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Measurement of ligand/anti-ligand interactions using bulk conductance

  • US 4,713,347 A
  • Filed: 01/14/1985
  • Issued: 12/15/1987
  • Est. Priority Date: 01/14/1985
  • Status: Expired due to Fees
First Claim
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1. A method for determining the presence of a ligand in a fluid sample comprising:

  • (a) localizing antiligand which interacts with said ligand in at least one predetermined region, said predetermined region being at least partially contained within a test volume;

    (b) exposing said predetermined region to said fluid sample; and

    (c) measuring the bulk conductance of said test volume to determine the occurrence of ligand-antiligand interaction in said predetermined region by detecting changes in the bulk conductance of said test volume due to ligand-antiligand interaction in said predetermined region.

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