of said polymer.

3. The adhesive of claim 1 wherein said salt is magnesium acetate.

4. The adhesive of claim 1 wherein said plasticizer is polyethylene glycol.

5. The adhesive of claim 4 wherein said glycol has a molecular weight of about 300 or 600.

6. The adhesive of claim 5 wherein said glycol is present in an amount that is from about 0.75 to 1.5 times the weight of said pyrrolidone.

7. The adhesive of claim 1 wherein the said solution or dispersion comprises

(a) about 18 to 22 percent by weight of polyvinyl pyrrolidone,

(b) about 25 percent by weight of polyethylene glycol having a molecular weight of about 300,

(c) about 5 to 7 percent by weight of magnesium acetate, and

(d) water.

8. An electrode comprising an electrically conductive member and the electroconductive adhesive of claim 1, said adhesive being adapted to attach said member to mammalian skin.

9. The electrode of claim 8 which comprises an electrosurgical return electrode, a transcutaneous electrical nerve stimulation electrode or an EKG monitoring electrode.

10. The electrode of claim 8 which comprises an electrosurgical return electrode.

11. The electrode of claim 8 wherein said electroconductive adhesive is coated on a web-like substrate.

12. An electrosurgical return electrode comprising an electrically conductive member in electroconducting association with an electroconductive pressure-sensitive adhesive coated on a web-like substrate and adapted to attach said member to mammalian skin,

said adhesive being a radiation cross-linked gel comprising

about 20 percent by weight of K-90 polyvinyl pyrrolidone,

about 25 percent by weight of polyethylene glycol having a molecular weight of about 300,

about 5 percent by weight of magnesium acetate, and

about 50 percent by weight of water.

13. The electrode of claim 12 wherein said adhesive contains a compatible preservative.