Method for determining systolic arterial blood pressure in a subject
First Claim
1. A method for determining systolic arterial blood pressure in a subject comprising the steps of:
- controllably deflating an occlusive cuff secured around a limb of the subject,detecting a pre-determined number of pressure waveform peaks and simultaneously occurring corresponding occlusive cuff pressures occurring during occlusive cuff deflation,determining a first measure of the variability of these detected peaks,defining co-ordinates of a first point in terms of an average of the detected peaks and an average of the corresponding occlusive cuff pressures,successively maintaining the pressure of said occlusive cuff at a substantially constant value for a corresponding pre-selected time interval and detecting additional pressure waveform peaks and determining a second measure of the variability associated therewith during said corresponding time interval,defining co-ordinates of a second point in terms of an average of said additional peaks and said constant pressure value,modifying the values of the co-ordinates of said first and/or second points, in response to said first and/or second variability measures,ascertaining an intermediate value of systolic pressure in terms of the co-ordinates of a point of intersection between a line defined by said first and second points and a line representing a pre-determined constant pressure value, andmodifying said intermediate systolic pressure value in response to said first and/or second variability measures so as to obtain a final systolic pressure value.
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Abstract
Apparatus and related methods for continuous long-term non-invasive measurement of the pressure of a pulsatile fluid flowing through a flexible tube, particularly human arterial blood flow, is disclosed. Specifically, the apparatus provides a continuous calibrated pressure measurement by first undertaking a "calibration" phase comprised of determining the pressure at various pre-defined conditions of flow and, in response thereto, ascertaining the values of a plurality of coefficients each of which is associated with a corresponding term in a pre-defined function that characterizes fluid pressure in relation to pulsatile displacement of the wall of the tube; and second, undertaking a "continuous monitoring" phase comprised of determining each subsequently occurring pressure value as the pre-defined function of each corresponding pulsatile wall displacement value, and re-initiating the calibration phase at the expiration of pre-defined time intervals which adaptively change based upon current and prior results. Methods, which are particularly useful in conjunction with the disclosed apparatus, for ascertaining systolic and diastolic arterial blood pressure values are also disclosed.
72 Citations
7 Claims
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1. A method for determining systolic arterial blood pressure in a subject comprising the steps of:
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controllably deflating an occlusive cuff secured around a limb of the subject, detecting a pre-determined number of pressure waveform peaks and simultaneously occurring corresponding occlusive cuff pressures occurring during occlusive cuff deflation, determining a first measure of the variability of these detected peaks, defining co-ordinates of a first point in terms of an average of the detected peaks and an average of the corresponding occlusive cuff pressures, successively maintaining the pressure of said occlusive cuff at a substantially constant value for a corresponding pre-selected time interval and detecting additional pressure waveform peaks and determining a second measure of the variability associated therewith during said corresponding time interval, defining co-ordinates of a second point in terms of an average of said additional peaks and said constant pressure value, modifying the values of the co-ordinates of said first and/or second points, in response to said first and/or second variability measures, ascertaining an intermediate value of systolic pressure in terms of the co-ordinates of a point of intersection between a line defined by said first and second points and a line representing a pre-determined constant pressure value, and modifying said intermediate systolic pressure value in response to said first and/or second variability measures so as to obtain a final systolic pressure value. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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Specification
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- Resources
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Current AssigneeCortronic Corporation
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Original AssigneeCortronic Corporation
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InventorsRussell, Ted W.
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Primary Examiner(s)Howell, Kyle L.
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Assistant Examiner(s)NOT, DEFINED
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Application NumberUS07/006,627Time in Patent Office355 DaysField of Search128/672, 128/677-686US Class Current600/492CPC Class CodesA61B 2560/0223 of calibration, e.g. protoc...A61B 5/021 Measuring pressure in heart...A61B 5/02156 Calibration meansA61B 5/022 by applying pressure to clo...A61B 5/0235 Valves specially adapted th...
