Sustained-release formulation containing an amino acid polymer with a lower alkyl (C.sub.1 -C.sub.4) polar solvent
First Claim
1. A sustained-release polymeric hydrogel dosage form useful for topical, systemic or transdermal administration of a medicinal agent comprising a cross-linked, polymerized hydrophilic polymer including an amino acid moiety in the polymer, in conjunction with a lower alkyl (C1 -C4) polar solvent and said medicinal agent in a therapeutically effective amount.
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Abstract
A sustained-release polymeric hydrogel dosage form useful for topical, systemic or transdermal administration of a medicinal agent comprising a cross-linked, polymerized hydrophilic polymer, an amino acid polymer, a cross-linking agent, and an optional hydrophobic monomer and/or a chain regulator in conjunction with a lower alkyl (C1 -C4), polar solvent and said medicinal agent in a therapeutically effective amount.
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Citations
24 Claims
- 1. A sustained-release polymeric hydrogel dosage form useful for topical, systemic or transdermal administration of a medicinal agent comprising a cross-linked, polymerized hydrophilic polymer including an amino acid moiety in the polymer, in conjunction with a lower alkyl (C1 -C4) polar solvent and said medicinal agent in a therapeutically effective amount.
Specification