Method of treating an injured part on the oral mucosa and the covering material for use thereof

• US 4,715,369 A
• Filed: 02/09/1987
• Issued: 12/29/1987
• Est. Priority Date: 12/29/1980
• Status: Expired due to Term

• Current Assignee: Teijin Limited
• Original Assignee: Teijin Limited
• Inventors: Suzuki, Yoshiki, Ikura, Hiroshi, Yamashita, Gentaro, Nagai, Tsuneji
• Primary Examiner(s): Lieberman, Paul
• Assistant Examiner(s): THERKORN, LINDA SKALING
• Application Number:
  US07/013,175
• Time in Patent Office: 323 Days
• Field of Search: 523/111, 128/156, 424/435, 424/434, 604/307
• US Class Current: 604/500
• CPC Class Codes: A61K 31/78 of acrylic acid or derivatives thereof
• CPC Class Codes: A61K 9/006 Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
• CPC Class Codes: A61L 15/24 Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof A61L15/225 takes precedence
• CPC Class Codes: A61L 15/28 Polysaccharides or their derivatives A61L15/225 takes precedence
• CPC Class Codes: C08L 1/28 Alkyl ethers
• CPC Class Codes: C08L 33/02 Homopolymers or copolymers of acids; Metal or ammonium salts thereof

Abstract

The present invention relates to a method for treating an injured part on the oral mucosa, which comprises covering the injured part with a covering material consisting essentially of a cellulose lower alkyl ether and a polyacrylic acid or its pharmaceutically acceptable salt, and to said covering material.

According to the present invention, without using a medicament, the injured part on an oral mucosa can be cured rather rapidly simply by covering the injured part.

Claims

1. A method for treating an injured part on the oral mucosa, which comprises covering the injured part with a covering material consisting of a medicament-free adhesive layer consisting essentially of cellulose lower alkyl ether and polyacrylic acid or its pharmaceutically acceptable salt and a medicament-free nonadhesive layer which has no adhesion to the wet surface of the oral mucosa.

2. A method for treating an injured part on the oral mucosa according to claim 1, wherein the nonadhesive layer comprises water-soluble or water-disintegrable components.

3. A method for treating an injured part on the oral mucosa according to claim 2, wherein the nonadhesive layer comprises one or more than one kinds of components selected from the group consisting of lactose, glucose, sucrose, starch, crystalline cellulose, dextrin, cyclodextrin, silicic acid anhydride, talc, calcium stearate, magnesium stearate, bees wax, polyethylene glycol, polyphosphate, anhydrous calcium phosphate and carboxymethyl cellulose calcium.