Implanted medication infusion device

• US 4,715,852 A
• Filed: 07/21/1986
• Issued: 12/29/1987
• Est. Priority Date: 07/21/1986
• Status: Expired due to Fees

• Current Assignee: Eaton Corp. (Wisconsin) (Eaton Corporation PLC.)
• Original Assignee: Eaton Corp. (Wisconsin) (Eaton Corporation PLC.)
• Inventors: Reinicke, Robert H., Yamato, Lance M.
• Primary Examiner(s): Rosenbaum, C. Fred
• Assistant Examiner(s): Kartchner, Gene B.
• Application Number:
  US06/888,585
• Time in Patent Office: 526 Days
• Field of Search: 604/131, 604/118, 604/121, 604/65-67, 604/326, 604/280, 604/283, 604/28, 128/79, 128/DIG. 12
• US Class Current: 604/131
• CPC Class Codes: A61M 1/884 Draining devices provided with means for filtering out the harmless water content before discarding the drainage container
• CPC Class Codes: A61M 2005/1652 Filter with duct, e.g. filtering element incorporated in a flow line, tube, duct
• CPC Class Codes: A61M 2205/0244 Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
• CPC Class Codes: A61M 5/141 with capillaries for restricting fluid flow
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/165 Filtering accessories, e.g. blood filters, filters for infusion liquids A61M1/14 , A61M1/34, A61M1/3627, A61M1/3679, A61M1/3687 take precedence; needle sets with incorporated air inlet filters A61M5/162
• CPC Class Codes: A61M 5/16804 Flow controllers
• CPC Class Codes: A61M 5/16877 Adjusting flow; Devices for setting a flow rate
• CPC Class Codes: F15C 5/00 Manufacture of fluid circuit elements; Manufacture of assemblages of such elements integrated circuits
• CPC Class Codes: Y10S 128/12 Pressure infusion

Abstract

An implantable positive pressure medication infusion device is provided which is programmable over a wide dynamic range and yet the maximum flow of medication into the body, in the event the inlet valve of the device leaks or fails in the valve open position, is limited to a safe value which is much lower than the maximum programmable infusion rate of the device. An auxiliary flow restrictor is also provided which bypasses the programmable pumping unit and assures a minimum flow of medication into the body in the event of failure of the programmable pumping unit or its electronic drive. An arrangement is also provided for detecting catheter clogging or failure of the programmable pumping unit in either a positive or negative pressure device.

Claims

1. In an implantable medication infusion device, the combination of, a medication reservoir having a movable wall portion, a pressure stabilizing chamber in communication with said movable wall portion and filled with a fluid having a pressure which is greater than the pressure of the body in which said device is implanted, a solenoid operated pulsatile pumping unit having an inlet communicating with said reservoir through an inlet valve;

and a flow restrictor positioned between said pumping unit and a catheter outlet, said flow restrictor permitting; and

continuous flow of medication to said catheter outlet at a safe value rate in the event said inlet valve remains open.

2. The combination of claim 1, wherein said pulsatile pumping unit provides a predetermined maximum flow rate through said flow restrictor, and said continuous flow of medication to said catheter when said inlet valve remains open is limited to approximately one-third of said predetermined maximum flow rate by said flow restrictor.

3. The combination of claim 2, wherein said predetermined maximum flow rate is approximately 0.36 milliliters per hour.

4. The combination of claim 3, wherein said continuous flow rate is approximately 0.11 milliliters per hour.

9. The combination of claim 1, wherein the continuous flow of medication through said flow restrictor is in the order of 0.11 milliliter per hour.

5. In an implantable medication infusion device, the combination of, a medication reservoir having a movable wall portion, a pressure stabilizing chamber in communication with said movable wall portion and filled with a fluid having a pressure which is greater than the pressure of the body in which said device is implanted, a solenoid operated pulsatile pumping unit having an inlet communicating with said reservoir through an inlet valve;

a first flow restrictor positioned between said pumping unit and a catheter outlet, and a second flow restrictor connected across said inlet valve, said second flow restrictor providing a predetermined continuous minimum flow of medication from said reservoir through said second and first flow restrictors to said catheter outlet during periods when said pumping unit is not operating.

6. The combination of claim 5, wherein said second flow restrictor comprises a large number of series connected orifices which collectively provide said predetermined continuous minimum flow.

7. The combination of claim 5, wherein said first flow restrictor also limits the continuous flow of medication from said reservoir to said catheter to a predetermined value in the event said inlet valve does not function properly, said predetermined value being greater than said continuous minimum flow of said second flow restrictor but substantially less than the maximum flow rate when said pumping unit is operating.

8. The combination of claim 5, wherein said predetermined continuous flow provided by said second flow restrictor is in the order of 2.5 microliters per hour.

10. The combination of claim 7, wherein said predetermined value is in the order of 0.11 milliliters per hour.

11. The combination of claim 7, wherein said maximum flow rate when said pumping unit is operating is in the order of 0.36 milliliters per hour.

12. In an implantable medication infusion device, the combination of a medication reservoir, means for supplying medication from said reservoir to a catheter outlet port, said catheter outlet port including an inwardly extending shoulder, and a quick detachable outlet port connector having a connector body adapted to fit into said catheter outlet port in fluid sealing relation thereto and having a pair of spring arms provided with outwardly extending lug portions on the free ends thereof which are adapted to engage said shoulder and hold said connector securely within said outlet port, said spring arms being inwardly deflectable to disengage said lug portions from said shoulder, thereby to permit said connector to be quickly removed from said outlet port.

13. The combination of claim 12, wherein said connector body includes a pair of rigid arms contiguous to said pair of spring arms, each of said rigid arms having an aperture therein through which said spring arms may be deflected.

14. The combination of claim 12, wherein said connector body includes at least one groove within which is positioned an O ring to provide said fluid sealing relation between said connector body and said catheter outlet port.

15. The combination of claim 12, which includes means for interlocking said connector within said catheter outlet port in a plurality of orientations relative to said outlet port.

16. The combination of claim 12, which includes means carried by said outlet port connector for securing a catheter thereto.

17. In an implantable medication infusion device, the combination of, a medication reservoir having a movable wall portion, a pressure stabilizing chamber in communication with said movable wall portion and filled with a fluid having a pressure which is greater than the pressure of the body in which said device is implanted, a solenoid operated pulsatile pumping unit having an inlet communicating with said reservoir through an inlet valve;

a first flow restrictor positioned between said pumping unit and a catheter outlet, and a second flow restrictor connected between said reservoir and said catheter outlet, said second flow restrictor providing a predetermined continuous minimum flow of medication from said reservoir to said catheter outlet during periods when said pumping unit is not operating.

18. The combination of claim 17, wherein said second flow restrictor comprises a large number of series connected orifices which collectively provide said predetermined continuous minimum flow.

19. The combination of claim 17, wherein said first flow restrictor also limits the continuous flow of medication from said reservoir to said catheter to a predetermined value in the event said inlet valve does not function properly, said predetermined value being greater than said continuous minimum flow of said second flow restrictor but substantially less than the maximum flow rate when said pumping unit is operating.

20. The combination of claim 17, wherein said predetermined continuous flow provided by said second flow restrictor is in the order of 2.5 microliters per hour.