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Transdermal drug applicator

  • US 4,708,716 A
  • Filed: 09/16/1985
  • Issued: 11/24/1987
  • Est. Priority Date: 08/18/1983
  • Status: Expired due to Term
First Claim
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1. A transdermal drug applicator for application to the body for migration of medicament through the skin to the blood stream of a patient comprising:

  • reservoir means containing at least one medicament, battery means for supplying a current to said applicator and being close to said reservoir means for charging/driving the medicament, means for covering comprising an electrically conductive material for partially enclosing at least said reservoir means leaving the side of said reservoir means opposite that of said battery means exposed for contacting said skin, means for electrically connecting the battery means to the cover means, said cover means having lip means for making contact with said skin when mounted on said skin leaving at least said reservoir means substantially fully enclosed, an electrically conductive adhesive material coating disposed on a side of said lip means in contact with the skin when in use, and a sensing electrode and circuit means in a feedback loop mounted on said skin when in use and connected with said electrical circuit for sensing a predetermined chemical in said body and providing a control signal for regulating drug dosage at a desired level, said applicator being generally conformable to the body contour of said patient, whereby when said applicator is adhered to and mounted on said skin a complete electrical circuit through said skin is formed and a medicament in said reservoir means migrates out of said reservoir means and through said skin into the blood stream of said patient, due to the mass transfer activity attributed to at least one phenomena selected from the group consisting of electrophoresis and electro-osmosis.

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